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Transplant Statistics: Annual Report


Annual Report | Data Highlights | Data By Category | Data By Organ | Technical Notes | Glossary | Appendices

Technical Notes and Analytic Methods
Transplants and Transplant Recipient Characteristics

Tables 1.8, 1.9, and 1.10 present counts of all U.S. single and multi-organ transplants by organ and donor type and by selected recipient demographic and medical characteristics. Organ-specific recipient characteristics are presented in Table 4 of each of the organ-specific sections.

Transplant recipient characteristic data are based primarily on the OPTN TCR and TRR forms. Transplant counts are based on the OPTN donor feedback process, which begins the process of tracking a transplant based on donor organ allocation, or on living donor transplant reports from transplant centers. When a patient is wait-listed or receives a living donor transplant, a TCR form is completed by a transplant center and submitted to the OPTN for processing. The TRR form is completed by a transplant center after a transplant and is submitted to the OPTN for processing.

While kidney-pancreas and heart-lung transplants are shown as one transplant, other multi-organ transplants of two different organ types appear in each organ-specific table. For example, a kidney-liver transplant would be included in both the kidney data and the liver data.

Table 1.8  presents a breakdown of transplants for all organs by cadaveric donor versus living donor. Because living donor pancreas, intestine, heart (from heart-lung recipients who donate their viable heart), and lung transplants are rare, recipients of such transplants are reported only in Table 1.8. Each organ section only includes cadaveric donor transplants unless it is explicitly stated otherwise, as is the case with kidneys and livers. Counts reflect the number of transplants, not the number of organs; therefore, each donor is not counted if there are multiple donors, such as may be the case with living donor lung lobar transplants.

The organ-specific tables show, for particular characteristics, the number and percentage of transplants by category, for each year, for that type of transplant. Some characteristics may have unknown values. This occurs when transplant centers report values as unknown, or when forms are still outstanding. The percentages in the tables are based on the total reported categories, including the unknown cases. The data are subject to change due to future data submission or correction.

Particular recipient characteristics are discussed below.

Patient Description, Type of Procedure. These data are collected via the TRR form. Unknown cases are accounted for primarily by data being missing or reported as unknown on TRR forms or by TRR forms being delinquent. In the Type of Procedure for lung transplants, en bloc and bilateral sequential transplants are included in the double lung category; lung lobe transplants are included in the single lung category.

Age, Race, Ethnicity, Gender, Blood Type, and Residency. These data are collected via the TCR form. Unknown cases are accounted for primarily by incomplete TCR forms or by forms not yet received. The Asian group includes Pacific Islanders, which is a separate category on the current TCR form. In the residency table, U.S. residents include both U.S. citizens and resident aliens.

Previous Transplant. This is an indicator of whether a patient had a previous transplant of any solid organ. To determine if a recipient has had a previous transplant, the database first is searched for any records of previous transplant with the same recipient identification number. Data collected on the TRR and TCR forms are then considered.

Previous Transplant of the Same Organ. This is an indicator of a previous transplant of the same organ type. To determine if a recipient has had a previous transplant, the database first is searched for any records of previous transplant of the same organ type with the same recipient identification number. Data collected on the TRR and TCR forms are then considered. For kidney-pancreas transplants, only a previous simultaneous kidney-pancreas transplant is considered to be a previous transplant. For kidney alone and pancreas alone transplants, a previous transplant could be either a previous transplant of that same organ type or a previous simultaneous kidney-pancreas transplant. Similarly, for heart alone and lung alone transplants, a previous transplant could be either a previous transplant of that same organ type or a previous simultaneous heart-lung transplant.

Hospitalized at Transplant, Life Support at Transplant. These variables refer to the patient's condition immediately prior to the transplant procedure. In the tables, "Hospitalized" refers to patients hospitalized but not in the intensive care unit.

PRA (Panel Reactive Antibody). PRA, at time of transplant, is shown only for kidney and kidney-pancreas recipients. This item is taken from the Recipient Histocompatibility (RH) Form. Unknown cases are accounted for primarily by incomplete RH forms or by forms not yet received.

Level of HLA Mismatch. This variable is shown only for kidney and kidney-pancreas transplants and represents the number of HLA antigens found in the donor that are not shared by the recipient. This value is based on the six HLA antigens (two each for the A, B, and DR loci) reported for both the donor, on the donor histocompatibility (DH) form, and the recipient, on the recipient histocompatibility (RH) form. Unknown cases are accounted for primarily by incomplete DH or RH forms or by forms not yet received. Mismatched antigens are identified according to the OPTN criteria regarding "split" and "parent" antigens.

Waiting List Status at Transplant. For liver and heart transplants only, the waiting list status at transplant was determined by linking each transplant back to the waiting list history file, a file which was intended to track centers' changes to the waiting list over time. The waiting list status represents the patient's degree of medical urgency; using pre-1997 and current definitions these are status levels 1, 2, 2A, 2B, 3, and 4 for liver and 1, 1A, 1B, and 2 for heart, with 1s (or 1A) being the most urgent. Status codes are defined in detail in the Glossary.
 



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