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Research Resources: Analytic Conventions - Model Description (Kidney-Pancreas)
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Kidney Graft Survival Model Description

Pancreas Graft Survival Model Description

Patient Survival Model Description


Kidney Graft Survival Model Description
1 Month after Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
96.1%  alive at 1 Month  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
HLA mismatch:  0 mismatch (ref=3.5 mismatch) -1.3629 1.0119 0.1780
HLA mismatch: linear ** (ref=3.5 mismatch) -0.1151 0.1063 0.2789
HLA mismatch: missing (ref=3.5 mismatch) -11.2816 1032.9972 0.9913
Previous kidney transplant -0.1704 0.6810 0.8024
Recipient age: 18-34 (ref=35-49) 0.2893 0.2801 0.3017
Recipient age: 50-64 (ref=35-49) -0.0024 0.3721 0.9949
Recipient age: 65+ (ref=35-49) -10.7705 815.9302 0.9895
Year of ESRD treatment: missing (ref=years 3-5) -11.4539 802.3281 0.9886
Year of ESRD treatment: year 1 (ref=years 3-5) -0.6864 0.3369 0.0416
Year of ESRD treatment: year 2 (ref=years 3-5) -0.1203 0.2992 0.6877
Year of ESRD treatment: years 6+ (ref=years 3-5) 0.5722 0.6028 0.3425
       
** HLA is centered on 3.5.

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Kidney Graft Survival Model Description
1 Year after Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
85.8%  alive at 1 Year  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Donor age: 0-17 (ref=35-49) -0.4372 0.2282 0.0554
Donor age: 18-34 (ref=35-49) -0.4759 0.1820 0.0089
Donor age: 50-64 (ref=35-49) 0.1703 0.4043 0.6736
HLA mismatch:  0 mismatch (ref=3.5 mismatch) 0.0800 0.3510 0.8197
HLA mismatch: linear ** (ref=3.5 mismatch) 0.0151 0.0721 0.8340
HLA mismatch: missing (ref=3.5 mismatch) -10.1937 391.3920 0.9792
Year of ESRD treatment: missing (ref=years 3-5) 1.5415 1.0235 0.1320
Year of ESRD treatment: year 1 (ref=years 3-5) -0.3448 0.1975 0.0808
Year of ESRD treatment: year 2 (ref=years 3-5) -0.3115 0.2052 0.1290
Year of ESRD treatment: years 6+ (ref=years 3-5) 0.4451 0.2812 0.1134
Years since onset of DM: 0-19 (ref=25-29) -0.4586 0.2774 0.0982
Years since onset of DM: 20-24 (ref=25-29) -0.1176 0.2283 0.6067
Years since onset of DM: 30+ (ref=25-29) -0.3003 0.2233 0.1786
Years since onset of DM: missing (ref=25-29) 0.0520 0.2635 0.8436
       
** HLA is centered on 3.5.

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Kidney Graft Survival Model Description
3 Years after Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
76.7%  alive at 3 Years  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Donor age: 0-17 (ref=35-49) -0.3318 0.1636 0.0425
Donor age: 18-34 (ref=35-49) -0.4440 0.1403 0.0016
Donor age: 50-64 (ref=35-49) 0.1128 0.2790 0.6859
Recipient female 0.0753 0.1201 0.5310
Year of ESRD treatment: missing (ref=years 3-5) -11.2913 315.0088 0.9714
Year of ESRD treatment: year 1 (ref=years 3-5) -0.5026 0.1473 0.0006
Year of ESRD treatment: year 2 (ref=years 3-5) -0.3203 0.1603 0.0457
Year of ESRD treatment: years 6+ (ref=years 3-5) 0.2629 0.2355 0.2643
Years since onset of DM: 0-19 (ref=25-29) -0.0354 0.2051 0.8628
Years since onset of DM: 20-24 (ref=25-29) 0.0872 0.1792 0.6267
Years since onset of DM: 30+ (ref=25-29) 0.1548 0.1747 0.3753
Years since onset of DM: missing (ref=25-29) 0.5199 0.2148 0.0155
       
