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Research Resources: Analytic Conventions - Model Description (Kidney)

Model Descriptions on This Page

Graft Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Patient Survival Model Description

Adult (Age 18+)

Graft Survival Model Description
1 Month after Transplant
Organ: Kidney
Adult (Age 18+)

97.5% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.2820	0.2680	0.2927
Diagnosis: Diabetes*	0.0379	0.0989	0.7012
Diagnosis: Hypertensive Nephrosclerosis*	0.1146	0.1023	0.2626
Diagnosis: Other/Missing*	0.2833	0.1138	0.0128
Diagnosis: Polycystic Kidney Disease*	-0.1959	0.1404	0.1628
Diagnosis: Renovascular & Other Vascular Diseases*	-0.1875	0.1663	0.2595
Diagnosis: Tubular and Interstitial Diseases*	0.2369	0.1492	0.1122
Donor Hispanic/Latino	0.2219	0.0965	0.0216
Donor age: 0-17 (ref=35-49)	-0.1535	0.2027	0.4489
Donor age: 18-34 (ref=35-49)	0.0048	0.1376	0.9721
Donor age: 50-64 (ref=35-49)	0.1318	0.1473	0.3709
Donor age: 65+ (ref=35-49)	0.3433	0.3477	0.3234
Donor history of hypertension	0.2412	0.0969	0.0128
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.0646	0.4136	0.8759
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.0116	0.1299	0.9290
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.2180	0.0912	0.0168
Donor: cadaveric COD other (ref=COD Head trauma)	-0.2826	0.2750	0.3040
Donor: living (ref=cadaveric - COD Head trauma)	-0.1009	0.1021	0.3230
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.2440	0.0973	0.0121
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0790	0.0242	0.0011
HLA mismatch: missing (ref=3.5 mismatch)	0.7039	0.2727	0.0098
Ischemia time: linear (ref=average time**)	0.0071	0.0054	0.1869
Ischemia time: missing (ref=average time**)	-0.1948	0.0724	0.0071
Ischemia time: quadratic (ref=average time**)	0.0001	0.0003	0.7832
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.2169	0.1343	0.1063
Peak PRA: 10-79 (ref=<10)	0.1303	0.1101	0.2366
Peak PRA: 80-100 (ref=<10)	0.7407	0.1472	<0.0001
Peak PRA: missing (ref=<10)	-0.0612	0.5137	0.9052
Previous transplant of this organ type	0.1334	0.1337	0.3184
Recipient age: 18-34 (ref=35-49)	0.0843	0.1541	0.5843
Recipient age: 50-64 (ref=35-49)	0.1376	0.1270	0.2784
Recipient age: 65+ (ref=35-49)	0.3895	0.1731	0.0245
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.1748	0.1714	0.3079
Recipient female	0.2640	0.0765	0.0006
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4967	0.1832	0.0067
Recipient medical condition: in ICU (ref=not hospitalized)	1.9079	0.3074	<0.0001
Transplant procedure type en-bloc or double	0.4301	0.1622	0.0080
Year of ESRD treatment: missing (ref=years 3-5)	1.8894	0.2681	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.2984	0.0928	0.0013
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.0110	0.0892	0.9019
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.0111	0.0984	0.9105
donor serum creatinine>1.5 1=yes,0=no	0.2236	0.1026	0.0294
Recipient age by donor age interaction: 18-34 and 0-17 (ref=35-49 and 35-49)	0.2726	0.2938	0.3535
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	-0.1077	0.2178	0.6210
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	-0.2430	0.2526	0.3362
Recipient age by donor age interaction: 18-34 and 65+ (ref=35-49 and 35-49)	0.7288	0.5401	0.1772
Recipient age by donor age interaction: 50-64 and 0-17 (ref=35-49 and 35-49)	0.1227	0.2728	0.6530
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	-0.0291	0.1917	0.8792
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	-0.0645	0.1862	0.7289
Recipient age by donor age interaction: 50-64 and 65+ (ref=35-49 and 35-49)	-0.2854	0.4053	0.4813
Recipient age by donor age interaction: 65+ and 0-17 (ref=35-49 and 35-49)	-0.8780	0.5562	0.1145
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	-0.1255	0.2884	0.6635
Recipient age by donor age interaction: 65+ and 50-64 (ref=35-49 and 35-49)	-0.2098	0.2546	0.4098
Recipient age by donor age interaction: 65+ and 65+ (ref=35-49 and 35-49)	-0.3177	0.4221	0.4517
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	0.1470	0.2498	0.5561
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.3973	0.2551	0.1193
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0991	0.3690	0.7882
Recipient sex by peak PRA interaction: female and 10-79 (ref=male and <10)	0.0045	0.1486	0.9759
Recipient sex by peak PRA interaction: female and 80+ (ref=male and <10)	-0.4415	0.1873	0.0184
Recipient sex by peak PRA interaction: female and missing (ref=male and <10)	-0.6644	0.8705	0.4453


