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Research Resources: Analytic Conventions - Model Description (Lung)

Model Descriptions on This Page

Graft Survival Model Description

Adult (Age 18+)

Patient Survival Model Description

Adult (Age 18+)

Graft Survival Model Description
1 Month after Transplant
Organ: Lung
Adult (Age 12+)


Patient Characteristic Covariates	beta	standard error	p-value


Diagnosis: Emphysema/COPD and Alpha-1-Antitrypsin Deficiency (95.4% alive at 1 Month when all covariates=0.)
CMV mismatch: donor CMV positive, recipient CMV negative	-0.1256	0.3195	0.6943
Diagnosis: obliterative bronchiolitis or bronchiectasis	0.8194	0.5297	0.1219
Distance between recipient and donor centers: miles (ref=mean distance*)	-0.0009	0.0007	0.2108
Hemodynamics PCW pressure: 20+ (ref=mean*)	-12.2318	516.1100	0.9811
Hemodynamics PCW pressure: linear (ref=mean*)	0.0492	0.0299	0.0998
Hemodynamics PCW pressure: missing (ref=mean*)	-0.0076	0.2828	0.9785
Previous transplant of this organ type	0.6792	0.6660	0.3078
Recipient age: years (ref=mean age*)	0.0080	0.0153	0.6001
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.7111	0.7298	0.3298
Recipient medical condition: in ICU (ref=not hospitalized)	0.9596	0.6396	0.1336
Recipient six minute walk distance < 150 ft at listing: unknown or missing	-0.1150	0.4750	0.8088
Recipient six minute walk distance < 150 ft at listing: yes	0.1791	0.4431	0.6861
Hemodynamics PA (mean) by diagnosis interaction: mean PA 30 or less and sarcoidosis	0.8687	1.0266	0.3975

Diagnosis: Primary Pulmonary Hypertension and Eisenmengers (88.7% alive at 1 Month when all covariates=0.)
Diagnosis: pulmonary vascular disease	0.3928	1.1006	0.7212
Donor race: Black	0.3712	1.0709	0.7289
Recipient creatinine: linear (ref=mean creatinine*)	-0.9730	1.3568	0.4733
Recipient on Ventilator	1.3011	1.0697	0.2239

Diagnosis: Cystic Fibrosis (97.2% alive at 1 Month when all covariates=0.)
Donor race: Black	0.5816	0.7047	0.4092
Ischemia time: linear (ref=average time*)	-0.3759	0.2191	0.0862
Ischemia time: quadratic (ref=average time*)	0.0910	0.0401	0.0232
Ischemia time: missing (ref=average time*)	0.4910	0.7344	0.5038
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.6540	0.8338	0.4329
Recipient medical condition: in ICU (ref=not hospitalized)	1.6352	1.3886	0.2390
Recipient on Ventilator	0.6299	1.4322	0.6601
Recipient previous transfusions at listing: unknown or missing	-0.2445	0.8000	0.7599
Recipient previous transfusions at listing: yes	0.1299	1.0672	0.9031

Diagnosis: Idiopathic Pulmonary Fibrosis and not classified (94.4% alive at 1 Month when all covariates=0.)
ABO compatibility: compatible	-0.0425	0.5375	0.9369
Diagnosis: not classified	1.2316	0.4515	0.0064
Diagnosis: pulmonary fibrosis other	0.0759	0.5356	0.8873
Donor CMV: positive	-0.0975	0.2942	0.7402
Donor age: 46+	0.5054	0.3073	0.1000
Donor creatinine: linear (ref=mean donor creatinine*)	-0.0358	0.1391	0.7969
Donor creatinine: missing (ref=mean donor creatinine*)	-12.2776	1494.8165	0.9934
Donor race: Black	0.4829	0.3456	0.1624
Donor smoked in last six months: yes	-0.3556	0.3706	0.3372
Donor used cocaine, IV drugs or other drugs in last six months: yes to any	-0.4593	0.4549	0.3127
Hemodynamics PA (systolic): linear (ref=mean*)	0.0255	0.0102	0.0127
Hemodynamics PA (systolic): missing (ref=mean*)	0.8099	0.3143	0.0100
Ischemia time: linear (ref=average time*)	0.0402	0.1044	0.7005
Ischemia time: missing (ref=average time*)	0.3886	0.3263	0.2336
Previous transplant of this organ type	0.4581	0.6102	0.4528
Recipient angina/CAD at listing: angina, stable or stability unknown	0.7408	0.4964	0.1356
Recipient angina/CAD at listing: angina, unstable	-12.4295	698.8316	0.9858
Recipient angina/CAD at listing: missing	-0.2601	1.0371	0.8020
Hemodynamics PA (mean) by diagnosis interaction: mean PA missing and sarcoidosis	0.5047	0.5911	0.3932



