ustransplant.org - Research Resources - Analytic Conventions - Model Description (Liver

Research Resources: Analytic Conventions - Model Description (Liver - Living)

Model Descriptions on This Page

Graft Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Patient Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Living Donor Graft Survival Model Description
1 Month after Transplant
Organ: Liver
Adult (Age 18+)

92.2% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	0.1909	0.2820	0.4985
ABO compatibility: incompatible (ref=equal)	-14.4905	1758.4798	0.9934
Creatinine > 2	0.2500	0.7255	0.7304
Diagnosis: AHN*	1.0559	0.4228	0.0125
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	0.5661	0.2579	0.0282
Diagnosis: Malignant Neoplasms*	-0.7654	0.7293	0.2939
Diagnosis: Metabolic Diseases*	-13.4177	561.5847	0.9809
Diagnosis: Other/Missing*	0.8954	0.4834	0.0640
Donor age: 18-34 (ref=35-49)	0.1675	0.2448	0.4939
Donor age: 50-64 (ref=35-49)	0.3276	0.3492	0.3482
Donor age: 65+ (ref=35-49)	-14.4716	2485.0082	0.9954
Donor female	0.3299	0.2298	0.1511
Ischemia time: linear (ref=average time**)	0.0339	0.0404	0.4012
Ischemia time: missing (ref=average time**)	-0.4674	0.3841	0.2237
Ischemia time: quadratic (ref=average time**)	-0.0013	0.0023	0.5659
Previous transplant of this organ type	1.7434	0.5253	0.0009
Recipient on life support	1.2946	0.5479	0.0181


* Reference for diagnosis group is non-cholestatic cirrhosis.
** Ischemia time is centered on 8.01 hours.

Living Donor Graft Survival Model Description
1 Year after Transplant
Organ: Liver
Adult (Age 18+)

80.9% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	0.0927	0.2166	0.6688
ABO compatibility: incompatible (ref=equal)	-12.2450	473.7775	0.9794
Creatinine > 2	0.7644	0.4029	0.0578
Diagnosis: AHN*	0.4360	0.3828	0.2547
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	0.2723	0.2064	0.1871
Diagnosis: Malignant Neoplasms*	-0.3121	0.4145	0.4514
Diagnosis: Metabolic Diseases*	0.4581	0.4348	0.2921
Diagnosis: Other/Missing*	0.3102	0.4599	0.5000
Donor age: 18-34 (ref=35-49)	0.2962	0.4263	0.4872
Donor age: 50-64 (ref=35-49)	-2.1999	1.7284	0.2031
Donor age: 65+ (ref=35-49)	-12.6166	578.1993	0.9826
Donor female	0.2900	0.1743	0.0961
Donor race: Asian (ref=White)	0.9619	0.7787	0.2168
Donor race: Black (ref=White)	-0.8651	0.6834	0.2055
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.5240	0.4397	0.2334
Ischemia time: linear (ref=average time**)	0.0486	0.0473	0.3049
Ischemia time: missing (ref=average time**)	-0.6234	0.3752	0.0966
Ischemia time: quadratic (ref=average time**)	-0.0042	0.0026	0.1043
Previous transplant of this organ type	1.4648	0.4692	0.0018
Recipient age: 18-34 (ref=35-49)	-0.1827	0.3346	0.5851
Recipient age: 50-64 (ref=35-49)	0.0495	0.2096	0.8133
Recipient age: 65+ (ref=35-49)	-0.3020	0.4223	0.4746
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.3988	0.2214	0.0716
Recipient medical condition: in ICU (ref=not hospitalized)	0.8672	0.3712	0.0195
Recipient on life support	1.2513	0.4625	0.0068
Recipient race: Asian (ref=White)	-0.9607	1.1245	0.3929
Recipient race: Black (ref=White)	1.6514	0.6717	0.0139
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.5971	0.7825	0.4454
Donor age by ischemia time interaction: 18-34 and ischemia time (ref=35-49 and avg ischemia time**)	0.0549	0.0646	0.3958
Donor age by ischemia time interaction: 18-34 and missing ischemia time (ref=35-49 and avg ischemia time**)	-0.2329	0.5097	0.6477
Donor age by ischemia time interaction: 50-64 and ischemia time (ref=35-49 and avg ischemia time**)	-0.4015	0.2552	0.1157
Donor age by ischemia time interaction: 50-64 and missing ischemia time (ref=35-49 and avg ischemia time**)	2.8536	1.7657	0.1061
Donor age by ischemia time interaction: 65+ and ischemia time (ref=35-49 and avg ischemia time**)	0.0076	113.4114	0.9999
Recipient age by recipient race interaction: 18-34 and Asian (ref=35-49 and White)	-12.3189	1159.4931	0.9915
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	0.2904	0.9261	0.7539
Recipient age by recipient race interaction: 18-34 and multi-racial/other/unknown/missing (ref=35-49 and White)	1.0771	1.3010	0.4077
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	-0.3033	1.2693	0.8112
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-0.2322	0.7460	0.7556
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	0.5960	0.8418	0.4789
Recipient age by recipient race interaction: 65+ and Asian (ref=35-49 and White)	1.9694	1.5931	0.2164
Recipient age by recipient race interaction: 65+ and multi-racial/other/unknown/missing (ref=35-49 and White)	1.6013	1.1224	0.1537


