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- Cold Ischemia Time (CIT)
- The time interval that begins when an organ is cooled with a cold perfusion solution after organ procurement surgery and ends when the organ is implanted.
- Division of Transplantation (DoT)
- The DoT is a component of the Office of Special Programs in the Health Resources and Services Administration (HRSA). The DoT regulates and provides federal oversight and funding support for the nation's organ procurement, allocation, and transplantation system; coordinates national organ and tissue donation activities; funds research to improve donation rates; and administers the National Bone Marrow Registry program.
- Donation Service Area
- The geographical service area designated by the Federal Government and assigned to an Organ Procurement Organization (OPO) for recovering organs from all hospitals in that region. DSA designation and OPO assignments are made every four years beginning in 2002 (every two years from 1998-2001) by the Centers for Medicare and Medicaid Services (CMS). Detailed lists of counties within each DSA can be found in Table 9 of the OPO reports at www.ustransplant.org.
- Final Rule
- The Organ Procurement and Transplantation Network (OPTN) Final Rule (42 CFR Part 121) was issued and published in the Federal Register on April 2, 1998. This rule governs the operation of the OPTN and was amended (resulting from the Institute of Medicine's report, Organ Procurement and Transplantation, 1999). It was issued and published in the Federal Register on October 20, 1999. The Final Rule went into effect on March 16, 2000.
- National Organ Transplant Act (NOTA)
- The National Organ Transplant Act (1984 Public Law 98-507), approved October 19, 1984 and amended in 1988 and 1990, provided for the establishment of the Task Force on Organ Transplantation; authorized the Secretary of HHS to make grants for the planning, establishment, and initial operation of qualified OPOs; and established the formation of the Organ Procurement and Transplantation Network (OPTN) and Scientific Registry of Transplant Recipients (SRTR).
- OPO
- See Organ Procurement Organization.
- Organ Preservation
- Between procurement from a donor and transplantation into a recipient, organs require special methods of preservation. The length of time that organs and tissues can be kept outside the body varies, depending on the organ, the preservation fluid, and the temperature.
- Organ Procurement
- Organ Procurement and Transplantation Network (OPTN)
- Under a contract from HRSA and with oversight from the DoT, the OPTN operates the national network for organ procurement and allocation and works to promote organ donation. Through its policies, the OPTN works to ensure that all patients have a fair chance at receiving the organ they need, regardless of age, sex, race, lifestyle, religion, or financial or social status. The current OPTN contractor is the United Network for Organ Sharing (UNOS), based in Richmond, Virginia.
- Organ Procurement Organization (OPO)
- A certified, not-for-profit organization designated by CMS to be responsible for the procurement of organs for transplantation and the promotion of organ donation within a given Donation Service Area (DSA). There are 59 OPOs nationwide that facilitate the organ donation process by assessing in-hospital deaths for donor eligibility; consulting with families of potential donors; and retrieving, preserving, and transporting organs for transplantation.
- Procurement
- The process of donor screening and the evaluation, removal, preservation, and distribution of organs, tissues, or cells for transplantation.
Available Terms:
ABO Blood Type
Actual Donor
Additional Donor
Advisory Committee on Organ Transplantation (ACOT)
Allocation Policies
Allograft
Annual Death Rate
Antibody
Antigen
Cadaveric Donor
Cadaveric Transplant
Cardiomyopathy
Censoring
Centers for Medicare and Medicaid Services (CMS)
Chimerism
Cockcroft-Gault Formula
Cohort
Cold Ischemia Time (CIT)
Compliance
Confidence Interval
Congenital Heart Disease
Coronary Artery Disease
Creatinine
Crossmatch
Death Rate
Deceased Donor
Division of Transplantation (DoT)
Donation Rate
Donation Service Area
Donor
Donor Cardiac Death (DCD)
DSA
DSA
Eligible Donor
Emphysema
End-Stage Organ Failure
End-Stage Renal Disease (ESRD)
Ethnicity
Expanded Criteria Donor (ECD)
Expanded Criteria Donor (ECD) Kidneys
FEV1
Final Rule
Glomerular Filtration Rate (GFR)
Graft
Graft Survival
Haplotype
HCFA
Health Resources and Services Administration (HRSA)
Heterotopic Transplant
Histocompatibility Antigens
Human Leukocyte Antigen System (HLA System)
Immunogenicity
Immunosuppression
Induction Therapy
Informed Consent
Inotropes
Justice
Living Donor
Median Time to Transplant
Median Waiting Time
Medical Urgency Status Codes
Medical Urgency Status Codes for Heart Allocation (1999-2002)
Medical Urgency Status Codes for Heart Allocation (Pre-1999)
Medical Urgency Status Codes for Liver Allocation (1997)
Medical Urgency Status Codes for Liver Allocation (1997-2000)
Medical Urgency Status Codes for Liver Allocation (Pre-1997)
Mismatch
Model for End-Stage Liver Disease (MELD)
National Organ Transplant Act (NOTA)
Nonheartbeating Donor
OPO
Organ Preservation
Organ Procurement
Organ Procurement and Transplantation Network (OPTN)
Organ Procurement Organization (OPO)
Panel Reactive Antibody (PRA)
Patient Survival
Pediatric End Stage Liver Disease (PELD) Scoring System
Percentile
Procurement
Race
Recipient
Rejection
Scientific Registry of Transplant Recipients (SRTR)
Sensitization
Standard Error
Thoracic Organs
Time to Transplant (TT)
Tissue Type
Transplant Center
Transplant Program
Tumor
United Network for Organ Sharing (UNOS)
University Renal Research and Education Association (URREA)
Utility
Vascular
Ventricular Assist Device (VAD)
Waiting List
Waiting List (Active)
Waiting List (Inactive)
Waiting List (Removal)
Waiting Time