ustransplant.org - Research Resources - Analytic Conventions - Model Description (Kidney

Research Resources: Analytic Conventions - Model Description (Kidney - Deceased)

Model Descriptions on This Page

Graft Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Patient Survival Model Description

Adult (Age 18+)

Deceased Donor Graft Survival Model Description
1 Month after Transplant
Organ: Kidney
Adult (Age 18+)

97.5% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.1897	0.4184	0.6503
Diagnosis: Diabetes*	-0.0680	0.1201	0.5713
Diagnosis: Hypertensive Nephrosclerosis*	0.0930	0.1176	0.4291
Diagnosis: Other/Missing*	0.2850	0.1361	0.0363
Diagnosis: Polycystic Kidney Disease*	-0.2723	0.1698	0.1088
Diagnosis: Renovascular & Other Vascular Diseases*	-0.1182	0.1829	0.5181
Diagnosis: Tubular and Interstitial Diseases*	0.2886	0.1787	0.1062
Donor Hispanic/Latino	0.2842	0.1038	0.0062
Donor age: 0-17 (ref=35-49)	-0.1266	0.2165	0.5587
Donor age: 18-34 (ref=35-49)	-0.0383	0.1784	0.8300
Donor age: 50-64 (ref=35-49)	0.1399	0.1828	0.4440
Donor age: 65+ (ref=35-49)	0.4231	0.3848	0.2716
Donor history of hypertension	0.2289	0.0974	0.0188
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.0944	0.4141	0.8196
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0002	0.1303	0.9988
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.1788	0.0934	0.0554
Donor: cadaveric COD other (ref=COD Head trauma)	-0.3150	0.2755	0.2529
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.3520	0.1158	0.0024
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0838	0.0286	0.0035
HLA mismatch: missing (ref=3.5 mismatch)	0.6583	0.7114	0.3548
Ischemia time: linear (ref=average time**)	0.0180	0.0075	0.0166
Ischemia time: missing (ref=average time**)	-0.1720	0.0769	0.0253
Ischemia time: quadratic (ref=average time**)	-0.0005	0.0005	0.3080
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1862	0.1493	0.2122
Peak PRA: 10-79 (ref=<10)	0.1387	0.1219	0.2549
Peak PRA: 80-100 (ref=<10)	0.7014	0.1575	<0.0001
Peak PRA: missing (ref=<10)	0.2149	1.0050	0.8307
Previous transplant of this organ type	0.1497	0.1532	0.3285
Recipient age: 18-34 (ref=35-49)	0.1979	0.2010	0.3249
Recipient age: 50-64 (ref=35-49)	0.2686	0.1590	0.0911
Recipient age: 65+ (ref=35-49)	0.4912	0.2164	0.0232
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.0671	0.1946	0.7301
Recipient female	0.2129	0.0942	0.0238
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.6230	0.2135	0.0035
Recipient medical condition: in ICU (ref=not hospitalized)	2.0865	0.3457	<0.0001
Transplant procedure type en-bloc or double	0.4110	0.1634	0.0119
Year of ESRD treatment: missing (ref=years 3-5)	1.8467	0.3158	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.3454	0.1287	0.0073
Year of ESRD treatment: year 2 (ref=years 3-5)	0.0716	0.1026	0.4851
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.0306	0.1052	0.7710
donor serum creatinine>1.5 1=yes,0=no	0.2147	0.1030	0.0371
Recipient age by donor age interaction: 18-34 and 0-17 (ref=35-49 and 35-49)	0.1801	0.3197	0.5732
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	-0.1857	0.2863	0.5166
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	-0.2126	0.3082	0.4902
Recipient age by donor age interaction: 18-34 and 65+ (ref=35-49 and 35-49)	0.8418	0.5656	0.1367
Recipient age by donor age interaction: 50-64 and 0-17 (ref=35-49 and 35-49)	0.0100	0.2884	0.9724
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	-0.1578	0.2392	0.5094
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	-0.1005	0.2196	0.6471
Recipient age by donor age interaction: 50-64 and 65+ (ref=35-49 and 35-49)	-0.3928	0.4332	0.3645
Recipient age by donor age interaction: 65+ and 0-17 (ref=35-49 and 35-49)	-0.9491	0.5709	0.0964
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	-0.1541	0.3380	0.6485
Recipient age by donor age interaction: 65+ and 50-64 (ref=35-49 and 35-49)	-0.1955	0.2933	0.5052
Recipient age by donor age interaction: 65+ and 65+ (ref=35-49 and 35-49)	-0.3651	0.4585	0.4259
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0181	0.3061	0.9528
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.4283	0.2872	0.1360
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1251	0.3981	0.7533
Recipient sex by peak PRA interaction: female and 10-79 (ref=male and <10)	-0.0264	0.1707	0.8771
Recipient sex by peak PRA interaction: female and 80+ (ref=male and <10)	-0.4425	0.2049	0.0308
Recipient sex by peak PRA interaction: female and missing (ref=male and <10)	1.1886	1.2340	0.3355