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Graft Survival Model Description
1 Year after Transplant
Organ: Kidney
Adult (Age 18+)

92.7% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.1316	0.2187	0.5473
Diagnosis: Diabetes*	0.1793	0.0630	0.0044
Diagnosis: Hypertensive Nephrosclerosis*	0.1839	0.0669	0.0060
Diagnosis: Other/Missing*	0.2003	0.0771	0.0094
Diagnosis: Polycystic Kidney Disease*	-0.3170	0.0959	0.0010
Diagnosis: Renovascular & Other Vascular Diseases*	0.0201	0.1000	0.8406
Diagnosis: Tubular and Interstitial Diseases*	0.1695	0.1021	0.0970
Donor Hispanic/Latino	0.1069	0.0666	0.1087
Donor age: 0-17 (ref=35-49)	-0.1477	0.0809	0.0679
Donor age: 18-34 (ref=35-49)	-0.2157	0.0566	0.0001
Donor age: 50-64 (ref=35-49)	0.0998	0.0602	0.0975
Donor age: 65+ (ref=35-49)	0.3542	0.1112	0.0014
Donor history of hypertension	0.1546	0.0614	0.0118
Donor race: Asian (ref=White)	0.1090	0.1349	0.4190
Donor race: Black (ref=White)	0.1838	0.0621	0.0031
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.4815	0.1626	0.0031
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.1269	0.2618	0.6277
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0236	0.0856	0.7827
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.2158	0.0582	0.0002
Donor: cadaveric COD other (ref=COD Head trauma)	0.0508	0.1502	0.7351
Donor: living (ref=cadaveric - COD Head trauma)	-0.2888	0.0671	<0.0001
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.2559	0.0647	0.0001
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0668	0.0157	<0.0001
HLA mismatch: missing (ref=3.5 mismatch)	0.2899	0.2154	0.1784
Ischemia time: linear (ref=average time**)	0.0057	0.0036	0.1074
Ischemia time: missing (ref=average time**)	-0.0815	0.0453	0.0719
Ischemia time: quadratic (ref=average time**)	0.0002	0.0001	0.0974
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1850	0.0834	0.0265
Peak PRA: 10-79 (ref=<10)	0.0509	0.0681	0.4548
Peak PRA: 80-100 (ref=<10)	0.5315	0.0982	<0.0001
Peak PRA: missing (ref=<10)	-0.0192	0.3410	0.9550
Previous transplant of this organ type	0.1734	0.0904	0.0551
Recipient age: 18-34 (ref=35-49)	0.0462	0.0661	0.4845
Recipient age: 50-64 (ref=35-49)	0.2586	0.0510	<0.0001
Recipient age: 65+ (ref=35-49)	0.5146	0.0677	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.1959	0.1212	0.1060
Recipient female	0.0052	0.0507	0.9181
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4317	0.1244	0.0005
Recipient medical condition: in ICU (ref=not hospitalized)	1.3421	0.2910	<0.0001
Recipient race: Asian (ref=White)	-0.2620	0.1119	0.0193
Recipient race: Black (ref=White)	0.0383	0.0516	0.4581
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.0668	0.1342	0.6188
Year of ESRD treatment: missing (ref=years 3-5)	1.5212	0.2282	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.3375	0.0607	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.1224	0.0582	0.0354
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.0163	0.0638	0.7983
donor serum creatinine>1.5 1=yes,0=no	0.1015	0.0683	0.1369
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0957	0.1890	0.6125
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0184	0.1559	0.9060
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0994	0.2262	0.6604
Recipient sex by peak PRA interaction: female and 10-79 (ref=male and <10)	0.0945	0.0969	0.3292
Recipient sex by peak PRA interaction: female and 80+ (ref=male and <10)	-0.2790	0.1284	0.0297
Recipient sex by peak PRA interaction: female and missing (ref=male and <10)	0.1090	0.5074	0.8300


