Analytic Conventions - Model Description (Kidney

Model Descriptions on This Page

Graft Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Patient Survival Model Description

Adult (Age 18+)

Living Donor Graft Survival Model Description
1 Month after Transplant
Organ: Kidney
Adult (Age 18+)

97.2% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.8063	0.3565	0.0237
Diagnosis: Diabetes*	0.2690	0.1741	0.1224
Diagnosis: Hypertensive Nephrosclerosis*	0.1538	0.2149	0.4742
Diagnosis: Other/Missing*	0.2754	0.2082	0.1860
Diagnosis: Polycystic Kidney Disease*	-0.0217	0.2513	0.9310
Diagnosis: Renovascular & Other Vascular Diseases*	-0.6080	0.4271	0.1546
Diagnosis: Tubular and Interstitial Diseases*	0.1496	0.2725	0.5830
Donor Hispanic/Latino	-0.1095	0.3298	0.7399
Donor age: 11-17 (ref==35-49)	-12.5973	1899.2431	0.9947
Donor age: 18-34 (ref=35-49)	0.1249	0.2190	0.5683
Donor age: 50-64 (ref=35-49)	0.2940	0.2677	0.2721
Donor age: 65+ (ref=35-49)	0.2152	1.0099	0.8313
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	0.0062	0.1837	0.9733
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0644	0.0470	0.1701
HLA mismatch: missing (ref=3.5 mismatch)	0.8196	0.2925	0.0051
Ischemia time: linear (ref=average time**)	0.0027	0.0320	0.9329
Ischemia time: missing (ref=average time**)	-0.4193	0.6954	0.5465
Ischemia time: quadratic (ref=average time**)	0.0000	0.0009	0.9714
Peak PRA: 10-79 (ref=<10)	-0.0117	0.2693	0.9653
Peak PRA: 80-100 (ref=<10)	0.6361	0.5173	0.2188
Peak PRA: missing (ref=<10)	-0.0761	0.6002	0.8991
Previous transplant of this organ type	0.2278	0.2915	0.4345
Recipient age: 18-34 (ref=35-49)	-0.0434	0.2433	0.8584
Recipient age: 50-64 (ref=35-49)	-0.1020	0.2237	0.6484
Recipient age: 65+ (ref=35-49)	0.2593	0.2972	0.3829
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.2157	0.4237	0.6106
Recipient female	0.3634	0.1330	0.0063
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.2162	0.3599	0.5480
Recipient medical condition: in ICU (ref=not hospitalized)	1.3684	0.7149	0.0556
Year of ESRD treatment: missing (ref=years 3-5)	1.7592	0.5252	0.0008
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.3911	0.1547	0.0114
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.2380	0.1826	0.1925
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.3764	0.2744	0.1702
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	-0.1086	0.3432	0.7516
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	-0.4695	0.4588	0.3061
Recipient age by donor age interaction: 18-34 and 65+ (ref=35-49 and 35-49)	-12.8409	992.2510	0.9897
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	0.2247	0.3296	0.4954
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	-0.1100	0.3794	0.7719
Recipient age by donor age interaction: 50-64 and 65+ (ref=35-49 and 35-49)	0.0781	1.4353	0.9566
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	-0.0315	0.6080	0.9586
Recipient age by donor age interaction: 65+ and 50-64 (ref=35-49 and 35-49)	-0.6335	0.6890	0.3578
Recipient age by donor age interaction: 65+ and 65+ (ref=35-49 and 35-49)	-0.7762	1.4498	0.5924
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	0.4870	0.4501	0.2793
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.4836	0.5707	0.3968
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.3418	1.0801	0.7517
Recipient sex by peak PRA interaction: female and 10-79 (ref=male and <10)	0.2474	0.3285	0.4513
Recipient sex by peak PRA interaction: female and 80+ (ref=male and <10)	-0.0246	0.5903	0.9667
Recipient sex by peak PRA interaction: female and missing (ref=male and <10)	-12.7535	314.2162	0.9676


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Graft Survival Model Description
1 Year after Transplant
Organ: Kidney
Adult (Age 18+)