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Graft Survival Model Description
1 Year after Transplant
Organ: Kidney
Adult (Age 18+)

92.6% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.3863	0.3076	0.2093
Diagnosis: Diabetes*	0.1667	0.0748	0.0259
Diagnosis: Hypertensive Nephrosclerosis*	0.1904	0.0767	0.0131
Diagnosis: Other/Missing*	0.1984	0.0916	0.0303
Diagnosis: Polycystic Kidney Disease*	-0.3086	0.1120	0.0059
Diagnosis: Renovascular & Other Vascular Diseases*	0.0914	0.1112	0.4111
Diagnosis: Tubular and Interstitial Diseases*	0.1012	0.1277	0.4279
Donor Hispanic/Latino	0.0951	0.0736	0.1963
Donor age: 0-17 (ref=35-49)	-0.1753	0.0841	0.0371
Donor age: 18-34 (ref=35-49)	-0.3189	0.0717	<0.0001
Donor age: 50-64 (ref=35-49)	0.1482	0.0743	0.0461
Donor age: 65+ (ref=35-49)	0.4453	0.1262	0.0004
Donor history of hypertension	0.1489	0.0617	0.0159
Donor race: Asian (ref=White)	0.1058	0.1527	0.4882
Donor race: Black (ref=White)	0.1913	0.0704	0.0066
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.4685	0.2203	0.0334
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.1470	0.2621	0.5749
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0446	0.0859	0.6033
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.1727	0.0595	0.0037
Donor: cadaveric COD other (ref=COD Head trauma)	0.0078	0.1506	0.9588
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.2378	0.0729	0.0011
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0569	0.0185	0.0021
HLA mismatch: missing (ref=3.5 mismatch)	0.5644	0.5022	0.2611
Ischemia time: linear (ref=average time**)	0.0122	0.0046	0.0077
Ischemia time: missing (ref=average time**)	-0.0484	0.0478	0.3112
Ischemia time: quadratic (ref=average time**)	0.0001	0.0002	0.7981
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1169	0.0912	0.1997
Peak PRA: 10-79 (ref=<10)	0.0586	0.0747	0.4327
Peak PRA: 80-100 (ref=<10)	0.4657	0.1054	<0.0001
Peak PRA: missing (ref=<10)	-0.8924	1.0017	0.3730
Previous transplant of this organ type	0.1970	0.1031	0.0560
Recipient age: 18-34 (ref=35-49)	0.0491	0.0802	0.5402
Recipient age: 50-64 (ref=35-49)	0.2555	0.0588	<0.0001
Recipient age: 65+ (ref=35-49)	0.5162	0.0764	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.2736	0.1439	0.0573
Recipient female	-0.0249	0.0610	0.6838
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.4559	0.1503	0.0024
Recipient medical condition: in ICU (ref=not hospitalized)	1.5247	0.3203	<0.0001
Recipient race: Asian (ref=White)	-0.2206	0.1201	0.0662
Recipient race: Black (ref=White)	0.0599	0.0557	0.2824
Recipient race: Multi-racial, other, unknown or missing (ref=White)	0.0221	0.1624	0.8919
Year of ESRD treatment: missing (ref=years 3-5)	1.5370	0.2643	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.2608	0.0784	0.0009
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.0703	0.0669	0.2935
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.0594	0.0682	0.3842
donor serum creatinine>1.5 1=yes,0=no	0.1022	0.0686	0.1364
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1131	0.2399	0.6372
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	0.0508	0.1831	0.7814
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0378	0.2553	0.8823
Recipient sex by peak PRA interaction: female and 10-79 (ref=male and <10)	0.0481	0.1101	0.6619
Recipient sex by peak PRA interaction: female and 80+ (ref=male and <10)	-0.2781	0.1400	0.0471
Recipient sex by peak PRA interaction: female and missing (ref=male and <10)	2.0190	1.1580	0.0812