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Graft Survival Model Description
3 Years after Transplant
Organ: Kidney
Adult (Age 18+)

87.2% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.1449	0.1312	0.2692
Diagnosis: Diabetes*	0.2190	0.0488	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.1565	0.0529	0.0031
Diagnosis: Other/Missing*	0.1260	0.0576	0.0286
Diagnosis: Polycystic Kidney Disease*	-0.2124	0.0742	0.0042
Diagnosis: Renovascular & Other Vascular Diseases*	0.3114	0.0727	<0.0001
Diagnosis: Tubular and Interstitial Diseases*	0.1963	0.0736	0.0077
Donor Hispanic/Latino	-0.0104	0.0575	0.8565
Donor age: 0-17 (ref=35-49)	-0.0094	0.0628	0.8814
Donor age: 18-34 (ref=35-49)	-0.1024	0.0461	0.0265
Donor age: 50-64 (ref=35-49)	0.2702	0.0505	<0.0001
Donor age: 65+ (ref=35-49)	0.3480	0.0929	0.0002
Donor female	0.0399	0.0334	0.2326
Donor history of hypertension	0.1302	0.0494	0.0084
Donor race: Asian (ref=White)	0.0678	0.1183	0.5664
Donor race: Black (ref=White)	0.1248	0.0509	0.0142
Donor race: Multi-racial, other, unknown or missing (ref=White)	-0.1176	0.1469	0.4232
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.0583	0.1993	0.7698
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.0661	0.0670	0.3239
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.1500	0.0489	0.0022
Donor: cadaveric COD other (ref=COD Head trauma)	0.1400	0.1186	0.2379
Donor: living (ref=cadaveric - COD Head trauma)	-0.1927	0.0565	0.0006
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.2714	0.0522	<0.0001
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0722	0.0129	<0.0001
HLA mismatch: missing (ref=3.5 mismatch)	-0.3517	0.1856	0.0582
Ischemia time: linear (ref=average time**)	0.0061	0.0027	0.0252
Ischemia time: missing (ref=average time**)	0.0484	0.0356	0.1744
Ischemia time: quadratic (ref=average time**)	0.0002	0.0001	0.1234
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1482	0.0686	0.0307
Peak PRA: 10-79 (ref=<10)	0.1037	0.0404	0.0102
Peak PRA: 80-100 (ref=<10)	0.3552	0.0606	<0.0001
Peak PRA: missing (ref=<10)	-0.1557	0.1783	0.3827
Previous transplant of this organ type	0.1233	0.0682	0.0704
Recipient age: 18-34 (ref=35-49)	0.1215	0.0726	0.0941
Recipient age: 50-64 (ref=35-49)	0.2254	0.0587	0.0001
Recipient age: 65+ (ref=35-49)	0.5686	0.0777	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.2950	0.0599	<0.0001
Recipient female	-0.0159	0.0591	0.7874
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.1486	0.1035	0.1508
Recipient medical condition: in ICU (ref=not hospitalized)	0.9703	0.1809	<0.0001
Recipient race: Asian (ref=White)	-0.6214	0.1830	0.0007
Recipient race: Black (ref=White)	0.2820	0.0656	<0.0001
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.2784	0.2542	0.2733
Year of ESRD treatment: missing (ref=years 3-5)	0.8869	0.3180	0.0053
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.3408	0.0481	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.0583	0.0443	0.1881
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.0907	0.0571	0.1123
donor serum creatinine>1.5 1=yes,0=no	0.1241	0.0545	0.0228
Recipient age by recipient race interaction: 18-34 and Asian (ref=35-49 and White)	-0.0164	0.3063	0.9572
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	-0.0946	0.0959	0.3239
Recipient age by recipient race interaction: 18-34 and multi-racial/other/unknown/missing (ref=35-49 and White)	0.5747	0.3647	0.1150
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	0.3626	0.2267	0.1097
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-0.1899	0.0844	0.0244
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	0.3150	0.3076	0.3057
Recipient age by recipient race interaction: 65+ and Asian (ref=35-49 and White)	0.0639	0.3563	0.8576
Recipient age by recipient race interaction: 65+ and Black (ref=35-49 and White)	-0.1906	0.1293	0.1402
Recipient age by recipient race interaction: 65+ and multi-racial/other/unknown/missing (ref=35-49 and White)	0.6742	0.3801	0.0761
Recipient age by recipient sex interaction: 18-34 and female (ref=35-49 and male)	0.2601	0.0910	0.0043
Recipient age by recipient sex interaction: 50-64 and female (ref=35-49 and male)	0.0306	0.0792	0.6991
Recipient age by recipient sex interaction: 65+ and female (ref=35-49 and male)	-0.1382	0.1155	0.2313