88.4% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.2038	0.3137	0.5159
Diagnosis: Diabetes*	0.2180	0.1172	0.0628
Diagnosis: Hypertensive Nephrosclerosis*	0.1295	0.1427	0.3641
Diagnosis: Other/Missing*	0.1948	0.1430	0.1733
Diagnosis: Polycystic Kidney Disease*	-0.3431	0.1874	0.0671
Diagnosis: Renovascular & Other Vascular Diseases*	-0.3198	0.2407	0.1839
Diagnosis: Tubular and Interstitial Diseases*	0.3354	0.1713	0.0502
Donor Hispanic/Latino	-0.0331	0.2169	0.8787
Donor age: 11-17 (ref==35-49)	-8.1707	147.9366	0.9560
Donor age: 18-34 (ref=35-49)	-0.0370	0.0926	0.6894
Donor age: 50-64 (ref=35-49)	0.0259	0.1071	0.8088
Donor age: 65+ (ref=35-49)	-0.1147	0.3640	0.7528
Donor race: Asian (ref=White)	0.3841	0.3927	0.3280
Donor race: Black (ref=White)	0.5305	0.2581	0.0398
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.6692	0.2775	0.0159
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.4078	0.1459	0.0052
HLA mismatch: linear ** (ref=3.5 mismatch)	0.1107	0.0301	0.0002
HLA mismatch: missing (ref=3.5 mismatch)	0.2294	0.2396	0.3384
Ischemia time: linear (ref=average time**)	0.0198	0.0193	0.3034
Ischemia time: missing (ref=average time**)	-0.7695	0.4645	0.0976
Ischemia time: quadratic (ref=average time**)	-0.0006	0.0009	0.5220
Peak PRA: 10-79 (ref=<10)	-0.0632	0.1727	0.7143
Peak PRA: 80-100 (ref=<10)	0.9212	0.3013	0.0022
Peak PRA: missing (ref=<10)	0.2923	0.3698	0.4293
Previous transplant of this organ type	0.1136	0.2026	0.5751
Recipient age: 18-34 (ref=35-49)	0.0505	0.1192	0.6716
Recipient age: 50-64 (ref=35-49)	0.2740	0.1043	0.0086
Recipient age: 65+ (ref=35-49)	0.5704	0.1514	0.0002
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	0.0951	0.2734	0.7278
Recipient female	0.0883	0.0918	0.3359
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4066	0.2229	0.0681
Recipient medical condition: in ICU (ref=not hospitalized)	0.7102	0.7121	0.3186
Recipient race: Asian (ref=White)	-0.6180	0.3930	0.1159
Recipient race: Black (ref=White)	-0.3955	0.2577	0.1248
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.3480	0.2660	0.1909
Year of ESRD treatment: missing (ref=years 3-5)	1.2242	0.4608	0.0079
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.5437	0.1032	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.3556	0.1199	0.0030
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.2231	0.1839	0.2252
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1742	0.3126	0.5773
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1975	0.3047	0.5168
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1395	0.5112	0.7850
Recipient sex by peak PRA interaction: female and 10-79 (ref=male and <10)	0.3434	0.2196	0.1179
Recipient sex by peak PRA interaction: female and 80+ (ref=male and <10)	-0.2128	0.3655	0.5603
Recipient sex by peak PRA interaction: female and missing (ref=male and <10)	-0.5946	0.6204	0.3378


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Graft Survival Model Description
3 Years after Transplant
Organ: Kidney
Adult (Age 18+)

