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Research Resources: Analytic Conventions - Model Description (Heart)

Model Descriptions on This Page

Graft Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Patient Survival Model Description

Adult (Age 18+)

Pediatric (Age 0-17)

Graft Survival Model Description
1 Month after Transplant
Organ: Heart
Adult (Age 18+)

95.3% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Cardiomyopathy	-0.1685	0.1414	0.2334
Diagnosis: Congenital Heart Disease	1.0783	0.2734	0.0001
Diagnosis: Other/Missing	0.4156	0.2906	0.1527
Donor age: 0-17	-0.1702	0.2111	0.4203
Donor age: 18-34	-0.3930	0.1485	0.0081
Donor: cadaveric COD cerebrovascular/stroke	0.2663	0.1424	0.0614
Ischemia time: linear (ref=average time*)	0.2796	0.0558	<0.0001
Ischemia time: missing (ref=average time*)	0.2473	0.1862	0.1843
Previous transplant of this organ type	-0.1322	0.4350	0.7612
Recipient age: 50-64 (ref=35-49)	0.3582	0.1356	0.0083
Recipient creatinine: >1.5	0.5980	0.1310	<0.0001
Recipient diabetes: yes (ref=no diabetes/unknown diabetes)	-0.2348	0.1654	0.1556
Recipient height (cm) (ref=avg height*)	-0.0122	0.0048	0.0111
Recipient on ECMO	1.2966	0.5527	0.0190
Recipient on IABP	0.3874	0.2124	0.0682
Recipient on Ventilator	1.0261	0.2250	<0.0001
Recipient race: Asian	-0.7901	0.5888	0.1797
Recipient race: Black	-0.3788	0.2124	0.0745
Recipient race: Multi-racial, other, unknown or missing	0.0327	0.5057	0.9485
Recipient status 1A at transplant	0.3287	0.1337	0.0139



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Graft Survival Model Description
1 Year after Transplant
Organ: Heart
Adult (Age 18+)

90.4% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Cardiomyopathy	-0.1267	0.0973	0.1930
Diagnosis: Congenital Heart Disease	0.7716	0.2214	0.0005
Diagnosis: Other/Missing	0.3056	0.2131	0.1516
Donor age: 0-17	-0.1169	0.1531	0.4452
Donor age: 18-34	-0.2457	0.1078	0.0227
Donor age: 50-64	0.1759	0.1339	0.1890
Donor age: 65+	0.1581	0.7132	0.8245
Donor: cadaveric COD cerebrovascular/stroke	0.2212	0.1023	0.0306
Ischemia time: linear (ref=average time*)	0.1916	0.0408	<0.0001
Ischemia time: missing (ref=average time*)	0.2045	0.1305	0.1172
Previous transplant of this organ type	-0.2398	0.3295	0.4668
Recipient age: 50-64 (ref=35-49)	0.1044	0.1065	0.3271
Recipient age: 65+ (ref=35-49)	0.2356	0.1484	0.1123
Recipient creatinine: >1.5	0.5628	0.0920	<0.0001
Recipient height (cm) (ref=avg height*)	-0.0114	0.0036	0.0013
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.2844	0.1181	0.0160
Recipient medical condition: in ICU (ref=not hospitalized)	0.4561	0.1031	<0.0001
Recipient on ECMO	1.5450	0.4365	0.0004
Recipient on Ventilator	1.0286	0.1624	<0.0001



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Graft Survival Model Description
3 Years after Transplant
Organ: Heart
Adult (Age 18+)