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Graft Survival Model Description
1 Month after Transplant
Organ: Kidney
Pediatric (Age 0-17)

96.7% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Donor age: 0-17 (ref=35-49)	-0.1530	0.6554	0.8154
Donor age: 18-34 (ref=35-49)	-0.7239	0.5615	0.1973
Donor age: 50-64 (ref=35-49)	0.3716	1.0596	0.7258
Donor age: 65+ (ref=35-49)	-12.9725	2749.8845	0.9962
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-12.3666	1384.8780	0.9929
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.1156	0.5631	0.8374
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.7184	0.4296	0.0945
Donor: cadaveric COD other (ref=COD Head trauma)	0.1257	1.0359	0.9034
Donor: living (ref=cadaveric - COD Head trauma)	-0.3087	0.4092	0.4506
Recipient age: 0-1 (ref=2-10)	-0.6022	1.0611	0.5703
Recipient age: 11-17 (ref=2-10)	-0.5908	0.4441	0.1833
Year of ESRD treatment: missing (ref=years 3-5)	-11.9292	1468.8137	0.9935
Year of ESRD treatment: year 1 (ref=years 3-5)	0.4093	0.4368	0.3488
Year of ESRD treatment: year 2 (ref=years 3-5)	0.4649	0.4731	0.3258
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.4914	0.5922	0.4067
Recipient age by donor age interaction: 0-1 and 0-17 (ref=2-10 and 35-49)	-11.8843	973.2312	0.9903
Recipient age by donor age interaction: 0-1 and 18-34 (ref=2-10 and 35-49)	2.3611	1.2320	0.0553
Recipient age by donor age interaction: 0-1 and 50-64 (ref=2-10 and 35-49)	2.3506	1.7659	0.1832
Recipient age by donor age interaction: 11-17 and 0-17 (ref=2-10 and 35-49)	0.9564	0.7386	0.1954
Recipient age by donor age interaction: 11-17 and 18-34 (ref=2-10 and 35-49)	0.6862	0.7305	0.3475
Recipient age by donor age interaction: 11-17 and 50-64 (ref=2-10 and 35-49)	-0.4074	1.3117	0.7561