* Reference for diagnosis group is non-cholestatic cirrhosis.
** Ischemia time is centered on 8.01 hours.

Living Donor Graft Survival Model Description
3 Years after Transplant
Organ: Liver
Adult (Age 18+)

64.3% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	-0.1567	1.1252	0.8892
Creatinine > 2	1.2884	0.7566	0.0886
Diagnosis: AHN*	1.5397	0.5611	0.0061
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-0.8940	0.5593	0.1100
Diagnosis: Malignant Neoplasms*	0.2672	0.4671	0.5672
Diagnosis: Metabolic Diseases*	-14.9809	941.6854	0.9873
Diagnosis: Other/Missing*	-0.7507	0.7406	0.3107
Donor age: 18-34 (ref=35-49)	-0.9876	0.3757	0.0086
Donor age: 50-64 (ref=35-49)	0.2475	0.4685	0.5973
Donor female	0.1981	0.3192	0.5347
Donor race: Asian (ref=White)	2.0867	1.4508	0.1503
Donor race: Black (ref=White)	0.7098	1.3480	0.5985
Donor race: Multi-racial, other, unknown or missing (ref=White)	-1.5133	1.0813	0.1617
Ischemia time: linear (ref=average time**)	0.0028	0.0480	0.9532
Ischemia time: missing (ref=average time**)	0.0230	0.5318	0.9655
Ischemia time: quadratic (ref=average time**)	-0.0042	0.0034	0.2119
Previous transplant of this organ type	-0.2753	0.7097	0.6981
Recipient age: 18-34 (ref=35-49)	-0.2688	0.7942	0.7350
Recipient age: 50-64 (ref=35-49)	0.7469	0.3621	0.0391
Recipient age: 65+ (ref=35-49)	0.9252	0.6824	0.1751
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4515	0.4507	0.3165
Recipient medical condition: in ICU (ref=not hospitalized)	0.3174	1.1106	0.7750
Recipient on life support	-0.0528	1.1273	0.9626
Recipient race: Asian (ref=White)	-14.2442	1230.9335	0.9908
Recipient race: Black (ref=White)	1.9375	1.3740	0.1585
Recipient race: Multi-racial, other, unknown or missing (ref=White)	2.8046	1.4105	0.0468
Donor age by ABO compatibility interaction: 18-34 and compatible (ref=35-49 and equal)	-1.0703	1.5096	0.4783
Donor age by ABO compatibility interaction: 50-64 and compatible (ref=35-49 and equal)	-13.2609	2244.7556	0.9953
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	1.1457	1.3743	0.4045
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	14.4465	1230.9341	0.9906
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-17.1025	1323.9583	0.9897
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	1.7303	2.1178	0.4139
Recipient age by recipient race interaction: 65+ and Black (ref=35-49 and White)	-0.8852	1.4724	0.5477


* Reference for diagnosis group is non-cholestatic cirrhosis.
** Ischemia time is centered on 8.01 hours.