91.3% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.2925	0.2459	0.2343
Diagnosis: Diabetes*	0.2634	0.0968	0.0065
Diagnosis: Hypertensive Nephrosclerosis*	0.1284	0.1210	0.2889
Diagnosis: Other/Missing*	0.2551	0.1131	0.0241
Diagnosis: Polycystic Kidney Disease*	-0.3032	0.1666	0.0689
Diagnosis: Renovascular & Other Vascular Diseases*	0.5008	0.1570	0.0014
Diagnosis: Tubular and Interstitial Diseases*	0.4057	0.1317	0.0021
Donor Hispanic/Latino	-0.2691	0.1814	0.1380
Donor age: 11-17 (ref==35-49)	-9.1508	139.7693	0.9478
Donor age: 18-34 (ref=35-49)	-0.0337	0.0798	0.6724
Donor age: 50-64 (ref=35-49)	0.2274	0.0879	0.0097
Donor age: 65+ (ref=35-49)	0.0797	0.3118	0.7984
Donor female	0.0779	0.0681	0.2528
Donor race: Asian (ref=White)	0.3415	0.3930	0.3849
Donor race: Black (ref=White)	0.3907	0.2179	0.0730
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.0624	0.2154	0.7720
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.4679	0.1210	0.0001
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0537	0.0263	0.0411
HLA mismatch: missing (ref=3.5 mismatch)	-0.3753	0.2304	0.1033
Ischemia time: linear (ref=average time**)	-0.0129	0.0189	0.4938
Ischemia time: missing (ref=average time**)	0.1175	0.4141	0.7766
Ischemia time: quadratic (ref=average time**)	0.0000	0.0006	0.9652
Peak PRA: 10-79 (ref=<10)	0.2196	0.0901	0.0147
Peak PRA: 80-100 (ref=<10)	0.3744	0.1865	0.0447
Peak PRA: missing (ref=<10)	-0.1341	0.1980	0.4983
Previous transplant of this organ type	0.3316	0.1647	0.0441
Recipient age: 18-34 (ref=35-49)	0.1698	0.1287	0.1872
Recipient age: 50-64 (ref=35-49)	0.1764	0.1226	0.1504
Recipient age: 65+ (ref=35-49)	0.5414	0.1814	0.0028
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	0.0561	0.1699	0.7411
Recipient female	-0.0481	0.1250	0.7004
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	-0.0372	0.1965	0.8497
Recipient medical condition: in ICU (ref=not hospitalized)	0.8403	0.4113	0.0411
Recipient race: Asian (ref=White)	-0.9443	0.5854	0.1067
Recipient race: Black (ref=White)	-0.0327	0.2497	0.8957
Recipient race: Multi-racial, other, unknown or missing (ref=White)	0.0054	0.4341	0.9900
Year of ESRD treatment: missing (ref=years 3-5)	2.4032	0.6322	0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.3123	0.0935	0.0008
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.0419	0.1047	0.6889
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.4624	0.1702	0.0066
Recipient age by recipient race interaction: 18-34 and Asian (ref=35-49 and White)	-0.9737	0.8728	0.2646
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	0.0191	0.2069	0.9267
Recipient age by recipient race interaction: 18-34 and multi-racial/other/unknown/missing (ref=35-49 and White)	-0.2377	0.6536	0.7161
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	-0.0541	0.7158	0.9398
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-0.0543	0.2222	0.8071
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	-0.1743	0.5880	0.7669
Recipient age by recipient race interaction: 65+ and Asian (ref=35-49 and White)	0.3108	1.1365	0.7845
Recipient age by recipient race interaction: 65+ and Black (ref=35-49 and White)	-0.8311	0.4660	0.0745
Recipient age by recipient race interaction: 65+ and multi-racial/other/unknown/missing (ref=35-49 and White)	-0.5934	1.0961	0.5883
Recipient age by recipient sex interaction: 18-34 and female (ref=35-49 and male)	0.4186	0.1691	0.0133
Recipient age by recipient sex interaction: 50-64 and female (ref=35-49 and male)	0.1533	0.1747	0.3803
Recipient age by recipient sex interaction: 65+ and female (ref=35-49 and male)	0.3585	0.2889	0.2146


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Graft Survival Model Description
1 Month after Transplant
Organ: Kidney
Pediatric (Age 0-17)

100.0% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Donor age: 11-17 (ref==35-49)	-15.3479	8125.5120	0.9985
Donor age: 18-34 (ref=35-49)	-0.7971	0.7075	0.2599
Donor age: 50-64 (ref=35-49)	-15.5935	3160.2454	0.9961
Recipient age: 0-1 (ref=2-10)	-15.5815	1922.9148	0.9935
Recipient age: 11-17 (ref=2-10)	-0.6702	0.5411	0.2155
Year of ESRD treatment: missing (ref=years 3-5)	-0.4597	9673.1240	1.0000
Year of ESRD treatment: year 1 (ref=years 3-5)	15.3856	1731.0863	0.9929
Year of ESRD treatment: year 2 (ref=years 3-5)	15.3705	1731.0863	0.9929
Year of ESRD treatment: years 6+ (ref=years 3-5)	15.2584	1731.0865	0.9930
Recipient age by donor age interaction: 0-1 and 18-34 (ref=2-10 and 35-49)	17.3908	1922.9150	0.9928
Recipient age by donor age interaction: 0-1 and 50-64 (ref=2-10 and 35-49)	33.0961	3699.2910	0.9929
Recipient age by donor age interaction: 11-17 and 18-34 (ref=2-10 and 35-49)	0.5231	1.0608	0.6219
Recipient age by donor age interaction: 11-17 and 50-64 (ref=2-10 and 35-49)	15.6120	3160.2456	0.9961


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Graft Survival Model Description
1 Year after Transplant
Organ: Kidney
Pediatric (Age 0-17)