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Graft Survival Model Description
1 Year after Transplant
Organ: Kidney
Pediatric (Age 0-17)

93.5% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Ischemia time: linear (ref=average time**)	0.0176	0.0194	0.3650
Ischemia time: missing (ref=average time**)	-0.5849	0.2680	0.0291
Ischemia time: quadratic (ref=average time**)	-0.0003	0.0015	0.8400
Recipient race: Asian (ref=White)	-13.0023	472.6435	0.9781
Recipient race: Black (ref=White)	0.4461	0.2362	0.0589
Recipient race: Multi-racial, other, unknown or missing (ref=White)	0.3709	0.5211	0.4766
Year of ESRD treatment: missing (ref=years 3-5)	-12.7600	1382.1603	0.9926
Year of ESRD treatment: year 1 (ref=years 3-5)	0.1444	0.3305	0.6622
Year of ESRD treatment: year 2 (ref=years 3-5)	0.7323	0.3457	0.0341
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.2035	0.4769	0.6695


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Graft Survival Model Description
3 Years after Transplant
Organ: Kidney
Pediatric (Age 0-17)

85.9% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Diabetes*	1.7281	1.0508	0.1001
Diagnosis: Focal Segmental Glomerulosclerosis*	0.3456	0.4554	0.4479
Diagnosis: Hypertensive Nephrosclerosis*	0.3184	1.0443	0.7604
Diagnosis: Other Glomerular Diseases*	0.4231	0.3917	0.2800
Diagnosis: Other/Missing*	-0.6542	0.4419	0.1388
Diagnosis: Polycystic Kidney Disease*	-0.0017	0.6295	0.9979
Diagnosis: Renovascular & Other Vascular Diseases*	1.4523	1.0526	0.1677
Diagnosis: Tubular and Interstitial Diseases*	-0.8460	0.7509	0.2598
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.0256	0.7390	0.9723
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0360	0.2855	0.8996
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.0115	0.2043	0.9551
Donor: cadaveric COD other (ref=COD Head trauma)	-0.3579	0.7265	0.6223
Donor: living (ref=cadaveric - COD Head trauma)	-0.3556	0.2134	0.0956
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.3986	0.3206	0.2138
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0654	0.0596	0.2728
HLA mismatch: missing (ref=3.5 mismatch)	0.2653	0.4705	0.5729
Ischemia time: linear (ref=average time**)	0.0177	0.0125	0.1567
Ischemia time: missing (ref=average time**)	-0.3517	0.1861	0.0588
Ischemia time: quadratic (ref=average time**)	-0.0003	0.0009	0.6991
Pre-transplant blood transfusions given: missing (ref=no)	-0.3213	0.2090	0.1242
Pre-transplant blood transfusions given: yes (ref=no)	-0.1331	0.1613	0.4092
Previous transplant of this organ type	1.2136	0.2605	<0.0001
Recipient age: 0-1 (ref=2-10)	0.1306	0.6754	0.8466
Recipient age: 11-17 (ref=2-10)	0.3412	0.3413	0.3173
Recipient race: Asian (ref=White)	-12.9654	539.3449	0.9808
Recipient race: Black (ref=White)	0.8703	0.3134	0.0055
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-12.7427	724.2813	0.9860
Year of ESRD treatment: missing (ref=years 3-5)	1.2643	0.7530	0.0931
Year of ESRD treatment: year 1 (ref=years 3-5)	0.0289	0.2123	0.8916
Year of ESRD treatment: year 2 (ref=years 3-5)	0.3061	0.2285	0.1805
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.4471	0.2790	0.1090
Recipient age by diagnosis interaction: 0-1 and FSG (ref=2-10 and congenital disease)	-11.7607	1253.4432	0.9925
Recipient age by diagnosis interaction: 0-1 and diagnosis other/missing (ref=2-10 and congenital disease)	0.1398	1.2391	0.9102
Recipient age by diagnosis interaction: 0-1 and hypertensive nephrosclerosis (ref=2-10 and congenital disease)	-13.1361	3234.0405	0.9968
Recipient age by diagnosis interaction: 0-1 and other glomerular diseases (ref=2-10 and congenital disease)	0.2655	1.2252	0.8284
Recipient age by diagnosis interaction: 0-1 and polycystic kidneys (ref=2-10 and congenital disease)	1.5646	1.1314	0.1667
Recipient age by diagnosis interaction: 0-1 and tubular and interstitial diseases (ref=2-10 and congenital disease)	-11.9932	734.8273	0.9870
Recipient age by diagnosis interaction: 11-17 and FSG (ref=2-10 and congenital disease)	0.0826	0.5474	0.8800
Recipient age by diagnosis interaction: 11-17 and diagnosis other/missing (ref=2-10 and congenital disease)	0.8280	0.4969	0.0957
Recipient age by diagnosis interaction: 11-17 and hypertensive nephrosclerosis (ref=2-10 and congenital disease)	-1.0532	1.4633	0.4717
Recipient age by diagnosis interaction: 11-17 and other glomerular diseases (ref=2-10 and congenital disease)	-0.0772	0.4695	0.8694
Recipient age by diagnosis interaction: 11-17 and polycystic kidneys (ref=2-10 and congenital disease)	-1.0610	1.2031	0.3779
Recipient age by diagnosis interaction: 11-17 and renovascular & other vascular diseases (ref=2-10 and congenital disease)	-1.7167	1.4689	0.2425
Recipient age by diagnosis interaction: 11-17 and tubular and interstitial diseases (ref=2-10 and congenital disease)	1.3494	0.8121	0.0966
Recipient age by recipient race interaction: 0-1 and Asian (ref=2-10 and white)	17.1091	539.3462	0.9747
Recipient age by recipient race interaction: 0-1 and Black (ref=2-10 and white)	-0.3024	1.1699	0.7960
Recipient age by recipient race interaction: 0-1 and multi-racial/other/unknown/missing (ref=2-10 and white)	-0.4664	1435.5704	0.9997
Recipient age by recipient race interaction: 11-17 and Asian (ref=2-10 and White)	13.2996	539.3451	0.9803
Recipient age by recipient race interaction: 11-17 and Black (ref=2-10 and White)	-0.3790	0.3589	0.2910
Recipient age by recipient race interaction: 11-17 and multi-racial/other/unknown/missing (ref=2-10 and White)	12.6622	724.2815	0.9861