79.8% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Cardiomyopathy	-0.1509	0.0770	0.0501
Diagnosis: Congenital Heart Disease	0.2833	0.2431	0.2439
Donor age: 0-17	-0.3749	0.1099	0.0006
Donor age: 18-34	-0.2641	0.0737	0.0003
Donor age: 65+	1.1004	0.4529	0.0151
Ischemia time: linear (ref=average time*)	0.0933	0.0328	0.0044
Ischemia time: missing (ref=average time*)	0.3299	0.0970	0.0007
Previous transplant of this organ type	0.3384	0.1708	0.0476
Recipient age: 18-34 (ref=35-49)	0.2666	0.1214	0.0280
Recipient age: 65+ (ref=35-49)	0.2277	0.1072	0.0338
Recipient creatinine: <1 and <=1.5	0.1308	0.0826	0.1134
Recipient creatinine: >1.5	0.2354	0.0934	0.0118
Recipient diabetes: yes (ref=no diabetes/unknown diabetes)	0.1414	0.0871	0.1047
Recipient female	0.1806	0.0983	0.0662
Recipient height (cm) (ref=avg height*)	-0.0065	0.0044	0.1388
Recipient on IABP	0.4593	0.1324	0.0005
Recipient on Ventilator	0.8351	0.1395	<0.0001
Recipient race: Asian	0.2835	0.2729	0.2989
Recipient race: Black	0.1821	0.0996	0.0673
Recipient race: Multi-racial, other, unknown or missing	-0.5361	0.4500	0.2334
Recipient status 1A at transplant	-0.0443	0.0984	0.6522
Recipient weight (kg) (ref=avg weight*)	0.0044	0.0025	0.0766



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Graft Survival Model Description
1 Month after Transplant
Organ: Heart
Pediatric (Age 0-17)

95.3% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Recipient cardiac index (=cardiac output/BSA in sq. m) (ref=avg cardiac index*)	-0.7262	0.4918	0.1398
Recipient on Ventilator	1.3655	0.3384	0.0001
Recipient race: Black	-0.5337	0.5321	0.3159



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Graft Survival Model Description
1 Year after Transplant
Organ: Heart
Pediatric (Age 0-17)

91.1% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Recipient cardiac index (=cardiac output/BSA in sq. m) (ref=avg cardiac index*)	-0.7277	0.3321	0.0284
Recipient female	0.3481	0.2444	0.1543
Recipient on Ventilator	1.1851	0.2559	<0.0001
Recipient race: Black	0.1159	0.3029	0.7020
Recipient weight (kg) (ref=avg weight*)	0.0023	0.0052	0.6552



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Graft Survival Model Description
3 Years after Transplant
Organ: Heart
Pediatric (Age 0-17)

80.4% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Donor age: 18-34	-0.4215	0.3308	0.2027
Donor age: 50-64	2.7750	0.8599	0.0012
Donor female	0.2948	0.1850	0.1110
Donor: cadaveric COD anoxia	-0.1864	0.2208	0.3986
Recipient height (cm) (ref=avg height*)	0.0041	0.0036	0.2505
Recipient on ECMO	0.0952	0.4273	0.8238
Recipient on IABP	1.3696	0.5889	0.0200
Recipient race: Black	0.2689	0.2182	0.2177
Recipient weight (kg) (ref=avg weight*)	-0.0069	0.0063	0.2747



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Patient Survival Model Description
1 Month after First Transplant
Organ: Heart
Adult (Age 18+)

95.7% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Cardiomyopathy	-0.2195	0.1407	0.1187
Diagnosis: Congenital Heart Disease	1.1095	0.2717	<0.0001
Diagnosis: Other/Missing	0.4633	0.2831	0.1018
Donor age: 0-34	-0.2938	0.1422	0.0388
Donor: cadaveric COD cerebrovascular/stroke	0.2482	0.1453	0.0877
Ischemia time: linear (ref=average time*)	0.2688	0.0570	<0.0001
Ischemia time: missing (ref=average time*)	0.2532	0.1846	0.1702
Recipient age: 50-64 (ref=35-49)	0.3179	0.1384	0.0216
Recipient creatinine: >1.5	0.6430	0.1325	<0.0001
Recipient height (cm) (ref=avg height*)	-0.0133	0.0049	0.0073
Recipient on ECMO	1.0526	0.6240	0.0916
Recipient on IABP	0.3710	0.2175	0.0880
Recipient on Ventilator	0.9684	0.2378	<0.0001
Recipient race: Asian, multi-racial, other, unknown or missing	-0.2201	0.3634	0.5448
Recipient status 1A at transplant	0.3444	0.1358	0.0112



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Patient Survival Model Description
1 Year after First Transplant
Organ: Heart
Adult (Age 18+)