100.0% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Ischemia time: linear (ref=average time**)	-32.0229	18.6411	0.0858
Ischemia time: missing (ref=average time**)	244.3848	145.9908	0.0941
Ischemia time: quadratic (ref=average time**)	-1.0422	0.5941	0.0794
Recipient race: Asian (ref=White)	-13.1395	862.6677	0.9878
Recipient race: Black (ref=White)	0.0438	0.4817	0.9275
Recipient race: Multi-racial, other, unknown or missing (ref=White)	1.1481	0.5388	0.0331
Year of ESRD treatment: missing (ref=years 3-5)	-12.6556	1986.5017	0.9949
Year of ESRD treatment: year 1 (ref=years 3-5)	0.3249	0.7332	0.6577
Year of ESRD treatment: year 2 (ref=years 3-5)	0.7142	0.7834	0.3619
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.9139	0.9175	0.3192


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Graft Survival Model Description
3 Years after Transplant
Organ: Kidney
Pediatric (Age 0-17)

96.4% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Diabetes*	-14.4053	5066.0508	0.9977
Diagnosis: Focal Segmental Glomerulosclerosis*	0.4097	1.1670	0.7255
Diagnosis: Hypertensive Nephrosclerosis*	1.4784	1.1934	0.2154
Diagnosis: Other Glomerular Diseases*	1.2195	0.7719	0.1141
Diagnosis: Other/Missing*	-0.0697	0.9227	0.9398
Diagnosis: Polycystic Kidney Disease*	0.8970	0.9195	0.3293
Diagnosis: Renovascular & Other Vascular Diseases*	-13.3674	4220.7171	0.9975
Diagnosis: Tubular and Interstitial Diseases*	0.4770	0.9204	0.6043
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.2056	0.5325	0.6995
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0187	0.1099	0.8646
HLA mismatch: missing (ref=3.5 mismatch)	0.0429	0.5626	0.9392
Ischemia time: linear (ref=average time**)	-0.0011	0.1137	0.9925
Ischemia time: missing (ref=average time**)	-0.3586	2.4574	0.8840
Ischemia time: quadratic (ref=average time**)	-0.0024	0.0049	0.6240
Pre-transplant blood transfusions given: missing (ref=no)	0.0813	0.3216	0.8003
Pre-transplant blood transfusions given: yes (ref=no)	0.1863	0.2695	0.4892
Previous transplant of this organ type	0.6516	0.5672	0.2506
Recipient age: 0-1 (ref=2-10)	-0.5928	1.4250	0.6774
Recipient age: 11-17 (ref=2-10)	1.1304	0.6725	0.0928
Recipient race: Asian (ref=White)	-13.9247	2688.4526	0.9959
Recipient race: Black (ref=White)	0.5434	0.6594	0.4098
Recipient race: Multi-racial, other, unknown or missing (ref=White)	0.3939	0.7357	0.5924
Year of ESRD treatment: missing (ref=years 3-5)	0.9688	1.1651	0.4057
Year of ESRD treatment: year 1 (ref=years 3-5)	0.3672	0.5051	0.4672
Year of ESRD treatment: year 2 (ref=years 3-5)	0.1448	0.5715	0.8000
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.0196	0.7093	0.9780
Recipient age by diagnosis interaction: 0-1 and FSG (ref=2-10 and congenital disease)	-13.2145	4116.3975	0.9974
Recipient age by diagnosis interaction: 0-1 and diagnosis other/missing (ref=2-10 and congenital disease)	0.9345	1.7084	0.5844
Recipient age by diagnosis interaction: 0-1 and hypertensive nephrosclerosis (ref=2-10 and congenital disease)	-14.2402	7250.0365	0.9984
Recipient age by diagnosis interaction: 0-1 and other glomerular diseases (ref=2-10 and congenital disease)	1.3288	1.8092	0.4627
Recipient age by diagnosis interaction: 0-1 and polycystic kidneys (ref=2-10 and congenital disease)	2.0852	1.7495	0.2333
Recipient age by diagnosis interaction: 0-1 and tubular and interstitial diseases (ref=2-10 and congenital disease)	-13.6907	1197.5691	0.9909
Recipient age by diagnosis interaction: 11-17 and FSG (ref=2-10 and congenital disease)	-0.9802	1.3410	0.4648
Recipient age by diagnosis interaction: 11-17 and diagnosis other/missing (ref=2-10 and congenital disease)	0.3227	1.0018	0.7474
Recipient age by diagnosis interaction: 11-17 and hypertensive nephrosclerosis (ref=2-10 and congenital disease)	-15.9920	1471.4977	0.9913
Recipient age by diagnosis interaction: 11-17 and other glomerular diseases (ref=2-10 and congenital disease)	-0.9494	0.8655	0.2726
Recipient age by diagnosis interaction: 11-17 and polycystic kidneys (ref=2-10 and congenital disease)	-0.2305	1.4096	0.8701
Recipient age by diagnosis interaction: 11-17 and renovascular & other vascular diseases (ref=2-10 and congenital disease)	-1.2588	4517.4766	0.9998
Recipient age by diagnosis interaction: 11-17 and tubular and interstitial diseases (ref=2-10 and congenital disease)	-0.0559	1.0180	0.9562
Recipient age by recipient race interaction: 0-1 and Asian (ref=2-10 and white)	19.7623	2688.4531	0.9941
Recipient age by recipient race interaction: 0-1 and Black (ref=2-10 and white)	1.9823	1.5782	0.2091
Recipient age by recipient race interaction: 0-1 and multi-racial/other/unknown/missing (ref=2-10 and white)	-15.9898	3516.8588	0.9964
Recipient age by recipient race interaction: 11-17 and Asian (ref=2-10 and White)	14.9489	2688.4528	0.9956
Recipient age by recipient race interaction: 11-17 and Black (ref=2-10 and White)	0.4654	0.7226	0.5195