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Patient Survival Model Description
1 Month after First Transplant
Organ: Kidney
Adult (Age 18+)

99.5% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.4770	0.7305	0.5138
Diagnosis: Diabetes*	0.8517	0.2052	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.8402	0.2155	0.0001
Diagnosis: Other/Missing*	0.6143	0.2592	0.0178
Diagnosis: Polycystic Kidney Disease*	-0.6313	0.3958	0.1108
Diagnosis: Renovascular & Other Vascular Diseases*	0.6707	0.2943	0.0227
Diagnosis: Tubular and Interstitial Diseases*	0.5760	0.3279	0.0790
Donor age: 0-17 (ref=35-49)	-0.4724	0.5020	0.3467
Donor age: 18-34 (ref=35-49)	-0.1103	0.3247	0.7340
Donor age: 50-64 (ref=35-49)	-0.1421	0.3859	0.7127
Donor age: 65+ (ref=35-49)	-11.9535	371.8392	0.9744
Donor history of hypertension	-0.0027	0.2010	0.9893
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.6932	1.0083	0.4917
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.1089	0.2633	0.6793
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	-0.1815	0.1804	0.3144
Donor: cadaveric COD other (ref=COD Head trauma)	-0.9409	0.7184	0.1903
Donor: living (ref=cadaveric - COD Head trauma)	-0.4390	0.1906	0.0212
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1305	0.2636	0.6205
Peak PRA: 10-79 (ref=<10)	0.2567	0.1524	0.0921
Peak PRA: 80-100 (ref=<10)	0.4299	0.2511	0.0869
Peak PRA: missing (ref=<10)	0.1253	0.7219	0.8623
Recipient age: 18-34 (ref=35-49)	-1.5203	0.7364	0.0390
Recipient age: 50-64 (ref=35-49)	0.5548	0.2561	0.0303
Recipient age: 65+ (ref=35-49)	0.8869	0.2993	0.0030
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.5553	0.3849	0.1492
Recipient medical condition: in ICU (ref=not hospitalized)	2.6314	0.4652	<0.0001
Transplant procedure type en-bloc or double	-0.3066	0.4623	0.5073
Year of ESRD treatment: missing (ref=years 3-5)	3.3294	0.3299	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.5962	0.1973	0.0025
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.0461	0.1659	0.7811
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.2209	0.2062	0.2842
donor serum creatinine>1.5 1=yes,0=no	0.0083	0.2215	0.9701
Recipient age by donor age interaction: 18-34 and 0-17 (ref=35-49 and 35-49)	1.7970	1.0375	0.0833
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	0.5208	0.9238	0.5729
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	0.7295	1.0699	0.4954
Recipient age by donor age interaction: 18-34 and 65+ (ref=35-49 and 35-49)	1.3457	1022.5239	0.9989
Recipient age by donor age interaction: 50-64 and 0-17 (ref=35-49 and 35-49)	-0.0612	0.6144	0.9206
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	0.0127	0.3934	0.9743
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	0.2580	0.4354	0.5535
Recipient age by donor age interaction: 50-64 and 65+ (ref=35-49 and 35-49)	11.4223	371.8396	0.9755
Recipient age by donor age interaction: 65+ and 0-17 (ref=35-49 and 35-49)	-12.6546	319.1070	0.9684