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Graft Survival Model Description
3 Years after Transplant
Organ: Kidney
Adult (Age 18+)

86.8% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	0.0947	0.1553	0.5420
Diagnosis: Diabetes*	0.1929	0.0567	0.0007
Diagnosis: Hypertensive Nephrosclerosis*	0.1457	0.0593	0.0141
Diagnosis: Other/Missing*	0.0743	0.0669	0.2666
Diagnosis: Polycystic Kidney Disease*	-0.2013	0.0832	0.0155
Diagnosis: Renovascular & Other Vascular Diseases*	0.2549	0.0822	0.0019
Diagnosis: Tubular and Interstitial Diseases*	0.1086	0.0892	0.2233
Donor Hispanic/Latino	-0.0150	0.0632	0.8125
Donor age: 0-17 (ref=35-49)	-0.0225	0.0657	0.7320
Donor age: 18-34 (ref=35-49)	-0.1510	0.0570	0.0081
Donor age: 50-64 (ref=35-49)	0.3005	0.0629	<0.0001
Donor age: 65+ (ref=35-49)	0.4002	0.1047	0.0001
Donor female	0.0342	0.0385	0.3742
Donor history of hypertension	0.1249	0.0498	0.0121
Donor race: Asian (ref=White)	0.1279	0.1268	0.3133
Donor race: Black (ref=White)	0.1143	0.0579	0.0485
Donor race: Multi-racial, other, unknown or missing (ref=White)	-0.2707	0.2309	0.2411
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.0644	0.1996	0.7468
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.0532	0.0674	0.4303
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.1282	0.0504	0.0109
Donor: cadaveric COD other (ref=COD Head trauma)	0.1184	0.1190	0.3196
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.2157	0.0584	0.0002
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0830	0.0149	<0.0001
HLA mismatch: missing (ref=3.5 mismatch)	-0.2379	0.3180	0.4544
Ischemia time: linear (ref=average time**)	0.0130	0.0037	0.0004
Ischemia time: missing (ref=average time**)	0.0888	0.0385	0.0211
Ischemia time: quadratic (ref=average time**)	0.0000	0.0001	0.9392
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.1019	0.0753	0.1757
Peak PRA: 10-79 (ref=<10)	0.0761	0.0452	0.0922
Peak PRA: 80-100 (ref=<10)	0.3401	0.0648	<0.0001
Peak PRA: missing (ref=<10)	-0.1383	0.4489	0.7580
Previous transplant of this organ type	0.1071	0.0753	0.1551
Recipient age: 18-34 (ref=35-49)	0.0730	0.0902	0.4187
Recipient age: 50-64 (ref=35-49)	0.2360	0.0674	0.0005
Recipient age: 65+ (ref=35-49)	0.5661	0.0870	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.3573	0.0682	<0.0001
Recipient female	-0.0021	0.0672	0.9752
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.2047	0.1235	0.0974
Recipient medical condition: in ICU (ref=not hospitalized)	1.0413	0.2020	<0.0001
Recipient race: Asian (ref=White)	-0.6256	0.1956	0.0014
Recipient race: Black (ref=White)	0.2733	0.0715	0.0001
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.4704	0.3199	0.1414
Year of ESRD treatment: missing (ref=years 3-5)	0.6188	0.3808	0.1042
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.3519	0.0601	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.0606	0.0496	0.2216
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.0385	0.0604	0.5241
donor serum creatinine>1.5 1=yes,0=no	0.1275	0.0548	0.0200
Recipient age by recipient race interaction: 18-34 and Asian (ref=35-49 and White)	0.3152	0.3292	0.3384
Recipient age by recipient race interaction: 18-34 and Black (ref=35-49 and White)	-0.0669	0.1139	0.5572
Recipient age by recipient race interaction: 18-34 and multi-racial/other/unknown/missing (ref=35-49 and White)	0.9927	0.4441	0.0254
Recipient age by recipient race interaction: 50-64 and Asian (ref=35-49 and White)	0.3996	0.2411	0.0974
Recipient age by recipient race interaction: 50-64 and Black (ref=35-49 and White)	-0.2096	0.0927	0.0237
Recipient age by recipient race interaction: 50-64 and multi-racial/other/unknown/missing (ref=35-49 and White)	0.5413	0.3734	0.1471
Recipient age by recipient race interaction: 65+ and Asian (ref=35-49 and White)	0.0514	0.3766	0.8915
Recipient age by recipient race interaction: 65+ and Black (ref=35-49 and White)	-0.1377	0.1372	0.3156
Recipient age by recipient race interaction: 65+ and multi-racial/other/unknown/missing (ref=35-49 and White)	0.9937	0.4360	0.0227
Recipient age by recipient sex interaction: 18-34 and female (ref=35-49 and male)	0.1499	0.1109	0.1765
Recipient age by recipient sex interaction: 50-64 and female (ref=35-49 and male)	-0.0062	0.0891	0.9448
Recipient age by recipient sex interaction: 65+ and female (ref=35-49 and male)	-0.2190	0.1268	0.0842