* Ischemia time is centered on 4.53 hours; recipient age is centered on 49.64 ; recipient serum creatinine is centered on 0.92 mg/dl; donor serum creatinine is centered on 1.13 mg/dl; hemodynamics PA (systolic) is centered on 41.16 mm/Hg; hemodynamics PCW pressure is centered on 11.73 mm/Hg; distance between recipient and donor centers is centered on 180.51 miles.

Graft Survival Model Description
1 Year after Transplant
Organ: Lung
Adult (Age 12+)


Patient Characteristic Covariates	beta	standard error	p-value


Diagnosis: Emphysema/COPD and Alpha-1-Antitrypsin Deficiency (84.8% alive at 1 Year when all covariates=0.)
CMV mismatch: donor CMV positive, recipient CMV negative	0.1406	0.1573	0.3717
Diagnosis: lymphangioleiomyomatosis	-0.2012	0.6008	0.7377
Diagnosis: obliterative bronchiolitis or bronchiectasis	0.1623	0.3609	0.6530
Distance between recipient and donor centers: miles (ref=mean distance*)	-0.0003	0.0003	0.3416
Donor Hispanic/Latino	0.3221	0.2325	0.1660
Donor race: Asian	0.0480	0.5872	0.9348
Donor race: Black	0.1523	0.1982	0.4423
Donor race: Multi-racial, other, unknown or missing	0.2162	0.7247	0.7655
Hemodynamics PCW pressure: 20+ (ref=mean*)	-12.1301	314.4407	0.9692
Hemodynamics PCW pressure: linear (ref=mean*)	0.0023	0.0171	0.8912
Hemodynamics PCW pressure: missing (ref=mean*)	-0.0186	0.1519	0.9027
Ischemia time: linear (ref=average time*)	0.0844	0.0587	0.1505
Ischemia time: quadratic (ref=average time*)	0.0016	0.0163	0.9199
Ischemia time: missing (ref=average time*)	0.4347	0.1738	0.0124
Previous transplant of this organ type	0.9630	0.4425	0.0295
Recipient age: years (ref=mean age*)	0.0170	0.0088	0.0521
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	-0.1280	0.5245	0.8073
Recipient medical condition: in ICU (ref=not hospitalized)	-0.2750	0.6023	0.6480
Recipient on Ventilator	1.6145	0.5341	0.0025
Recipient six minute walk distance < 150 ft at listing: unknown or missing	0.4459	0.2090	0.0329
Recipient six minute walk distance < 150 ft at listing: yes	-0.2012	0.2815	0.4748
Hemodynamics PA (mean) by diagnosis interaction: mean PA 30 or less and sarcoidosis	0.5327	0.5934	0.3694

Diagnosis: Primary Pulmonary Hypertension and Eisenmengers (76.5% alive at 1 Year when all covariates=0.)
Diagnosis: pulmonary vascular disease	0.7637	0.8324	0.3589
Donor BMI: 30+	-0.1339	0.7712	0.8622
Donor age: 0-17	1.4734	0.6261	0.0186
Donor age: 18-34	-0.3943	0.6457	0.5415
Donor age: 50+	0.4833	0.7195	0.5017
Donor race: Black	-0.6396	0.7739	0.4085
Recipient creatinine: linear (ref=mean creatinine*)	0.3736	0.8733	0.6688
Recipient on Ventilator	1.3678	0.8183	0.0946

