ustransplant Home | Contact us | Site Map
About the SRTRExpand About the SRTR
|
National Transplant StatisticsExpand National Transplant Statistics
|
Program and OPO DataExpand Program and OPO Data
|
Research ResourcesExpand Research Resources
Publication Details

CITATION:
Wolfe RA, McCullough KP, Schaubel DE, Kalbfleisch JD, Murray S, Stegall MD, Leichtman AB. 2007 SRTR Report on the State of Transplantation: Calculating Life Years From Transplant (LYFT): Methods for Kidney and Kidney-Pancreas Candidates. Am J Transplant 2008; 8 (Part 2): 997-1011

Click for the slide presentation Download slide presentation
Download PDF document
Click for the article in PubMed Go to PubMed links
ABSTRACT:
The Organ Procurement and Transplantation Network (OPTN) Kidney Committee is considering a proposal for a new deceased donor kidney allocation system. Among the components under consideration is a strategy to rank candidates in part by the estimated incremental years of life that are expected to be achieved with a transplant from a specific available deceased donor, computed as the difference in expected median lifespan with that transplant compared with remaining on dialysis. This concept has been termed life years from transplant or LYFT. Median lifespans could be calculated, based on objective medical criteria, for each candidate when a deceased donor kidney becomes available, based on Cox regression models using current candidate and donor medical information. The distribution of the calculated LYFT scores for an average nonexpanded criteria donor kidney is similar across candidate sex, race/ethnicity, insurance status and, with the exception of diabetes, diagnosis. LYFT scores tend to be higher for younger candidates and lower for diabetics receiving a kidney-alone rather than a simultaneous kidney-pancreas transplant. Prioritizing candidates with higher LYFT scores for each available kidney could substantially increase total years of life among both transplant candidates and recipients. LYFT is also a powerful metric for assessing trends in allocation outcomes and for comparing alternative allocation systems.

Information for Patients and Families Information for Transplant Community and Policy Makers Information for Researchers
Choose an audience
Transplant Program and OPO Specific Data
Fast Facts give an overview of recent waiting list and transplant activity


Contact the SRTR

315 W. Huron St.
Suite 360
Ann Arbor, MI 48103 USA
Tel: +1 (800) 830-9664
Fax: +1 (734) 665-2103
Email Us

The SRTR is administered by the Arbor Research Collaborative for Health with the University of Michigan,
with oversight and funding from the Health Resources and Services Administration.

About the SRTR | National Transplant Statistics | Program and OPO Data | Research Resources | Privacy Statement