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Graft Survival Model Description
1 Month after Transplant
Organ: Kidney
Pediatric (Age 0-17)

97.0% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Donor age: 0-17 (ref=35-49)	0.0852	0.7966	0.9148
Donor age: 18-34 (ref=35-49)	-0.5355	0.9282	0.5640
Donor age: 50-64 (ref=35-49)	2.5338	1.1903	0.0333
Donor age: 65+ (ref=35-49)	-13.0039	3225.2752	0.9968
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-12.6818	1589.1166	0.9936
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.1647	0.5674	0.7716
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.7790	0.4467	0.0812
Donor: cadaveric COD other (ref=COD Head trauma)	0.1830	1.0410	0.8604
Recipient age: 0-1 (ref=2-10)	0.9621	1.1809	0.4152
Recipient age: 11-17 (ref=2-10)	-0.4812	0.7730	0.5337
Year of ESRD treatment: missing (ref=years 3-5)	-12.5675	3278.4264	0.9969
Year of ESRD treatment: year 1 (ref=years 3-5)	0.1842	0.4808	0.7017
Year of ESRD treatment: year 2 (ref=years 3-5)	0.2812	0.5179	0.5872
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.3642	0.6382	0.5682
Recipient age by donor age interaction: 0-1 and 0-17 (ref=2-10 and 35-49)	-13.8485	1224.1996	0.9910
Recipient age by donor age interaction: 0-1 and 18-34 (ref=2-10 and 35-49)	-13.2508	1366.8982	0.9923
Recipient age by donor age interaction: 11-17 and 0-17 (ref=2-10 and 35-49)	0.8739	0.9689	0.3671
Recipient age by donor age interaction: 11-17 and 18-34 (ref=2-10 and 35-49)	0.7134	1.1239	0.5256
Recipient age by donor age interaction: 11-17 and 50-64 (ref=2-10 and 35-49)	-2.5616	1.6363	0.1175


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Graft Survival Model Description
1 Year after Transplant
Organ: Kidney
Pediatric (Age 0-17)