Diagnosis: Cystic Fibrosis (75.8% alive at 1 Year when all covariates=0.)
	1.1706	1.0659	0.2721
Donor age: 0-17	-0.1112	0.3888	0.7748
Donor age: 18-34	-0.3159	0.3641	0.3856
Donor age: 50+	0.3115	0.5497	0.5709
Donor race: Black	0.2944	0.3972	0.4586
Ischemia time: linear (ref=average time*)	-0.0733	0.1344	0.5856
Ischemia time: quadratic (ref=average time*)	0.0350	0.0239	0.1426
Ischemia time: missing (ref=average time*)	0.0317	0.4250	0.9405
Recipient age: 12-17	-0.0279	0.4911	0.9547
Recipient age: 18-34 (ref=35-49)	-0.3844	0.3234	0.2345
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.1520	0.4670	0.7449
Recipient medical condition: in ICU (ref=not hospitalized)	1.0762	0.8491	0.2050
Recipient on Ventilator	0.4943	0.8818	0.5751
Recipient previous transfusions at listing: unknown or missing	-0.2675	0.3740	0.4745
Recipient previous transfusions at listing: yes	-1.5174	1.0272	0.1396

Diagnosis: Idiopathic Pulmonary Fibrosis and not classified (83.9% alive at 1 Year when all covariates=0.)
ABO compatibility: compatible	-0.3276	0.3551	0.3561
Diagnosis: not classified	0.6071	0.3335	0.0687
Diagnosis: obliterative bronchiolitis (not retransplanted)	-0.1308	0.5984	0.8270
Diagnosis: pulmonary fibrosis other	-0.0574	0.3227	0.8588
Donor CMV: positive	0.3726	0.1826	0.0413
Donor age: 46+	0.4277	0.1961	0.0292
Donor creatinine: linear (ref=mean donor creatinine*)	-0.0769	0.1187	0.5171
Donor creatinine: missing (ref=mean donor creatinine*)	0.9134	1.0314	0.3758
Donor smoked in last six months: yes	0.1514	0.1964	0.4407
Donor used cocaine, IV drugs or other drugs in last six months: yes to any	0.2269	0.2331	0.3303
Hemodynamics PA (systolic): linear (ref=mean*)	-0.0012	0.0079	0.8817
Hemodynamics PA (systolic): missing (ref=mean*)	0.5664	0.1930	0.0033
Ischemia time: linear (ref=average time*)	0.0564	0.0639	0.3768
Ischemia time: missing (ref=average time*)	0.3136	0.1974	0.1122
Previous transplant of this organ type	-0.0690	0.4618	0.8812
Recipient angina/CAD at listing: angina, stable or stability unknown	0.4952	0.2878	0.0852
Recipient angina/CAD at listing: angina, unstable	-0.3610	1.0149	0.7221
Recipient angina/CAD at listing: missing	0.2091	0.5265	0.6913
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	-0.0600	0.4712	0.8987
Recipient medical condition: in ICU (ref=not hospitalized)	1.1640	0.4016	0.0038
Hemodynamics PA (mean) by diagnosis interaction: mean PA >30 and sarcoidosis	-0.1842	0.5020	0.7137
Hemodynamics PA (mean) by diagnosis interaction: mean PA missing and sarcoidosis	0.3176	0.3794	0.4025



* Ischemia time is centered on 4.53 hours; recipient age is centered on 49.64 ; recipient serum creatinine is centered on 0.92 mg/dl; donor serum creatinine is centered on 1.13 mg/dl; hemodynamics PA (systolic) is centered on 41.16 mm/Hg; hemodynamics PCW pressure is centered on 11.73 mm/Hg; distance between recipient and donor centers is centered on 180.51 miles.

Graft Survival Model Description
3 Years after Transplant
Organ: Lung
Adult (Age 12+)


Patient Characteristic Covariates	beta	standard error	p-value


Diagnosis: Emphysema/COPD and Alpha-1-Antitrypsin Deficiency (70.7% alive at 3 Years when all covariates=0.)
CMV mismatch: donor CMV positive, recipient CMV negative	0.0664	0.1343	0.6211
CMV mismatch: missing (donor or recipient CMV missing or unknown)	0.8571	0.5885	0.1453
Diagnosis: obliterative bronchiolitis or bronchiectasis	-0.0705	0.2606	0.7866
Distance between recipient and donor centers: miles (ref=mean distance*)	-0.0001	0.0003	0.8670
Distance between recipient and donor centers: missing (ref=mean distance*)	0.1283	0.1288	0.3190
Hemodynamics PCW pressure: 20+ (ref=mean*)	0.1522	1.0970	0.8897
Hemodynamics PCW pressure: linear (ref=mean*)	-0.0070	0.0130	0.5883
Hemodynamics PCW pressure: missing (ref=mean*)	0.1979	0.1257	0.1153
Previous transplant of this organ type	1.0649	0.3131	0.0007
Recipient age: years (ref=mean age*)	0.0236	0.0070	0.0007
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4105	0.2657	0.1222
Recipient medical condition: in ICU (ref=not hospitalized)	0.9112	0.2984	0.0023
Recipient six minute walk distance < 150 ft at listing: unknown or missing	0.3276	0.1564	0.0361
Recipient six minute walk distance < 150 ft at listing: yes	0.3214	0.1851	0.0825
Hemodynamics PA (mean) by diagnosis interaction: mean PA 30 or less and sarcoidosis	0.4318	0.4660	0.3541