** HLA is centered on 3.5.

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Pancreas Graft Survival Model Description
1 Month after Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
89.8%  alive at 1 Month  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Donor age: 0-17 (ref=35-49) -0.8279 0.2613 0.0015
Donor age: 18-34 (ref=35-49) -0.3208 0.1848 0.0826
Donor age: 50-64 (ref=35-49) 0.4988 0.3194 0.1184
Donor female -0.1074 0.1697 0.5268
Donor race: Asian (ref=White) -1.2071 1.0046 0.2295
Donor race: Black (ref=White) 0.0268 0.2287 0.9067
Donor race: Multi-racial, other, unknown or missing (ref=White) -0.1561 1.0051 0.8766
Donor: cadaveric COD CNS tumor (ref=COD Head trauma) 0.3575 0.7268 0.6228
Donor: cadaveric COD anoxia (ref=COD Head trauma) 0.3633 0.2797 0.1940
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma) 0.2374 0.1968 0.2276
Donor: cadaveric COD other (ref=COD Head trauma) 0.0412 0.5147 0.9361
HLA mismatch:  0 mismatch (ref=3.5 mismatch) 0.2503 0.3063 0.4138
HLA mismatch: linear ** (ref=3.5 mismatch) -0.0047 0.0667 0.9433
HLA mismatch: missing (ref=3.5 mismatch) -11.9599 1000.3453 0.9905
Recipient female 0.0348 0.1489 0.8151
Recipient race: Asian (ref=White) -11.9616 303.3294 0.9685
Recipient race: Black (ref=White) 0.2913 0.2186 0.1827
Recipient race: Multi-racial, other, unknown or missing (ref=White) 0.2342 0.7204 0.7451
       
** HLA is centered on 3.5.

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Pancreas Graft Survival Model Description
1 Year after Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
84.3%  alive at 1 Year  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Donor age: 0-17 (ref=35-49) -0.4205 0.2608 0.1069
Donor age: 18-34 (ref=35-49) -0.3121 0.1919 0.1039
Donor age: 50-64 (ref=35-49) 0.6639 0.3384 0.0498
Donor: cadaveric COD CNS tumor (ref=COD Head trauma) 0.5359 0.5108 0.2941
Donor: cadaveric COD anoxia (ref=COD Head trauma) 0.1955 0.2282 0.3917
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma) 0.1406 0.1490 0.3454
Donor: cadaveric COD other (ref=COD Head trauma) 0.3408 0.3289 0.3000
Duct management: missing (ref=cystostomy) 1.0126 0.6405 0.1139
Duct management: non-cystostomy (ref=cystostomy) -0.0060 0.1406 0.9657
HLA mismatch:  0 mismatch (ref=3.5 mismatch) 0.4358 0.4045 0.2813
HLA mismatch: linear ** (ref=3.5 mismatch) 0.0882 0.0947 0.3522
HLA mismatch: missing (ref=3.5 mismatch) -10.1655 391.8763 0.9793
Recipient female 0.0263 0.1164 0.8215
Donor age by HLA mismatch interaction: 0-17 and 0 mismatch (ref=35-49 and 3.5 mismatch) -0.5400 0.7468 0.4697
Donor age by HLA mismatch interaction: 0-17 and mismatch (ref=35-49 and 3.5 mismatch) -0.0894 0.1659 0.5899
Donor age by HLA mismatch interaction: 0-17 and mismatch missing (ref=35-49 and 3.5 mismatch) -0.1154 554.1970 0.9998
Donor age by HLA mismatch interaction: 18-34 and 0 mismatch (ref=35-49 and 3.5 mismatch) -0.1562 0.5495 0.7762
Donor age by HLA mismatch interaction: 18-34 and mismatch (ref=35-49 and 3.5 mismatch) -0.0536 0.1214 0.6586
Donor age by HLA mismatch interaction: 50-64 and 0 mismatch (ref=35-49 and 3.5 mismatch) -1.0485 1.1799 0.3742
Donor age by HLA mismatch interaction: 50-64 and mismatch (ref=35-49 and 3.5 mismatch) -0.1698 0.2217 0.4436
       