93.4% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Ischemia time: linear (ref=average time**)	0.0250	0.0273	0.3610
Ischemia time: missing (ref=average time**)	-0.3670	0.3023	0.2247
Ischemia time: quadratic (ref=average time**)	-0.0005	0.0021	0.7995
Recipient race: Asian (ref=White)	-14.0614	913.8396	0.9877
Recipient race: Black (ref=White)	0.4873	0.2826	0.0846
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-13.9198	847.1482	0.9869
Year of ESRD treatment: missing (ref=years 3-5)	-13.9947	4063.1488	0.9973
Year of ESRD treatment: year 1 (ref=years 3-5)	0.2595	0.3913	0.5072
Year of ESRD treatment: year 2 (ref=years 3-5)	0.8271	0.3892	0.0336
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.0773	0.5937	0.8964


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Graft Survival Model Description
3 Years after Transplant
Organ: Kidney
Pediatric (Age 0-17)

81.4% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Diabetes*	2.8494	1.1112	0.0103
Diagnosis: Focal Segmental Glomerulosclerosis*	0.1289	0.4953	0.7946
Diagnosis: Hypertensive Nephrosclerosis*	-14.2183	2417.7018	0.9953
Diagnosis: Other Glomerular Diseases*	0.0445	0.4724	0.9250
Diagnosis: Other/Missing*	-1.0162	0.5182	0.0499
Diagnosis: Polycystic Kidney Disease*	-0.5616	1.0411	0.5896
Diagnosis: Renovascular & Other Vascular Diseases*	1.4021	1.0922	0.1993
Diagnosis: Tubular and Interstitial Diseases*	-14.2992	763.3158	0.9851
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	0.0312	0.7428	0.9665
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0380	0.2910	0.8960
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.0268	0.2104	0.8987
Donor: cadaveric COD other (ref=COD Head trauma)	-0.3765	0.7338	0.6079
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	-0.5749	0.4096	0.1605
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0856	0.0733	0.2431
HLA mismatch: missing (ref=3.5 mismatch)	1.4589	1.0474	0.1637
Ischemia time: linear (ref=average time**)	0.0088	0.0159	0.5812
Ischemia time: missing (ref=average time**)	-0.2329	0.2046	0.2551
Ischemia time: quadratic (ref=average time**)	0.0026	0.0016	0.1076
Pre-transplant blood transfusions given: missing (ref=no)	-0.6479	0.2820	0.0216
Pre-transplant blood transfusions given: yes (ref=no)	-0.3913	0.2056	0.0571
Previous transplant of this organ type	1.5437	0.3141	<0.0001
Recipient age: 0-1 (ref=2-10)	1.0804	0.7824	0.1673
Recipient age: 11-17 (ref=2-10)	-0.0222	0.4244	0.9583
Recipient race: Asian (ref=White)	-13.5898	887.4509	0.9878
Recipient race: Black (ref=White)	0.9173	0.3695	0.0130
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-13.8197	1309.3987	0.9916
Year of ESRD treatment: missing (ref=years 3-5)	3.5513	1.1239	0.0016
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.2352	0.2668	0.3780
Year of ESRD treatment: year 2 (ref=years 3-5)	0.5400	0.2658	0.0422
Year of ESRD treatment: years 6+ (ref=years 3-5)	-0.4183	0.3067	0.1727
Recipient age by diagnosis interaction: 0-1 and diagnosis other/missing (ref=2-10 and congenital disease)	-14.1051	1499.2994	0.9925
Recipient age by diagnosis interaction: 0-1 and other glomerular diseases (ref=2-10 and congenital disease)	-13.5274	3361.9055	0.9968
Recipient age by diagnosis interaction: 11-17 and FSG (ref=2-10 and congenital disease)	0.6313	0.6216	0.3098
Recipient age by diagnosis interaction: 11-17 and diagnosis other/missing (ref=2-10 and congenital disease)	1.1371	0.5899	0.0539
Recipient age by diagnosis interaction: 11-17 and hypertensive nephrosclerosis (ref=2-10 and congenital disease)	14.3531	2417.7021	0.9953
Recipient age by diagnosis interaction: 11-17 and other glomerular diseases (ref=2-10 and congenital disease)	0.2854	0.5951	0.6316
Recipient age by diagnosis interaction: 11-17 and polycystic kidneys (ref=2-10 and congenital disease)	-14.0935	1053.0112	0.9893
Recipient age by diagnosis interaction: 11-17 and renovascular & other vascular diseases (ref=2-10 and congenital disease)	-1.2152	1.5147	0.4224
Recipient age by diagnosis interaction: 11-17 and tubular and interstitial diseases (ref=2-10 and congenital disease)	14.6376	763.3160	0.9847
Recipient age by recipient race interaction: 0-1 and Black (ref=2-10 and white)	-14.7669	1607.9096	0.9927
Recipient age by recipient race interaction: 0-1 and multi-racial/other/unknown/missing (ref=2-10 and white)	-2.7272	3120.4368	0.9993
Recipient age by recipient race interaction: 11-17 and Asian (ref=2-10 and White)	13.9131	887.4511	0.9875
Recipient age by recipient race interaction: 11-17 and Black (ref=2-10 and White)	-0.7648	0.4433	0.0845
Recipient age by recipient race interaction: 11-17 and multi-racial/other/unknown/missing (ref=2-10 and White)	13.4836	1309.3989	0.9918


