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Immunosuppression
The suppression of the immune response, usually with medications, to prevent the rejection of a transplanted organ or tissue. Medications commonly used to suppress the immune system after transplantation include prednisone, methylprednisolone, azathioprine, mycophenalate mofetil, cyclosporine, tacrolimus, and rapamycin, among others.
Induction Therapy
The administration of a brief course of high-dose immunosuppression in the early posttransplant period. Induction therapy precedes and overlaps with less intense long-term maintenance immunosuppression.
Tumor
An abnormal growth of tissue resulting from an uncontrolled multiplying of cells that serves no physiological function. Tumors can be either malignant (cancerous) or benign (non-cancerous). Malignant tumors include newly developed or de novo solid tumors as well as recurrent tumors that had previously been successfully treated. Posttransplant lymphoproliferative disorders (PTLD) are abnormal accumulations of immune cells brought about by the immunosuppression therapies used to reduce organ rejection.

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The Scientific Registry of Transplant Recipients is administered by URREA in conjunction with the University of Michigan.

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