Diagnosis: Primary Pulmonary Hypertension and Eisenmengers (62.9% alive at 3 Years when all covariates=0.)
Diagnosis: pulmonary vascular disease	0.4867	0.8085	0.5472
Donor BMI: 30+	-0.3022	0.6195	0.6258
Donor Hispanic/Latino	-1.5443	0.8014	0.0540
Donor age: 0-17	-0.2050	0.5291	0.6985
Donor age: 18-34	0.4044	0.4345	0.3519
Donor age: 50+	0.6421	0.8023	0.4235
Recipient creatinine: linear (ref=mean creatinine*)	1.0841	0.4381	0.0133
Recipient creatinine: missing (ref=mean creatinine*)	-1.3598	1.3120	0.3000
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.8994	0.6392	0.1594
Recipient medical condition: in ICU (ref=not hospitalized)	0.2332	1.0539	0.8249
Recipient on Ventilator	1.7513	1.2631	0.1656
Recipient race: Black	2.3500	0.7752	0.0024

Diagnosis: Cystic Fibrosis (64.1% alive at 3 Years when all covariates=0.)
Previous transplant of this organ type	2.7804	1.0773	0.0099
Recipient on Ventilator	0.9093	0.3728	0.0147
Recipient previous transfusions at listing: unknown or missing	-0.1374	0.2635	0.6021
Recipient previous transfusions at listing: yes	0.4223	0.3177	0.1838

Diagnosis: Idiopathic Pulmonary Fibrosis and not classified (57.2% alive at 3 Years when all covariates=0.)
ABO compatibility: compatible	0.0514	0.2584	0.8422
Diagnosis: not classified	-0.0647	0.3139	0.8368
Diagnosis: obliterative bronchiolitis (not retransplanted)	-0.1136	0.4512	0.8012
Diagnosis: pulmonary fibrosis other	0.2517	0.2044	0.2181
Donor CMV: missing (U, ND, I, C, or missing)	0.7442	0.5413	0.1692
Donor CMV: positive	0.1137	0.1540	0.4603
Donor age: 46+	0.3309	0.1877	0.0779
Donor creatinine: linear (ref=mean donor creatinine*)	0.1241	0.0492	0.0117
Donor creatinine: missing (ref=mean donor creatinine*)	1.1233	0.5280	0.0334
Donor smoked in last six months: yes	0.1558	0.1656	0.3468
Donor used cocaine, IV drugs or other drugs in last six months: yes to any	0.3306	0.2019	0.1014
Hemodynamics PA (systolic): linear (ref=mean*)	0.0054	0.0050	0.2770
Hemodynamics PA (systolic): missing (ref=mean*)	-0.2268	0.1851	0.2206
Previous transplant of this organ type	0.0484	0.4551	0.9154
Recipient angina/CAD at listing: angina, stable or stability unknown	0.3302	0.2402	0.1692
Recipient angina/CAD at listing: angina, unstable	2.7695	0.7588	0.0003
Recipient angina/CAD at listing: missing	-0.8361	0.5139	0.1038
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4356	0.3314	0.1887
Recipient medical condition: in ICU (ref=not hospitalized)	-0.1105	0.4039	0.7844
Recipient race: Black	0.4305	0.2170	0.0472
Hemodynamics PA (mean) by diagnosis interaction: mean PA >30 and sarcoidosis	-0.9785	0.5407	0.0703
Hemodynamics PA (mean) by diagnosis interaction: mean PA missing and sarcoidosis	-0.4995	0.6080	0.4114



* Ischemia time is centered on 4.53 hours; recipient age is centered on 49.64 ; recipient serum creatinine is centered on 0.92 mg/dl; donor serum creatinine is centered on 1.13 mg/dl; hemodynamics PA (systolic) is centered on 41.16 mm/Hg; hemodynamics PCW pressure is centered on 11.73 mm/Hg; distance between recipient and donor centers is centered on 180.51 miles.