* Reference for diagnosis group is congenital, familial, and metabolic kidney diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Patient Survival Model Description
1 Month after First Transplant
Organ: Kidney
Adult (Age 18+)

99.5% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-13.2573	823.6292	0.9872
Diagnosis: Diabetes*	0.6966	0.2376	0.0034
Diagnosis: Hypertensive Nephrosclerosis*	0.7312	0.2446	0.0028
Diagnosis: Other/Missing*	0.7085	0.2917	0.0151
Diagnosis: Polycystic Kidney Disease*	-1.1323	0.5399	0.0360
Diagnosis: Renovascular & Other Vascular Diseases*	0.6800	0.3273	0.0377
Diagnosis: Tubular and Interstitial Diseases*	0.7222	0.3630	0.0467
Donor age: 0-17 (ref=35-49)	-0.3583	0.5342	0.5023
Donor age: 18-34 (ref=35-49)	0.0168	0.4076	0.9670
Donor age: 50-64 (ref=35-49)	0.0827	0.4443	0.8523
Donor age: 65+ (ref=35-49)	-13.9722	1047.6795	0.9894
Donor history of hypertension	-0.0236	0.2012	0.9064
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.7421	1.0089	0.4620
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.1307	0.2640	0.6206
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	-0.2349	0.1839	0.2015
Donor: cadaveric COD other (ref=COD Head trauma)	-0.9552	0.7191	0.1841
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.2884	0.2943	0.3271
Peak PRA: 10-79 (ref=<10)	0.2622	0.1715	0.1262
Peak PRA: 80-100 (ref=<10)	0.4146	0.2679	0.1217
Peak PRA: missing (ref=<10)	-13.4681	1198.5547	0.9910
Recipient age: 18-34 (ref=35-49)	-0.7983	0.7611	0.2942
Recipient age: 50-64 (ref=35-49)	0.7662	0.3334	0.0216
Recipient age: 65+ (ref=35-49)	1.1021	0.3809	0.0038
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.0266	0.5843	0.9637
Recipient medical condition: in ICU (ref=not hospitalized)	2.8570	0.4883	<0.0001
Transplant procedure type en-bloc or double	-0.3047	0.4630	0.5105
Year of ESRD treatment: missing (ref=years 3-5)	3.3376	0.4015	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.4682	0.2636	0.0756
Year of ESRD treatment: year 2 (ref=years 3-5)	0.1040	0.1870	0.5781
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.2035	0.2192	0.3531
donor serum creatinine>1.5 1=yes,0=no	0.0024	0.2221	0.9916
Recipient age by donor age interaction: 18-34 and 0-17 (ref=35-49 and 35-49)	1.0064	1.0544	0.3399
Recipient age by donor age interaction: 18-34 and 18-34 (ref=35-49 and 35-49)	-13.1686	428.8452	0.9755
Recipient age by donor age interaction: 18-34 and 50-64 (ref=35-49 and 35-49)	-0.3796	1.2964	0.7697
Recipient age by donor age interaction: 18-34 and 65+ (ref=35-49 and 35-49)	0.5678	2795.2551	0.9998
Recipient age by donor age interaction: 50-64 and 0-17 (ref=35-49 and 35-49)	-0.3145	0.6498	0.6284
Recipient age by donor age interaction: 50-64 and 18-34 (ref=35-49 and 35-49)	-0.2895	0.4841	0.5498
Recipient age by donor age interaction: 50-64 and 50-64 (ref=35-49 and 35-49)	-0.2299	0.4945	0.6420
Recipient age by donor age interaction: 50-64 and 65+ (ref=35-49 and 35-49)	13.2618	1047.6797	0.9899
Recipient age by donor age interaction: 65+ and 0-17 (ref=35-49 and 35-49)	-14.7263	787.4766	0.9851
Recipient age by donor age interaction: 65+ and 18-34 (ref=35-49 and 35-49)	-0.5657	0.6088	0.3528
Recipient age by donor age interaction: 65+ and 50-64 (ref=35-49 and 35-49)	0.0022	0.5493	0.9969
Recipient age by donor age interaction: 65+ and 65+ (ref=35-49 and 35-49)	14.3199	1047.6796	0.9891