89.3% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Cardiomyopathy	-0.1842	0.0923	0.0459
Diagnosis: Congenital Heart Disease	0.6570	0.2068	0.0015
Diagnosis: Other/Missing	0.3243	0.2059	0.1153
Donor age: 0-34	-0.2435	0.0983	0.0132
Donor: cadaveric COD cerebrovascular/stroke	0.2564	0.1015	0.0115
Ischemia time: linear (ref=average time*)	0.1875	0.0408	<0.0001
Ischemia time: missing (ref=average time*)	0.2900	0.1254	0.0208
Recipient creatinine: >1.5	0.5896	0.0925	<0.0001
Recipient height (cm) (ref=avg height*)	-0.0116	0.0036	0.0014
Recipient medical condition: hospitalized not in ICU (ref=not hospitalized)	0.2948	0.1181	0.0125
Recipient medical condition: in ICU (ref=not hospitalized)	0.4378	0.1038	<0.0001
Recipient on ECMO	1.5332	0.4737	0.0012
Recipient on Ventilator	1.0060	0.1681	<0.0001



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Patient Survival Model Description
3 Years after First Transplant
Organ: Heart
Adult (Age 18+)

80.6% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Diagnosis: Cardiomyopathy	-0.1555	0.0774	0.0445
Diagnosis: Congenital Heart Disease	0.2435	0.2448	0.3199
Donor age: 0-17	-0.3075	0.1115	0.0058
Donor age: 18-34	-0.2265	0.0752	0.0026
Donor age: 65+	1.1621	0.4530	0.0103
Ischemia time: linear (ref=average time*)	0.0790	0.0335	0.0185
Ischemia time: missing (ref=average time*)	0.3034	0.0998	0.0024
Recipient age: 18-34 (ref=35-49)	0.3536	0.1252	0.0047
Recipient age: 65+ (ref=35-49)	0.2210	0.1093	0.0432
Recipient creatinine: <1 and <=1.5	0.1484	0.0835	0.0756
Recipient creatinine: >1.5	0.2133	0.0966	0.0273
Recipient diabetes: yes (ref=no diabetes/unknown diabetes)	0.1682	0.0875	0.0546
Recipient female	0.1699	0.1003	0.0902
Recipient height (cm) (ref=avg height*)	-0.0072	0.0045	0.1119
Recipient on IABP	0.4171	0.1381	0.0025
Recipient on Ventilator	0.7507	0.1502	<0.0001
Recipient race: Asian	0.3665	0.2734	0.1799
Recipient race: Black	0.2376	0.1000	0.0175
Recipient race: Multi-racial, other, unknown or missing	-0.6039	0.4501	0.1797
Recipient status 1A at transplant	-0.0461	0.1004	0.6458
Recipient weight (kg) (ref=avg weight*)	0.0046	0.0025	0.0694



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Patient Survival Model Description
1 Month after First Transplant
Organ: Heart
Pediatric (Age 0-17)

95.1% alive at 1 Month when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Recipient height (cm) (ref=avg height*)	0.0078	0.0057	0.1721
Recipient on Ventilator	1.3899	0.3743	0.0002
Recipient weight (kg) (ref=avg weight*)	-0.0031	0.0104	0.7661



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Patient Survival Model Description
1 Year after First Transplant
Organ: Heart
Pediatric (Age 0-17)

89.8% alive at 1 Year when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Donor: cadaveric COD cerebrovascular/stroke	-0.2783	0.4667	0.5510
Recipient female	0.4171	0.2578	0.1057



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

Patient Survival Model Description
3 Years after First Transplant
Organ: Heart
Pediatric (Age 0-17)

71.7% alive at 3 Years when all covariates=0.
Patient Characteristic Covariates	beta	standard error	p-value

Donor age: 0-34	-0.4689	0.4383	0.2847
Donor: cadaveric COD anoxia	-0.2454	0.2404	0.3074
Ischemia time: linear (ref=average time*)	0.1123	0.0809	0.1655
Recipient creatinine: >1.5	0.4534	0.4494	0.3130
Recipient height (cm) (ref=avg height*)	-0.0011	0.0023	0.6200
Recipient on ECMO	0.3000	0.4032	0.4569
Recipient on IABP	1.0080	0.7468	0.1771
Recipient race: Black	0.1980	0.2398	0.4091



* Ischemia time is centered on 3.13 hours; recipient weight is centered on 72.60 kg; recipient height is centered on 166.00 cm; cardiac index is centered on 2.23 L/min/sq m .

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