Patient Survival Model Description
1 Month after First Transplant
Organ: Lung
Adult (Age 12+)


Patient Characteristic Covariates	beta	standard error	p-value


Diagnosis: Emphysema/COPD and Alpha-1-Antitrypsin Deficiency (95.8% alive at 1 Month when all covariates=0.)
CMV mismatch: donor CMV positive, recipient CMV negative	-0.0814	0.3314	0.8059
Diagnosis: obliterative bronchiolitis or bronchiectasis	0.8517	0.5517	0.1226
Distance between recipient and donor centers: miles (ref=mean distance*)	-0.0007	0.0007	0.3094
Donor race: Asian	0.4602	1.0202	0.6519
Donor race: Black	-0.0233	0.4061	0.9542
Hemodynamics PCW pressure: 20+ (ref=mean*)	-12.3320	601.9001	0.9837
Hemodynamics PCW pressure: linear (ref=mean*)	0.0445	0.0306	0.1462
Hemodynamics PCW pressure: missing (ref=mean*)	0.0842	0.2919	0.7731
Recipient age: years (ref=mean age*)	0.0162	0.0186	0.3831
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.7587	0.7319	0.2999
Recipient medical condition: in ICU (ref=not hospitalized)	1.2133	0.7524	0.1069
Recipient six minute walk distance < 150 ft at listing: unknown or missing	-0.2694	0.5260	0.6086
Recipient six minute walk distance < 150 ft at listing: yes	0.0979	0.4886	0.8412
Hemodynamics PA (mean) by diagnosis interaction: mean PA 30 or less and sarcoidosis	0.9218	1.0291	0.3704

Diagnosis: Primary Pulmonary Hypertension and Eisenmengers (89.1% alive at 1 Month when all covariates=0.)
Diagnosis: pulmonary vascular disease	0.4392	1.1049	0.6910
Donor race: Black	-0.3107	1.2677	0.8064
Recipient creatinine: linear (ref=mean creatinine*)	-0.9194	1.3802	0.5053
Recipient creatinine: missing (ref=mean creatinine*)	1.2701	1.2677	0.3164
Recipient on Ventilator	1.3355	1.0723	0.2130

Diagnosis: Cystic Fibrosis (93.6% alive at 1 Month when all covariates=0.)
Donor race: Black	0.4330	0.6735	0.5202
Donor race: Multi-racial, other, unknown or missing	-13.3705	1938.3080	0.9945
Recipient age: years (ref=mean age*)	0.0284	0.0305	0.3531
Recipient on Ventilator	2.1619	0.7957	0.0066
Recipient previous transfusions at listing: unknown or missing	-0.1963	0.7763	0.8004
Recipient previous transfusions at listing: yes	0.2849	1.0616	0.7884

Diagnosis: Idiopathic Pulmonary Fibrosis and not classified (96.8% alive at 1 Month when all covariates=0.)
ABO compatibility: compatible	-0.1784	0.6144	0.7715
Diagnosis: not classified	1.7318	0.4630	0.0002
Diagnosis: pulmonary fibrosis other	0.1350	0.5354	0.8009
Donor CMV: positive	-0.1427	0.3028	0.6375
Donor age: 46+	0.7006	0.3130	0.0252
Donor creatinine: linear (ref=mean donor creatinine*)	-0.0376	0.1530	0.8061
Donor creatinine: missing (ref=mean donor creatinine*)	-12.3471	1659.1257	0.9941
Donor smoked in last six months: yes	-0.1834	0.3665	0.6168
Donor used cocaine, IV drugs or other drugs in last six months: yes to any	-0.1993	0.4643	0.6677
Hemodynamics PA (systolic): linear (ref=mean*)	0.0277	0.0107	0.0095
Hemodynamics PA (systolic): missing (ref=mean*)	1.0265	0.3305	0.0019
Recipient age: 18-34 (ref=35-49)	0.4853	0.7907	0.5394
Recipient age: 50-64 (ref=35-49)	0.7152	0.3680	0.0519
Recipient age: 65+ (ref=35-49)	-0.0070	1.0764	0.9948
Recipient angina/CAD at listing: angina, stable or stability unknown	0.6505	0.5003	0.1935
Recipient angina/CAD at listing: angina, unstable	-12.5394	778.9091	0.9872
Recipient angina/CAD at listing: missing	-0.1568	1.0377	0.8799
Recipient race: Black	0.1440	0.4275	0.7362
Hemodynamics PA (mean) by diagnosis interaction: mean PA missing and sarcoidosis	0.5813	0.6137	0.3436