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Patient Survival Model Description
1 Year after First Transplant
Organ: Kidney
Adult (Age 18+)

96.5% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.6560	0.5845	0.2617
Diagnosis: Diabetes*	0.4857	0.1033	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.3347	0.1108	0.0025
Diagnosis: Other/Missing*	0.3043	0.1351	0.0243
Diagnosis: Polycystic Kidney Disease*	-0.3980	0.1633	0.0148
Diagnosis: Renovascular & Other Vascular Diseases*	0.2296	0.1564	0.1420
Diagnosis: Tubular and Interstitial Diseases*	0.0944	0.1850	0.6100
Donor age: 0-17 (ref=35-49)	-0.5162	0.1323	0.0001
Donor age: 18-34 (ref=35-49)	-0.4268	0.1050	<0.0001
Donor age: 50-64 (ref=35-49)	0.1173	0.1069	0.2727
Donor age: 65+ (ref=35-49)	0.3519	0.1763	0.0460
Donor history of hypertension	0.0649	0.0890	0.4660
Donor race: Asian (ref=White)	0.2742	0.2090	0.1894
Donor race: Black (ref=White)	0.1077	0.1082	0.3195
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.0189	0.3805	0.9604
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	-0.6058	0.4519	0.1801
Donor: cadaveric COD anoxia (ref=COD Head trauma)	-0.0700	0.1243	0.5731
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	-0.0459	0.0862	0.5949
Donor: cadaveric COD other (ref=COD Head trauma)	-0.0101	0.2181	0.9630
HLA mismatch: 0 mismatch (ref=3.5 mismatch)	0.0100	0.1052	0.9239
HLA mismatch: linear ** (ref=3.5 mismatch)	0.0362	0.0272	0.1835
HLA mismatch: missing (ref=3.5 mismatch)	-9.5204	141.1091	0.9462
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.0741	0.1300	0.5684
Peak PRA: 10-79 (ref=<10)	0.0161	0.0831	0.8467
Peak PRA: 80-100 (ref=<10)	0.0038	0.1405	0.9781
Peak PRA: missing (ref=<10)	0.5100	0.5827	0.3814
Recipient age: 18-34 (ref=35-49)	-0.5712	0.1809	0.0016
Recipient age: 50-64 (ref=35-49)	0.7259	0.0906	<0.0001
Recipient age: 65+ (ref=35-49)	1.0993	0.1047	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.3138	0.1175	0.0076
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.3454	0.2392	0.1488
Recipient medical condition: in ICU (ref=not hospitalized)	2.0429	0.3844	<0.0001
Recipient race: Asian (ref=White)	-0.1197	0.1617	0.4589
Recipient race: Black (ref=White)	-0.0451	0.0831	0.5873
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.1165	0.2303	0.6130
Year of ESRD treatment: missing (ref=years 3-5)	2.2818	0.3232	<0.0001
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.5627	0.1164	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.1836	0.0906	0.0428
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.1443	0.1036	0.1639
donor serum creatinine>1.5 1=yes,0=no	0.1065	0.0992	0.2827


