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Transplant Statistics: Annual Report
| Table 14.10 |
| De Novo Posttransplant Solid Malignancy, 1994 to 2000 |
| Heart Recipients |
| Year of Transplant | ||||||||||
| 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | |
| Total # of Post-Tx Malignancies | 123 | 161 | 143 | 141 | 154 | 122 | 86 | 70 | 27 | 9 |
| Malignancies by Type | 78 | 110 | 80 | 93 | 93 | 82 | 56 | 47 | 17 | 6 |
| Squamous/Basal Cell Carcinoma | ||||||||||
| Melanoma | 2 | - | 3 | 2 | 4 | 2 | 4 | 4 | 1 | - |
| Kaposi Sarcoma | - | - | - | - | - | 1 | - | 2 | - | - |
| Central Nervous System | 2 | - | - | 1 | 2 | - | - | - | - | - |
| Genito-Urinary (1) | 4 | 5 | 10 | 5 | 5 | 5 | 4 | 3 | 3 | - |
| Gastro-Intestinal (2) | 22 | 16 | 19 | 16 | 15 | 16 | 9 | 7 | 1 | 2 |
| Primary Hepatic Tumor | - | - | 2 | - | 1 | - | - | - | 1 | - |
| Metastatic Hepatic Tumor | 1 | 2 | 3 | 3 | - | 1 | 2 | - | 1 | - |
| Larynx/Bronchi/Lung | 9 | 13 | 13 | 5 | 16 | 6 | 6 | 3 | 3 | - |
| Breast/Thyroid/Adrenal | 1 | 1 | 2 | - | 5 | 3 | 4 | 1 | - | - |
| Leukemia | 1 | 1 | 2 | 2 | - | - | - | 1 | - | - |
| Sarcoma (3) | - | 4 | - | 2 | 4 | 1 | - | - | - | - |
| Other | 3 | 9 | 8 | 12 | 8 | 4 | 1 | 1 | - | 1 |
| Unknown | - | - | 1 | - | 1 | 1 | - | 1 | - | - |
| Malignancies by Type(%) | 63.4% | 68.3% | 55.9% | 66.0% | 60.4% | 67.2% | 65.1% | 67.1% | 63.0% | 66.7% |
| Squamous/Basal Cell Carcinoma | ||||||||||
| Melanoma | 1.6% | - | 2.1% | 1.4% | 2.6% | 1.6% | 4.7% | 5.7% | 3.7% | - |
| Kaposi Sarcoma | - | - | - | - | - | 0.8% | - | 2.9% | - | - |
| Central Nervous System | 1.6% | - | - | 0.7% | 1.3% | - | - | - | - | - |
| Genito-Urinary (1) | 3.3% | 3.1% | 7.0% | 3.5% | 3.2% | 4.1% | 4.7% | 4.3% | 11.1% | - |
| Gastro-Intestinal (2) | 17.9% | 9.9% | 13.3% | 11.3% | 9.7% | 13.1% | 10.5% | 10.0% | 3.7% | 22.2% |
| Primary Hepatic Tumor | - | - | 1.4% | - | 0.6% | - | - | - | 3.7% | - |
| Metastatic Hepatic Tumor | 0.8% | 1.2% | 2.1% | 2.1% | - | 0.8% | 2.3% | - | 3.7% | - |
| Larynx/Bronchi/Lung | 7.3% | 8.1% | 9.1% | 3.5% | 10.4% | 4.9% | 7.0% | 4.3% | 11.1% | - |
| Breast/Thyroid/Adrenal | 0.8% | 0.6% | 1.4% | - | 3.2% | 2.5% | 4.7% | 1.4% | - | - |
| Leukemia | 0.8% | 0.6% | 1.4% | 1.4% | - | - | - | 1.4% | - | - |
| Sarcoma (3) | - | 2.5% | - | 1.4% | 2.6% | 0.8% | - | - | - | - |
| Other | 2.4% | 5.6% | 5.6% | 8.5% | 5.2% | 3.3% | 1.2% | 1.4% | - | 11.1% |
| Unknown | - | - | 0.7% | - | 0.6% | 0.8% | - | 1.4% | - | - |
| Total # of Patients | 84 | 117 | 113 | 110 | 112 | 93 | 73 | 57 | 21 | 8 |
| Source: OPTN/SRTR Data as of August 1, 2001. |
| (-) = None in category. |
| (1) Genito-Urinary: kidney, bladder, uterine cervix, uterine body, ovarian, vulva, testicular, prostate. |
| (2) Gastro-Intestinal: tongue, throat, esophagus, stomach, small intestine, colo-rectal, liver and biliary tract, pancreas. |
| (3) Sarcoma: fibrosarcoma, osteosarcoma, etc. |
| Patients may have more than one posttransplant malignancy reported due to multiple follow-up forms. |
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