* Ischemia time is centered on 4.53 hours; recipient age is centered on 49.64 ; recipient serum creatinine is centered on 0.92 mg/dl; donor serum creatinine is centered on 1.13 mg/dl; hemodynamics PA (systolic) is centered on 41.16 mm/Hg; hemodynamics PCW pressure is centered on 11.73 mm/Hg; distance between recipient and donor centers is centered on 180.51 miles.

Patient Survival Model Description
1 Year after First Transplant
Organ: Lung
Adult (Age 12+)


Patient Characteristic Covariates	beta	standard error	p-value


Diagnosis: Emphysema/COPD and Alpha-1-Antitrypsin Deficiency (84.8% alive at 1 Year when all covariates=0.)
CMV mismatch: donor CMV positive, recipient CMV negative	0.1224	0.1602	0.4449
Diagnosis: lymphangioleiomyomatosis	-0.2311	0.6022	0.7012
Diagnosis: obliterative bronchiolitis or bronchiectasis	0.2736	0.3600	0.4472
Distance between recipient and donor centers: miles (ref=mean distance*)	-0.0001	0.0003	0.7969
Donor Hispanic/Latino	0.3468	0.2361	0.1419
Donor race: Asian	-0.1338	0.7141	0.8514
Donor race: Black	0.2141	0.1973	0.2777
Donor race: Multi-racial, other, unknown or missing	0.4063	0.7204	0.5727
Hemodynamics PCW pressure: 20+ (ref=mean*)	-10.7291	308.1120	0.9722
Hemodynamics PCW pressure: linear (ref=mean*)	-0.0076	0.0175	0.6626
Hemodynamics PCW pressure: missing (ref=mean*)	0.1355	0.1498	0.3659
Recipient age: years (ref=mean age*)	0.0111	0.0098	0.2592
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.0864	0.5095	0.8653
Recipient medical condition: in ICU (ref=not hospitalized)	0.6991	0.5945	0.2396
Recipient six minute walk distance < 150 ft at listing: unknown or missing	0.3930	0.2139	0.0661
Recipient six minute walk distance < 150 ft at listing: yes	-0.0218	0.2876	0.9397
Hemodynamics PA (mean) by diagnosis interaction: mean PA 30 or less and sarcoidosis	0.5234	0.5939	0.3781

Diagnosis: Primary Pulmonary Hypertension and Eisenmengers (79.3% alive at 1 Year when all covariates=0.)
Diagnosis: pulmonary vascular disease	0.7865	0.7870	0.3176
Donor BMI: 30+	0.0671	0.7584	0.9295
Donor age: 0-17	1.6110	0.4727	0.0007
Donor race: Black	-0.7355	0.7659	0.3369
Recipient creatinine: linear (ref=mean creatinine*)	0.4468	0.8314	0.5910
Recipient on Ventilator	1.5940	0.7803	0.0411

Diagnosis: Cystic Fibrosis (77.6% alive at 1 Year when all covariates=0.)
	1.3638	1.0684	0.2018
Donor age: 0-17	-0.0847	0.3935	0.8296
Donor age: 18-34	-0.3272	0.3702	0.3769
Donor age: 50+	0.3465	0.5514	0.5297
Donor race: Black	0.2816	0.4006	0.4822
Donor race: Multi-racial, other, unknown or missing	1.2587	0.7535	0.0948
Ischemia time: linear (ref=average time*)	-0.1230	0.1358	0.3650
Ischemia time: quadratic (ref=average time*)	0.0320	0.0260	0.2177
Ischemia time: missing (ref=average time*)	-0.1252	0.4289	0.7703
Recipient age: 12-17	-0.1419	0.5206	0.7851
Recipient age: 18-34 (ref=35-49)	-0.3440	0.3307	0.2983
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.1899	0.4689	0.6855
Recipient medical condition: in ICU (ref=not hospitalized)	1.1849	0.8526	0.1646
Recipient on Ventilator	0.6129	0.8829	0.4875
Recipient previous transfusions at listing: unknown or missing	-0.2286	0.3787	0.5461
Recipient previous transfusions at listing: yes	-1.1679	1.0185	0.2515