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

Deceased Donor Patient Survival Model Description
3 Years after First Transplant
Organ: Kidney
Adult (Age 18+)

93.4% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Congenital, Rare Familial, & Metabolic Disorders*	-0.2966	0.3225	0.3578
Diagnosis: Diabetes*	0.5835	0.0755	<0.0001
Diagnosis: Hypertensive Nephrosclerosis*	0.2198	0.0853	0.0100
Diagnosis: Other/Missing*	-0.0955	0.1200	0.4259
Diagnosis: Polycystic Kidney Disease*	-0.2252	0.1140	0.0482
Diagnosis: Renovascular & Other Vascular Diseases*	0.4643	0.1104	<0.0001
Diagnosis: Tubular and Interstitial Diseases*	0.0120	0.1336	0.9282
Donor Hispanic/Latino	0.0501	0.0868	0.5641
Donor age: 0-17 (ref=35-49)	-0.0527	0.0961	0.5837
Donor age: 18-34 (ref=35-49)	-0.0786	0.0807	0.3303
Donor age: 50-64 (ref=35-49)	0.3155	0.0867	0.0003
Donor age: 65+ (ref=35-49)	0.3998	0.1374	0.0036
Donor history of hypertension	0.0692	0.0683	0.3108
Donor race: Asian (ref=White)	0.0639	0.1770	0.7179
Donor race: Black (ref=White)	0.1004	0.0850	0.2377
Donor race: Multi-racial, other, unknown or missing (ref=White)	0.1458	0.2605	0.5758
Donor: cadaveric COD CNS tumor (ref=COD Head trauma)	0.0253	0.2634	0.9236
Donor: cadaveric COD anoxia (ref=COD Head trauma)	0.0265	0.0956	0.7820
Donor: cadaveric COD cerebrovascular/stroke (ref=COD Head trauma)	0.1727	0.0688	0.0121
Donor: cadaveric COD other (ref=COD Head trauma)	0.0134	0.1806	0.9408
Meet expanded donor criteria for cadaveric kidney 1=yes,0=no	0.0737	0.1018	0.4691
Peak PRA: 10-79 (ref=<10)	0.0013	0.0642	0.9842
Peak PRA: 80-100 (ref=<10)	0.2111	0.1047	0.0438
Peak PRA: missing (ref=<10)	0.5722	0.4116	0.1645
Recipient age: 18-34 (ref=35-49)	-0.5451	0.1302	<0.0001
Recipient age: 50-64 (ref=35-49)	0.6123	0.0684	<0.0001
Recipient age: 65+ (ref=35-49)	1.1179	0.0810	<0.0001
Recipient ethnicity: Hispanic/Latino (ref=Non-Hispanic/Non-Latino)	-0.3470	0.1809	0.0551
Recipient race: Asian (ref=White)	-0.4191	0.1395	0.0027
Recipient race: Black (ref=White)	-0.1449	0.0636	0.0227
Recipient race: Multi-racial, other, unknown or missing (ref=White)	-0.0974	0.1695	0.5655
Year of ESRD treatment: missing (ref=years 3-5)	0.9560	0.4514	0.0342
Year of ESRD treatment: year 1 (ref=years 3-5)	-0.6152	0.0828	<0.0001
Year of ESRD treatment: year 2 (ref=years 3-5)	-0.1685	0.0647	0.0092
Year of ESRD treatment: years 6+ (ref=years 3-5)	0.2178	0.0875	0.0129
donor serum creatinine>1.5 1=yes,0=no	-0.0122	0.0793	0.8774
Recipient age by recipient ethnicity interaction: 18-34 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.0758	0.3813	0.8424
Recipient age by recipient ethnicity interaction: 50-64 and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.1665	0.2168	0.4424
Recipient age by recipient ethnicity interaction: 65+ and Hispanic/Latino (ref=35-49 and Non-Hispanic/Non-Latino)	-0.2399	0.2923	0.4118


* Reference for diagnosis group is glomerular diseases.
** HLA is centered on 3.5; ischemia time is centered on 17.82 hours.

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