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Patient Survival Model Description
1 Month after First Transplant
Organ: Kidney
Adult (Age 18+)

99.7% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	1.8833	0.8072	0.0196
Diagnosis: Diabetes*	1.3972	0.4295	0.0011
Diagnosis: Hypertensive Nephrosclerosis*	1.2691	0.4693	0.0068
Diagnosis: Other/Missing*	0.4836	0.5886	0.4113
Diagnosis: Polycystic Kidney Disease*	0.3845	0.6341	0.5443
Diagnosis: Renovascular & Other Vascular Diseases*	0.6254	0.6937	0.3673
Diagnosis: Tubular and Interstitial Diseases*	0.2386	0.8040	0.7666
Donor age: 11-17 (ref==35-49)	-1.2433	15416.2922	0.9999
Donor age: 18-34 (ref=35-49)	-0.3667	0.5795	0.5268
Donor age: 50-64 (ref=35-49)	-14.1197	753.4887	0.9850
Donor age: 65+ (ref=35-49)	-14.0271	2848.0310	0.9961
Peak PRA: 10-79 (ref=<10)	0.3100	0.3369	0.3575
Peak PRA: 80-100 (ref=<10)	0.4514	0.7257	0.5339
Peak PRA: missing (ref=<10)	0.4827	0.7472	0.5183
Recipient age: 18-34 (ref=35-49)	-14.1894	579.4723	0.9805
Recipient age: 50-64 (ref=35-49)	0.1555	0.4309	0.7182
Recipient age: 65+ (ref=35-49)	0.3921	0.5374	0.4656
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	1.2316	0.5182	0.0175
Recipient medical condition: in ICU (ref=not hospitalized)	-13.7801	3758.2925	0.9971
Year of ESRD treatment: missing (ref=years 3-5)	3.0628	0.6445	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.9266	0.3053	0.0024
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.5423	0.3411	0.1119
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.4326	0.6261	0.4895
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	14.2144	579.4727	0.9804
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	27.5409	950.5442	0.9769
Recipient age by donor age interaction: 18-34 and 65+ (ref=35-49 and 35-49)	13.9819	8131.3228	0.9986
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	0.6320	0.7211	0.3808
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	14.7547	753.4889	0.9844
Recipient age by donor age interaction: 50-64 and 65+ (ref=35-49 and 35-49)	-0.3698	4125.3281	0.9999
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	0.2350	1.2410	0.8498
Recipient age by donor age interaction: 65+ and 50-64 (ref=35-49 and 35-49)	15.3492	753.4890	0.9837
Recipient age by donor age interaction: 65+ and 65+ (ref=35-49 and 35-49)	15.5503	2848.0312	0.9956


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Patient Survival Model Description
1 Year after First Transplant
Organ: Kidney
Adult (Age 18+)