Diagnosis: Idiopathic Pulmonary Fibrosis and not classified (83.5% alive at 1 Year when all covariates=0.)
ABO compatibility: compatible	-0.2785	0.3707	0.4525
Diagnosis: not classified	0.6737	0.3406	0.0479
Diagnosis: obliterative bronchiolitis (not retransplanted)	-0.2043	0.5964	0.7319
Diagnosis: pulmonary fibrosis other	-0.0714	0.3221	0.8245
Donor CMV: positive	0.4204	0.1866	0.0242
Donor age: 46+	0.4337	0.1968	0.0275
Donor creatinine: linear (ref=mean donor creatinine*)	-0.0741	0.1269	0.5593
Donor creatinine: missing (ref=mean donor creatinine*)	1.1143	1.0228	0.2760
Donor smoked in last six months: yes	0.1851	0.1986	0.3514
Donor used cocaine, IV drugs or other drugs in last six months: yes to any	0.2003	0.2418	0.4073
Hemodynamics PA (systolic): linear (ref=mean*)	-0.0017	0.0077	0.8252
Hemodynamics PA (systolic): missing (ref=mean*)	0.5045	0.1952	0.0097
Recipient angina/CAD at listing: angina, stable or stability unknown	0.4413	0.2849	0.1215
Recipient angina/CAD at listing: angina, unstable	-0.3197	1.0149	0.7528
Recipient angina/CAD at listing: missing	0.6125	0.4657	0.1885
Hemodynamics PA (mean) by diagnosis interaction: mean PA >30 and sarcoidosis	-0.2095	0.4990	0.6745
Hemodynamics PA (mean) by diagnosis interaction: mean PA missing and sarcoidosis	0.3858	0.3772	0.3064



* Ischemia time is centered on 4.53 hours; recipient age is centered on 49.64 ; recipient serum creatinine is centered on 0.92 mg/dl; donor serum creatinine is centered on 1.13 mg/dl; hemodynamics PA (systolic) is centered on 41.16 mm/Hg; hemodynamics PCW pressure is centered on 11.73 mm/Hg; distance between recipient and donor centers is centered on 180.51 miles.

Patient Survival Model Description
3 Years after First Transplant
Organ: Lung
Adult (Age 12+)


Patient Characteristic Covariates	beta	standard error	p-value


Diagnosis: Emphysema/COPD and Alpha-1-Antitrypsin Deficiency (71.6% alive at 3 Years when all covariates=0.)
CMV mismatch: donor CMV positive, recipient CMV negative	0.0135	0.1406	0.9234
CMV mismatch: missing (donor or recipient CMV missing or unknown)	0.8080	0.5894	0.1704
Diagnosis: obliterative bronchiolitis or bronchiectasis	-0.2660	0.3149	0.3983
Distance between recipient and donor centers: miles (ref=mean distance*)	-0.0002	0.0003	0.6342
Distance between recipient and donor centers: missing (ref=mean distance*)	0.1407	0.1315	0.2846
Hemodynamics PCW pressure: 20+ (ref=mean*)	0.1503	1.0944	0.8907
Hemodynamics PCW pressure: linear (ref=mean*)	-0.0045	0.0129	0.7283
Hemodynamics PCW pressure: missing (ref=mean*)	0.2137	0.1298	0.0997
Recipient age: years (ref=mean age*)	0.0251	0.0076	0.0009
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4473	0.2886	0.1212
Recipient medical condition: in ICU (ref=not hospitalized)	0.6095	0.3925	0.1205
Recipient six minute walk distance < 150 ft at listing: unknown or missing	0.4711	0.1591	0.0031
Recipient six minute walk distance < 150 ft at listing: yes	0.2620	0.1987	0.1873
Hemodynamics PA (mean) by diagnosis interaction: mean PA 30 or less and sarcoidosis	0.5959	0.4290	0.1648