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	-0.3092	0.5264	0.5569
Recipient age by donor age interaction: 65+ and 50-64 (ref=35-49 and 35-49)	0.5275	0.4856	0.2773
Recipient age by donor age interaction: 65+ and 65+ (ref=35-49 and 35-49)	12.6150	371.8393	0.9729


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Patient Survival Model Description
1 Year after First Transplant
Organ: Kidney
Adult (Age 18+)

96.7% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.1788	0.3855	0.6429
Diagnosis: Diabetes*	0.5356	0.0889	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.3631	0.0977	0.0002
Diagnosis: Other/Missing*	0.3507	0.1151	0.0023
Diagnosis: Polycystic Kidney Disease*	-0.4306	0.1455	0.0031
Diagnosis: Renovascular & Other Vascular Diseases*	0.2501	0.1383	0.0706
Diagnosis: Tubular and Interstitial Diseases*	0.1388	0.1554	0.3719
Donor age: 0-17 (ref=35-49)	-0.4571	0.1288	0.0004
Donor age: 18-34 (ref=35-49)	-0.2875	0.0850	0.0007
Donor age: 50-64 (ref=35-49)	0.0907	0.0879	0.3017
Donor age: 65+ (ref=35-49)	0.2908	0.1549	0.0604
Donor history of hypertension	0.0722	0.0888	0.4160
Donor race: Asian (ref=White)	0.3168	0.1819	0.0816
Donor race: Black (ref=White)	0.0892	0.0954	0.3497
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.2370	0.2604	0.3629
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.5840	0.4516	0.1959
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0427	0.1239	0.7303
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.0068	0.0849	0.9359
Donor: cadaveric COD other (ref=COD Head trauma)	0.0324	0.2175	0.8817
Donor: living (ref=cadaveric - COD Head trauma)	-0.4020	0.0959	<0.0001
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.0640	0.0962	0.5058
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0545	0.0234	0.0196
HLA mismatch: missing (ref=3.5 mismatch)	-0.0119	0.3686	0.9742
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1212	0.1194	0.3101
Peak PRA: 10-79 (ref=<10)	0.0336	0.0747	0.6528
Peak PRA: 80-100 (ref=<10)	0.0487	0.1312	0.7105
Peak PRA: missing (ref=<10)	0.5137	0.3158	0.1038
Recipient age: 18-34 (ref=35-49)	-0.5406	0.1424	0.0001
Recipient age: 50-64 (ref=35-49)	0.7277	0.0777	<0.0001
Recipient age: 65+ (ref=35-49)	1.0917	0.0915	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.2665	0.0998	0.0076
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4661	0.1887	0.0135
Recipient medical condition: in ICU (ref=not hospitalized)	1.6936	0.3817	<0.0001
Recipient race: Asian (ref=White)	-0.2051	0.1527	0.1793
Recipient race: Black (ref=White)	-0.0843	0.0771	0.2742
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.2851	0.2030	0.1602
Year of ESRD treatment: missing (ref=years 3-5)	2.1318	0.2834	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.6878	0.0911	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.2483	0.0795	0.0018
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.1460	0.0978	0.1353
donor serum creatinine>1.5 1=yes,0=no	0.1013	0.0987	0.3047