97.7% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.4351	0.5215	0.4041
Diagnosis: Diabetes*	0.6928	0.1759	0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.4249	0.2124	0.0454
Diagnosis: Other/Missing*	0.4979	0.2209	0.0242
Diagnosis: Polycystic Kidney Disease*	-0.6014	0.3249	0.0642
Diagnosis: Renovascular & Other Vascular Diseases*	0.2713	0.2992	0.3645
Diagnosis: Tubular and Interstitial Diseases*	0.3465	0.2882	0.2292
Donor age: 11-17 (ref==35-49)	-9.5817	977.5986	0.9922
Donor age: 18-34 (ref=35-49)	-0.0423	0.1445	0.7697
Donor age: 50-64 (ref=35-49)	0.0369	0.1614	0.8194
Donor age: 65+ (ref=35-49)	0.0737	0.4633	0.8736
Donor race: Asian (ref=White)	1.1634	0.5175	0.0246
Donor race: Black (ref=White)	0.2096	0.3728	0.5740
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.9309	0.4112	0.0236
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.4826	0.2534	0.0568
HLA mismatch: linear ** (ref=3.5 mismatch)	0.1391	0.0462	0.0026
HLA mismatch: missing (ref=3.5 mismatch)	0.0795	0.3776	0.8333
Peak PRA: 10-79 (ref=<10)	0.1485	0.1705	0.3840
Peak PRA: 80-100 (ref=<10)	0.4612	0.3646	0.2059
Peak PRA: missing (ref=<10)	0.5484	0.3818	0.1509
Recipient age: 18-34 (ref=35-49)	-0.4993	0.2359	0.0343
Recipient age: 50-64 (ref=35-49)	0.7320	0.1540	<0.0001
Recipient age: 65+ (ref=35-49)	1.1230	0.1969	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.1191	0.1909	0.5328
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.7098	0.3090	0.0216
Recipient medical condition: in ICU (ref=not hospitalized)	-10.3687	280.2961	0.9705
Recipient race: Asian (ref=White)	-1.1894	0.5694	0.0367
Recipient race: Black (ref=White)	-0.3327	0.3655	0.3627
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-1.0827	0.4632	0.0194
Year of ESRD treatment: missing (ref=years 3-5)	1.5100	0.6013	0.0120
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.9137	0.1482	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.5378	0.1643	0.0011
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.3678	0.3012	0.2222


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Living Donor Patient Survival Model Description
3 Years after First Transplant
Organ: Kidney
Adult (Age 18+)

94.1% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.5726	0.3958	0.1479
Diagnosis: Diabetes*	0.7532	0.1369	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	-0.0487	0.1952	0.8029
Diagnosis: Other/Missing*	0.2907	0.1917	0.1293
Diagnosis: Polycystic Kidney Disease*	-0.1032	0.2250	0.6464
Diagnosis: Renovascular & Other Vascular Diseases*	0.6346	0.2227	0.0044
Diagnosis: Tubular and Interstitial Diseases*	0.4716	0.2084	0.0236
Donor Hispanic/Latino	-0.1348	0.2789	0.6289
Donor age: 11-17 (ref==35-49)	-9.6737	256.4892	0.9699
Donor age: 18-34 (ref=35-49)	-0.0114	0.1171	0.9228
Donor age: 50-64 (ref=35-49)	0.0645	0.1297	0.6190
Donor age: 65+ (ref=35-49)	0.0621	0.3921	0.8741
Donor race: Asian (ref=White)	0.7939	0.4875	0.1034
Donor race: Black (ref=White)	0.1050	0.3287	0.7494
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.4971	0.2799	0.0758
Peak PRA: 10-79 (ref=<10)	-0.1336	0.1527	0.3815
Peak PRA: 80-100 (ref=<10)	0.1069	0.3624	0.7680
Peak PRA: missing (ref=<10)	-0.0713	0.2566	0.7810
Recipient age: 18-34 (ref=35-49)	-0.3898	0.1700	0.0219
Recipient age: 50-64 (ref=35-49)	0.5878	0.1246	<0.0001
Recipient age: 65+ (ref=35-49)	1.1673	0.1699	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.6223	0.4195	0.1380
Recipient race: Asian (ref=White)	-1.2974	0.5507	0.0185
Recipient race: Black (ref=White)	-0.0605	0.3205	0.8503
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.6691	0.4129	0.1051
Year of ESRD treatment: missing (ref=years 3-5)	1.8529	0.7270	0.0108
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.7317	0.1248	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.4572	0.1419	0.0013
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.1614	0.2971	0.5869
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0540	0.5941	0.9275
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	0.1596	0.4602	0.7287
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	0.1563	0.6404	0.8072


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.