Diagnosis: Primary Pulmonary Hypertension and Eisenmengers (63.1% alive at 3 Years when all covariates=0.)
Diagnosis: pulmonary vascular disease	0.4677	0.8128	0.5650
Donor BMI: 30+	-0.2095	0.6186	0.7349
Donor Hispanic/Latino	-1.4928	0.7977	0.0613
Donor age: 0-17	-0.2511	0.5273	0.6339
Donor age: 18-34	0.3706	0.4357	0.3949
Donor age: 50+	0.6611	0.8025	0.4101
Recipient creatinine: linear (ref=mean creatinine*)	1.0001	0.4439	0.0242
Recipient creatinine: missing (ref=mean creatinine*)	-1.3939	1.3196	0.2908
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.5086	0.6345	0.4228
Recipient medical condition: in ICU (ref=not hospitalized)	0.2737	1.0550	0.7953
Recipient on Ventilator	1.6471	1.2609	0.1915
Recipient race: Black	2.3018	0.7755	0.0030

Diagnosis: Cystic Fibrosis (73.4% alive at 3 Years when all covariates=0.)
Ischemia time: linear (ref=average time*)	-0.0049	0.1179	0.9670
Ischemia time: quadratic (ref=average time*)	0.0109	0.0239	0.6480
Ischemia time: missing (ref=average time*)	0.6869	0.2824	0.0150
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.5162	0.2723	0.0581
Recipient medical condition: in ICU (ref=not hospitalized)	1.9078	0.6529	0.0035
Recipient on Ventilator	-0.6625	0.6838	0.3327
Recipient previous transfusions at listing: unknown or missing	-0.0219	0.2690	0.9352
Recipient previous transfusions at listing: yes	0.5524	0.3253	0.0894

Diagnosis: Idiopathic Pulmonary Fibrosis and not classified (65.0% alive at 3 Years when all covariates=0.)
ABO compatibility: compatible	-0.0983	0.2747	0.7204
ABO compatibility: incompatible	-0.6595	1.0275	0.5209
Diagnosis: not classified	-0.0408	0.3420	0.9050
Diagnosis: obliterative bronchiolitis (not retransplanted)	-0.0157	0.4926	0.9745
Diagnosis: pulmonary fibrosis other	0.4292	0.2053	0.0366
Donor CMV: missing (U, ND, I, C, or missing)	0.7520	0.6045	0.2135
Donor CMV: positive	0.1235	0.1554	0.4269
Donor age: 46+	0.3463	0.1868	0.0638
Donor creatinine: linear (ref=mean donor creatinine*)	0.1296	0.0490	0.0081
Donor creatinine: missing (ref=mean donor creatinine*)	0.8636	0.5857	0.1404
Donor smoked in last six months: yes	0.1466	0.1664	0.3781
Donor used cocaine, IV drugs or other drugs in last six months: yes to any	0.3110	0.2071	0.1333
Hemodynamics PA (systolic): linear (ref=mean*)	0.0058	0.0049	0.2355
Hemodynamics PA (systolic): missing (ref=mean*)	-0.2339	0.1952	0.2310
Recipient age: 18-34 (ref=35-49)	0.7048	0.3574	0.0486
Recipient age: 50-64 (ref=35-49)	0.3664	0.1877	0.0510
Recipient age: 65+ (ref=35-49)	0.6036	0.3056	0.0482
Recipient angina/CAD at listing: angina, stable or stability unknown	0.2252	0.2431	0.3543
Recipient angina/CAD at listing: angina, unstable	2.6331	0.7491	0.0004
Recipient angina/CAD at listing: missing	-1.3907	0.7157	0.0520
Hemodynamics PA (mean) by diagnosis interaction: mean PA >30 and sarcoidosis	-0.6219	0.5313	0.2418
Hemodynamics PA (mean) by diagnosis interaction: mean PA missing and sarcoidosis	-0.4331	0.6166	0.4825



* Ischemia time is centered on 4.53 hours; recipient age is centered on 49.64 ; recipient serum creatinine is centered on 0.92 mg/dl; donor serum creatinine is centered on 1.13 mg/dl; hemodynamics PA (systolic) is centered on 41.16 mm/Hg; hemodynamics PCW pressure is centered on 11.73 mm/Hg; distance between recipient and donor centers is centered on 180.51 miles.

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