Living Donor Graft Survival Model Description
1 Month after Transplant
Organ: Liver
Pediatric (Age 0-17)

98.2% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	0.2895	0.7177	0.6867
ABO compatibility: incompatible (ref=equal)	-17.6117	21439.0633	0.9993
Donor age: 18-34 (ref=35-49)	-0.5630	0.5622	0.3166
Donor age: 50-64 (ref=35-49)	2.3102	1.1828	0.0508
Ischemia time: linear (ref=average time**)	-0.1807	0.1662	0.2769
Ischemia time: missing (ref=average time**)	1.9017	1.1938	0.1112
Ischemia time: quadratic (ref=average time**)	0.0035	0.0083	0.6710
Previous transplant of this organ type	-0.4279	1.0690	0.6890
Recipient age: 0-1 (ref=2-10)	0.2285	0.5025	0.6493
Recipient age: 11-17 (ref=2-10)	0.1863	0.6748	0.7825
Recipient on life support	5.3617	1.9137	0.0051
Recipient race: Asian (ref=White)	-18.4182	19138.0933	0.9992
Recipient race: Black (ref=White)	0.6774	0.8526	0.4269
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-19.5055	20113.9895	0.9992
Donor age by ABO compatibility interaction: 18-34 and compatible (ref=35-49 and equal)	1.8785	0.9184	0.0408
Donor age by ABO compatibility interaction: 18-34 and incompatible (ref=35-49 and equal)	19.4344	21439.0633	0.9993
Ischemia time by recipient on life support interaction: ischemia time and yes (ref=avg time** and no)	0.5206	0.3033	0.0861
Ischemia time by recipient on life support interaction: missing ischemia time and yes (ref=avg time** and no)	-4.2190	2.0704	0.0416
Recipient age by recipient race interaction: 0-1 and Asian (ref=2-10 and white)	0.1132	20724.3551	1.0000
Recipient age by recipient race interaction: 0-1 and Black (ref=2-10 and white)	-0.4684	1.0813	0.6648
Recipient age by recipient race interaction: 0-1 and multi-racial/other/unknown/missing (ref=2-10 and white)	-15.7763	20148.9236	0.9994
Recipient age by recipient race interaction: 11-17 and Black (ref=2-10 and White)	0.9856	1.4356	0.4924
Recipient age by recipient race interaction: 11-17 and multi-racial/other/unknown/missing (ref=2-10 and White)	1.6739	41054.7040	1.0000


* Reference for diagnosis group is biliary atresia.
** Ischemia time is centered on 8.01 hours.

Living Donor Graft Survival Model Description
1 Year after Transplant
Organ: Liver
Pediatric (Age 0-17)

73.7% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	1.2532	0.3364	0.0002
ABO compatibility: incompatible (ref=equal)	1.4793	1.0345	0.1527
Donor age: 18-34 (ref=35-49)	-1.0492	0.4568	0.0216
Donor age: 50-64 (ref=35-49)	-12.2950	850.3037	0.9885
Previous transplant of this organ type	-0.0573	0.7437	0.9385
Recipient age: 0-1 (ref=2-10)	-1.8863	0.5441	0.0005
Recipient age: 11-17 (ref=2-10)	-0.7703	0.5118	0.1323
Recipient on life support	1.6373	0.3022	<0.0001
Recipient age by donor age interaction: 0-1 and 18-34 (ref=2-10 and 35-49)	2.0717	0.6835	0.0024
Recipient age by donor age interaction: 0-1 and 50-64 (ref=2-10 and 35-49)	15.2745	850.3044	0.9857
Recipient age by donor age interaction: 11-17 and 18-34 (ref=2-10 and 35-49)	2.1090	0.9477	0.0261


* Reference for diagnosis group is biliary atresia.
** Ischemia time is centered on 8.01 hours.

Living Donor Graft Survival Model Description
3 Years after Transplant
Organ: Liver
Pediatric (Age 0-17)

77.9% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	0.5906	0.4572	0.1964
ABO compatibility: incompatible (ref=equal)	1.1947	0.7652	0.1185
Creatinine > 2	1.2463	1.3316	0.3493
Diagnosis: AHN*	-0.0444	0.5098	0.9306
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-0.0236	1.0798	0.9825
Diagnosis: Malignant Neoplasms*	0.5679	0.6952	0.4140
Diagnosis: Metabolic Diseases*	0.1493	0.6055	0.8053
Diagnosis: Non-Cholestatic Cirrhosis*	0.5096	0.8397	0.5439
Diagnosis: Other/Missing*	-0.1640	0.4908	0.7382
Donor age: 18-34 (ref=35-49)	-0.2668	0.3718	0.4730
Donor age: 50-64 (ref=35-49)	1.2918	1.0537	0.2202
Previous transplant of this organ type	0.3849	0.5569	0.4895
Recipient age: 0-1 (ref=2-10)	0.0069	0.4339	0.9873
Recipient age: 11-17 (ref=2-10)	-1.3786	1.3199	0.2963
Recipient on life support	0.8687	0.4788	0.0696


* Reference for diagnosis group is biliary atresia.
** Ischemia time is centered on 8.01 hours.