** HLA is centered on 3.5.

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Pancreas Graft Survival Model Description
3 Years after Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
76.2%  alive at 3 Years  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Donor age: 0-17 (ref=35-49) -0.6493 0.2183 0.0029
Donor age: 18-34 (ref=35-49) -0.3827 0.1710 0.0253
Donor age: 50-64 (ref=35-49) 0.5102 0.2508 0.0419
Donor female -0.0478 0.1096 0.6630
Donor: cadaveric COD CNS tumor (ref=COD Head trauma) 0.5702 0.4184 0.1729
Donor: cadaveric COD anoxia (ref=COD Head trauma) 0.0776 0.2001 0.6983
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma) 0.1915 0.1305 0.1424
Donor: cadaveric COD other (ref=COD Head trauma) 0.0003 0.3267 0.9992
HLA mismatch:  0 mismatch (ref=3.5 mismatch) -0.2090 0.5176 0.6863
HLA mismatch: linear ** (ref=3.5 mismatch) 0.1693 0.0813 0.0372
HLA mismatch: missing (ref=3.5 mismatch) -11.8527 498.4222 0.9810
Recipient age: 18-34 (ref=35-49) 0.0690 0.1192 0.5627
Recipient age: 50-64 (ref=35-49) 0.0101 0.1740 0.9538
Recipient age: 65+ (ref=35-49) -11.2281 351.5785 0.9745
Years since onset of DM: 0-19 (ref=25-29) -0.0225 0.1647 0.8915
Years since onset of DM: 20-24 (ref=25-29) -0.0145 0.1487 0.9223
Years since onset of DM: 30+ (ref=25-29) 0.0813 0.1458 0.5773
Years since onset of DM: missing (ref=25-29) 0.3857 0.1815 0.0336
Donor age by HLA mismatch interaction: 0-17 and 0 mismatch (ref=35-49 and 3.5 mismatch) -0.1323 0.8931 0.8823
Donor age by HLA mismatch interaction: 0-17 and mismatch (ref=35-49 and 3.5 mismatch) 0.1040 0.1325 0.4325
Donor age by HLA mismatch interaction: 18-34 and 0 mismatch (ref=35-49 and 3.5 mismatch) 0.4677 0.6162 0.4478
Donor age by HLA mismatch interaction: 18-34 and mismatch (ref=35-49 and 3.5 mismatch) -0.0458 0.1085 0.6729
Donor age by HLA mismatch interaction: 18-34 and mismatch missing (ref=35-49 and 3.5 mismatch) 13.2095 498.4232 0.9789
Donor age by HLA mismatch interaction: 50-64 and 0 mismatch (ref=35-49 and 3.5 mismatch) -0.5529 1.1499 0.6306
Donor age by HLA mismatch interaction: 50-64 and mismatch (ref=35-49 and 3.5 mismatch) -0.2819 0.1680 0.0934
       
** HLA is centered on 3.5.

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Patient Survival Model Description
1 Month after First Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
97.6%  alive at 1 Month  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
HLA mismatch:  0 mismatch (ref=3.5 mismatch) -14.0548 905.9987 0.9876
HLA mismatch: linear ** (ref=3.5 mismatch) -0.0191 0.1672 0.9092
HLA mismatch: missing (ref=3.5 mismatch) -14.5725 7671.7170 0.9985
Recipient age: 18-34 (ref=35-49) -0.1485 0.4753 0.7546
Recipient age: 50-64 (ref=35-49) -0.1072 0.5532 0.8463
Recipient age: 65+ (ref=35-49) -13.9080 5599.1712 0.9980
Year of ESRD treatment: missing (ref=years 3-5) -14.9082 6521.0242 0.9982
Year of ESRD treatment: year 1 (ref=years 3-5) -1.6666 0.6365 0.0088
Year of ESRD treatment: year 2 (ref=years 3-5) -0.6714 0.4633 0.1473
Year of ESRD treatment: years 6+ (ref=years 3-5) 0.4604 0.5702 0.4194
       
** HLA is centered on 3.5.

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Patient Survival Model Description
1 Year after First Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
92.9%  alive at 1 Year  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Recipient age: 18-34 (ref=35-49) -0.2431 0.2466 0.3243
Recipient age: 50-64 (ref=35-49) 0.2306 0.2497 0.3556
Recipient age: 65+ (ref=35-49) -9.9667 361.8651 0.9780
Year of ESRD treatment: missing (ref=years 3-5) 1.8097 1.0130 0.0740
Year of ESRD treatment: year 1 (ref=years 3-5) -0.7692 0.2530 0.0024
Year of ESRD treatment: year 2 (ref=years 3-5) -0.4026 0.2384 0.0912
Year of ESRD treatment: years 6+ (ref=years 3-5) 0.4833 0.3161 0.1263
       
** HLA is centered on 3.5.

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Patient Survival Model Description
3 Years after First Transplant
Organ: Kidney / Pancreas
Adult (Age 18+)
87.9%  alive at 3 Years  when all covariates=0.
Patient Characteristic Covariates beta standard error p-value
Recipient age: 18-34 (ref=35-49) -0.1548 0.1942 0.4255
Recipient age: 50-64 (ref=35-49) 0.1442 0.2374 0.5436
Recipient age: 65+ (ref=35-49) -11.1920 579.4835 0.9846
Recipient female -0.0591 0.1520 0.6972
Year of ESRD treatment: missing (ref=years 3-5) -11.3930 408.3106 0.9777
Year of ESRD treatment: year 1 (ref=years 3-5) -0.8196 0.1846 <0.0001
Year of ESRD treatment: year 2 (ref=years 3-5) -0.3689 0.1907 0.0531
Year of ESRD treatment: years 6+ (ref=years 3-5) 0.3340 0.2716 0.2187
Years since onset of DM: 0-19 (ref=25-29) -0.1308 0.2846 0.6457
Years since onset of DM: 20-24 (ref=25-29) 0.1542 0.2348 0.5114
Years since onset of DM: 30+ (ref=25-29) 0.4122 0.2224 0.0638
Years since onset of DM: missing (ref=25-29) 0.7973 0.2606 0.0022
       
** HLA is centered on 3.5.

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