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Patient Survival Model Description
3 Years after First Transplant
Organ: Kidney
Adult (Age 18+)

93.4% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.0241	0.2488	0.9227
Diagnosis: Diabetes*	0.6295	0.0660	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.1928	0.0774	0.0128
Diagnosis: Other/Missing*	0.0066	0.1013	0.9479
Diagnosis: Polycystic Kidney Disease*	-0.1962	0.1016	0.0535
Diagnosis: Renovascular & Other Vascular Diseases*	0.5007	0.0987	<0.0001
Diagnosis: Tubular and Interstitial Diseases*	0.1340	0.1121	0.2319
Donor Hispanic/Latino	0.0211	0.0813	0.7950
Donor age: 0-17 (ref=35-49)	-0.0633	0.0922	0.4925
Donor age: 18-34 (ref=35-49)	-0.0598	0.0661	0.3658
Donor age: 50-64 (ref=35-49)	0.2258	0.0711	0.0015
Donor age: 65+ (ref=35-49)	0.2892	0.1220	0.0177
Donor history of hypertension	0.0613	0.0678	0.3658
Donor race: Asian (ref=White)	0.0975	0.1610	0.5450
Donor race: Black (ref=White)	0.1107	0.0754	0.1420
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.2205	0.1792	0.2185
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	0.0407	0.2629	0.8769
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.0391	0.0954	0.6821
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.1934	0.0674	0.0041
Donor: cadaveric COD other (ref=COD Head trauma)	0.0431	0.1802	0.8111
Donor: living (ref=cadaveric - COD Head trauma)	-0.1739	0.0755	0.0213
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1530	0.0938	0.1030
Peak PRA: 10-79 (ref=<10)	-0.0247	0.0590	0.6751
Peak PRA: 80-100 (ref=<10)	0.1992	0.1003	0.0471
Peak PRA: missing (ref=<10)	0.0872	0.2177	0.6888
Recipient age: 18-34 (ref=35-49)	-0.4755	0.1018	<0.0001
Recipient age: 50-64 (ref=35-49)	0.6012	0.0596	<0.0001
Recipient age: 65+ (ref=35-49)	1.1187	0.0725	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.4207	0.1637	0.0102
Recipient race: Asian (ref=White)	-0.4642	0.1342	0.0005
Recipient race: Black (ref=White)	-0.1330	0.0599	0.0265
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.1850	0.1567	0.2377
Year of ESRD treatment: missing (ref=years 3-5)	1.1462	0.3820	0.0027
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.6220	0.0666	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.2258	0.0588	0.0001
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.2155	0.0837	0.0100
donor serum creatinine>1.5 1=yes,0=no	-0.0224	0.0791	0.7767
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1416	0.3165	0.6546
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0926	0.1959	0.6363
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1446	0.2654	0.5858


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

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