Living Donor Patient Survival Model Description
1 Month after First Transplant
Organ: Liver
Adult (Age 18+)

100.0% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Creatinine > 2	0.1906	1.0506	0.8560
Diagnosis: AHN*	1.8633	0.5455	0.0006
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-0.3026	0.6504	0.6418
Diagnosis: Malignant Neoplasms*	0.4839	0.8055	0.5480
Diagnosis: Metabolic Diseases*	-13.4199	1281.9811	0.9916
Diagnosis: Other/Missing*	1.8443	0.6990	0.0083
Ischemia time: linear (ref=average time**)	-1.7030	1.6307	0.2963
Ischemia time: missing (ref=average time**)	3.4716	4.6911	0.4593
Ischemia time: quadratic (ref=average time**)	-0.1759	0.1411	0.2125
Recipient age: 18-34 (ref=35-49)	0.1489	0.9042	0.8692
Recipient age: 50-64 (ref=35-49)	1.1305	0.5634	0.0448
Recipient age: 65+ (ref=35-49)	0.8627	0.8924	0.3337
Recipient on life support	1.6683	0.7768	0.0317


* Reference for diagnosis group is non-cholestatic cirrhosis.
** Ischemia time is centered on 8.01 hours.

Living Donor Patient Survival Model Description
1 Year after First Transplant
Organ: Liver
Adult (Age 18+)

89.3% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Creatinine > 2	1.2378	0.4520	0.0062
Diagnosis: AHN*	0.6155	0.4258	0.1483
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-0.7170	0.3479	0.0393
Diagnosis: Malignant Neoplasms*	0.1070	0.4204	0.7992
Diagnosis: Metabolic Diseases*	0.3064	0.6001	0.6096
Diagnosis: Other/Missing*	0.0692	0.5523	0.9003
Donor age: 18-34 (ref=35-49)	0.1262	0.2419	0.6018
Donor age: 50-64 (ref=35-49)	0.6223	0.3250	0.0555
Donor age: 65+ (ref=35-49)	-13.8390	995.8754	0.9889
Ischemia time: linear (ref=average time**)	0.0794	0.0347	0.0222
Ischemia time: missing (ref=average time**)	-0.3208	0.3241	0.3222
Ischemia time: quadratic (ref=average time**)	-0.0024	0.0018	0.1753
Recipient age: 18-34 (ref=35-49)	-0.4922	0.5631	0.3821
Recipient age: 50-64 (ref=35-49)	0.4095	0.2780	0.1408
Recipient age: 65+ (ref=35-49)	0.4531	0.4501	0.3140
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.3285	0.2796	0.2399
Recipient medical condition: in ICU (ref=not hospitalized)	-0.1642	0.5746	0.7750
Recipient on life support	2.1829	0.6168	0.0004
Recipient race: Asian (ref=White)	0.1352	1.0363	0.8962
Recipient race: Black (ref=White)	1.3206	0.5694	0.0204
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.2572	1.0318	0.8032
Recipient age by recipient race interaction: 18-34 and Asian (ref=35-49 and White)	-12.8316	3082.7082	0.9967
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	1.6160	1.0638	0.1288
Recipient age by recipient race interaction: 18-34 and multi-racial/other/unknown/missing (ref=35-49 and White)	-11.9703	1368.8176	0.9930
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	0.0282	1.2046	0.9813
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-0.0845	0.8334	0.9192
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	0.1442	1.1561	0.9007
Recipient age by recipient race interaction: 65+ and Asian (ref=35-49 and White)	-13.9286	1054.6419	0.9895
Recipient age by recipient race interaction: 65+ and multi-racial/other/unknown/missing (ref=35-49 and White)	0.7349	1.5049	0.6253


* Reference for diagnosis group is non-cholestatic cirrhosis.
** Ischemia time is centered on 8.01 hours.

Living Donor Patient Survival Model Description
3 Years after First Transplant
Organ: Liver
Adult (Age 18+)

84.1% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Creatinine > 2	0.8949	0.9242	0.3329
Diagnosis: AHN*	1.4687	0.7086	0.0382
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-0.6539	0.6391	0.3062
Diagnosis: Malignant Neoplasms*	0.3923	0.4698	0.4037
Diagnosis: Metabolic Diseases*	-15.0052	1306.9626	0.9908
Diagnosis: Other/Missing*	-0.4651	0.8756	0.5953
Donor age: 18-34 (ref=35-49)	-0.1280	0.7191	0.8587
Donor age: 50-64 (ref=35-49)	0.9344	0.8550	0.2745
Donor race: Asian (ref=White)	2.4238	1.4821	0.1020
Donor race: Black (ref=White)	2.7930	1.3092	0.0329
Donor race: Multi-racial, other, unknown or missing (ref=White)	-0.9115	1.0617	0.3906
Ischemia time: linear (ref=average time**)	-0.0312	0.0537	0.5609
Ischemia time: missing (ref=average time**)	0.2626	0.5927	0.6577
Ischemia time: quadratic (ref=average time**)	-0.0022	0.0035	0.5302
Recipient age: 18-34 (ref=35-49)	0.3648	1.2115	0.7633
Recipient age: 50-64 (ref=35-49)	1.2891	0.5432	0.0176
Recipient age: 65+ (ref=35-49)	0.8515	1.1142	0.4447
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.1956	0.4678	0.6758
Recipient medical condition: in ICU (ref=not hospitalized)	1.0305	1.1750	0.3804
Recipient on life support	-0.3675	1.3232	0.7812
Recipient race: Asian (ref=White)	-14.6328	2261.1559	0.9948
Recipient race: Black (ref=White)	-15.5266	1303.9787	0.9905
Recipient race: Multi-racial, other, unknown or missing (ref=White)	1.7961	1.5842	0.2569
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	-0.2658	1.5307	0.8622
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	-0.3081	1.9438	0.8741
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	-1.2973	0.8533	0.1284
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	-1.0511	1.1059	0.3419
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	0.8527	1.4501	0.5565
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	13.9170	1303.9787	0.9915
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	15.2862	2261.1562	0.9946
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-2.1517	2233.8667	0.9992
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	-16.4242	2602.5366	0.9950
Recipient age by recipient race interaction: 65+ and Black (ref=35-49 and White)	13.7423	1303.9786	0.9916


* Reference for diagnosis group is non-cholestatic cirrhosis.
** Ischemia time is centered on 8.01 hours.

Living Donor Patient Survival Model Description
1 Month after First Transplant
Organ: Liver
Pediatric (Age 0-17)

97.1% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: AHN*	-0.4216	0.9879	0.6696
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-16.7575	6665.0720	0.9980
Diagnosis: Malignant Neoplasms*	-15.4579	2020.0885	0.9939
Diagnosis: Metabolic Diseases*	-0.3676	1.4869	0.8047
Diagnosis: Non-Cholestatic Cirrhosis*	-0.0160	1.4054	0.9909
Diagnosis: Other/Missing*	0.1470	0.8111	0.8562
Ischemia time: linear (ref=average time**)	-0.1228	0.8625	0.8868
Ischemia time: missing (ref=average time**)	0.3296	2.3123	0.8867
Ischemia time: quadratic (ref=average time**)	-0.0256	0.0993	0.7962
Recipient age: 0-1 (ref=2-10)	-0.2258	0.7710	0.7697
Recipient age: 11-17 (ref=2-10)	0.9536	1.1656	0.4133
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	-5.3141	5.8442	0.3632
Recipient medical condition: in ICU (ref=not hospitalized)	-6.1145	5.2146	0.2410
Recipient on life support	2.1616	1.0413	0.0379
Recipient race: Asian (ref=White)	-16.3440	4921.8761	0.9974
Recipient race: Black (ref=White)	0.6443	1.5130	0.6702
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-17.7009	5403.1044	0.9974
Ischemia time by recipient medical condition interaction: ischemia time and hospitalized not in ICU (ref=avg time** and not hospitalized)	-1.0897	0.9200	0.2362
Ischemia time by recipient medical condition interaction: ischemia time and in ICU (ref=avg time** and not hospitalized)	-1.0306	0.8565	0.2289
Ischemia time by recipient medical condition interaction: missing ischemia time and hospitalized not in ICU (ref=avg time** and not hospitalized)	-10.5856	4672.0835	0.9982
Ischemia time by recipient medical condition interaction: missing ischemia time and in ICU (ref=avg time** and not hospitalized)	6.6060	5.4485	0.2253
Recipient age by recipient race interaction: 0-1 and Asian (ref=2-10 and white)	0.8003	5857.2716	0.9999
Recipient age by recipient race interaction: 0-1 and Black (ref=2-10 and white)	-0.9139	1.8597	0.6232
Recipient age by recipient race interaction: 0-1 and multi-racial/other/unknown/missing (ref=2-10 and white)	1.7865	6209.4098	0.9998
Recipient age by recipient race interaction: 11-17 and Black (ref=2-10 and White)	-17.6518	5588.8335	0.9975
Recipient age by recipient race interaction: 11-17 and multi-racial/other/unknown/missing (ref=2-10 and White)	2.5009	15629.9496	0.9999


* Reference for diagnosis group is biliary atresia.
** Ischemia time is centered on 8.01 hours.

Living Donor Patient Survival Model Description
1 Year after First Transplant
Organ: Liver
Pediatric (Age 0-17)

88.1% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

ABO compatibility: compatible (ref=equal)	0.4843	0.3769	0.1989
ABO compatibility: incompatible (ref=equal)	1.4919	1.0421	0.1523
Diagnosis: AHN*	0.2111	0.5031	0.6748
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-14.0689	1095.0998	0.9897
Diagnosis: Malignant Neoplasms*	-0.2116	0.7654	0.7822
Diagnosis: Metabolic Diseases*	-0.0926	0.7693	0.9042
Diagnosis: Non-Cholestatic Cirrhosis*	-0.5103	0.7761	0.5108
Diagnosis: Other/Missing*	-0.3458	0.4920	0.4822
Donor Hispanic/Latino	-0.2217	0.4923	0.6525
Recipient on life support	1.6011	0.4267	0.0002


* Reference for diagnosis group is biliary atresia.
** Ischemia time is centered on 8.01 hours.

Living Donor Patient Survival Model Description
3 Years after First Transplant
Organ: Liver
Pediatric (Age 0-17)

99.8% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Creatinine > 2	-2.5582	4049.7414	0.9995
Diagnosis: AHN*	0.3377	0.6041	0.5762
Diagnosis: Cholestatic Liver Disease/Cirrhosis*	-14.0371	1873.6359	0.9940
Diagnosis: Malignant Neoplasms*	0.9208	0.8331	0.2691
Diagnosis: Metabolic Diseases*	-0.5745	1.0633	0.5890
Diagnosis: Non-Cholestatic Cirrhosis*	1.1105	1.2178	0.3618
Diagnosis: Other/Missing*	0.5417	0.6647	0.4151
Donor age: 18-34 (ref=35-49)	1.9792	3.2622	0.5440
Donor age: 50-64 (ref=35-49)	-7.1600	43022.9293	0.9999
Ischemia time: linear (ref=average time**)	-0.5566	0.3985	0.1625
Ischemia time: missing (ref=average time**)	2.8867	2.8507	0.3112
Ischemia time: quadratic (ref=average time**)	0.0100	0.0110	0.3629
Recipient age: 0-1 (ref=2-10)	0.5348	0.5913	0.3658
Recipient age: 11-17 (ref=2-10)	-13.4323	1754.7970	0.9939
Recipient on life support	2.0346	0.5851	0.0005
Donor age by ischemia time interaction: 18-34 and ischemia time (ref=35-49 and avg ischemia time**)	0.4195	0.4844	0.3865
Donor age by ischemia time interaction: 18-34 and missing ischemia time (ref=35-49 and avg ischemia time**)	-0.0080	3.4778	0.9982
Donor age by ischemia time interaction: 50-64 and ischemia time (ref=35-49 and avg ischemia time**)	1.1956	6584.6177	0.9999


* Reference for diagnosis group is biliary atresia.
** Ischemia time is centered on 8.01 hours.

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