Center and OPO Specific Reports, January 2005

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A Guide to Reading and Understanding the Center-Specific Reports (CSRs) Prepared by the Scientific Registry of Transplant Recipients (SRTR)

Center: Avera McKennan Hospital (SDMK)

Organ: PA: Pancreas

Overview:

These Center-Specific Reports contain a wide range of useful information about transplant programs operating in the United States. The information includes many features of the transplant program, such as the number of transplants performed in recent years, waiting time and waiting list outcomes, and post-transplant experience of patients served by this center. The statistics are arranged to allow comparisons to national averages, as well as to the experience for similar patients at other centers in the country. This report is based largely on data submitted by this transplant center for patients on the waiting list and those transplanted within the last five years.

Table 1 provides a picture of the volume and type of waiting list and transplant activity at this center. Avera McKennan Hospital (SDMK) had 0 patients on its waiting list on 07/01/2002 and 1 patient on 06/30/2004. During these two years, 7 patients were added to the list and 6 patients were removed. Of the removals, 6 were for transplant from a deceased donor. Avera McKennan Hospital (SDMK) performed 6 pancreas transplants (Table 7) during the last year (07/01/2003-06/30/2004). Typical pancreas programs currently operating in the United States transplanted between 2 and 6 people in that same period. More about the activity at this center and the types of patients served is found in the Table Details section below and in Tables 1 and 2 (waiting list) and Tables 7, 8, and 9 (transplant).

Waiting times for transplantation differ from facility to facility and also from person to person, depending upon many factors. Half of the patients listed at this center had received a transplant as of 2.2 months after being placed on the waiting list; in the nation it took 13.5 months to reach the same fraction of patients transplanted. The other half of the patients were either still waiting or removed from the waiting list for reasons including death. Tables 3 through 5, which focus on other characteristics of waiting list and waiting time (including risk-adjusted comparisons) are discussed in the details section below.

At Avera McKennan Hospital (SDMK), 100.00 percent of patients were alive one year after transplant. For the nation as a whole, the percent was 95.74. A comparison between these is not risk-adjusted; that is, it does not account for differences in the types of patients served at this program.

Specific circumstances at each center may affect many of the measures reported in these reports. Frequently, staff from transplant programs make public comments regarding these reports, made available in the comments page. We encourage all readers of these reports to consider these comments and to contact the program directly for further information.

Table Details:

The above overview provides most readers with a quick look at some of the statistics that help describe a transplant program. The following section, for the more interested reader, provides a more detailed accounting of each table and how figures are defined and calculated.

Tables 1 through 6 focus on characteristics of the waiting list process at this center. Table 1 provides an overview of the waiting list activity at this center: not just the size of the waiting list at a given point in time, but also how many people have moved on to and off of this waiting list, and for what reasons. Shown as a percent of the total waiting list size on 07/01/2003, the percent of people removed for a transplant from a deceased donor was 39.9% nationwide, and the percent of people removed because of death was 2.6% nationwide (Note: Center specific numbers are not shown here because this center did not have anyone on the waiting list as of 07/01/2003). Table 2 shows the characteristics of patients on the waiting list at Avera McKennan Hospital (SDMK).

The waiting time at a given transplant center is affected by many factors, including the medical condition and characteristics of the patients listed with this center (Table 2), the availability of organs in the Donation Service Area served by the OPO, and decisions by medical professionals and other patients about organ acceptance. Some of the variability in waiting time may be accounted for by local availability of organs, in which case other centers in the Donation Service Area served by LifeSource Upper Midwest OPO may have similar waiting times.

Tables 3 through 6 provide different measures of looking at waiting list outcomes. Table 3 shows a 'risk-adjusted' comparison of two outcomes from the waiting list: transplant rate and death rate. While the national average transplant rate (from deceased donors) is 0.38 transplants per patient year, the rate expected for this center is 0.96. The difference, or 'adjustment', between the national average and expected rate is caused by the fact that this center may treat patients who typically have longer (or shorter) waiting times, based on the characteristics of these patients. The patients on the waiting list at this center experienced a transplant rate of 3.53 per year spent on the waiting list for any person(s) on the waiting list. Compared to the expected rate of 0.96, the difference is unlikely to have occured by random chance (p=.013) and probably represents a real difference from the expected rate.

These waiting list rates are measured as the number of transplants (or deaths) per year that any patient spends on the waiting list. It is possible for these rates to be above 1, as would be the case if 2 patients each spent 3 months on the waiting list, and one received a transplant: 1 transplant divided by .5 year = transplant rate of 2.

While Table 3 provides a waiting list outcome rate that allows easy comparison of risk-adjusted outcomes, statistics from tables 4 through 6 may be more interpretable at a patient level. Table 4 answers the questions: 'What has been the outcome for patients at this center 6 months after being placed on the waiting list? What about at 12 or 18 months?' The table also examines post-transplant outcomes: at 12 months, for example, the table tells if the patient is still on the waiting list, was transplanted and is still alive, or died after transplant.

Table 5 provides another way to look at how quickly patients receive transplants at this center, this time looking at many different kinds of patients. For this center, this table is not produced because it had no new patients on the waiting list during the relevant timeframe.

Table 6 shows the time it takes for a given percentage of patients at this facility to receive a transplant. This is the 'time-to-transplant' among all wait-listed patients, including those who never receive a transplant. Half of the patients placed on the waiting list at this center had received a transplant as of 2.2 months after listing; in the nation it took 13.5 months to reach the same fraction. The other half of the patients were either still waiting or removed from the waiting list, for reasons including death. (Another common statistic, 'median waiting time,' differs in that it is often calculated only among patients who actually received a transplant. The two are often correlated, but different in magnitude. While median waiting time reflects time waiting among successful candidates, time-to-transplant incorporates a measure of the probability of success in receiving an organ.)

The remainder of the tables, 7 through 11, focus on transplants performed at Avera McKennan Hospital (SDMK) and their outcomes. Tables 7-9 describe the characteristics of transplant recipients, donors, and operations at this center.

Tables 10 and 11 show post-transplant outcomes. Table 10 shows the survival experience of grafts (transplants) in patients transplanted by this center. Table 11 shows the survival experience of these patients themselves. These may be different because a patient may continue survival after a graft fails through means such as a new transplant, or, for kidney patients, dialysis. For each outcome, these tables show an actual (observed) survival for the center and for the nation. No risk-adjusted survival is presented. Each survival number measures the percentage of patients who have a functioning graft (Table 10) or who are alive (Table 11) at 1 month, 1 year, and 3 years after transplant.

For some organs, an 'expected' survival is not calculated because the characteristics influencing expected survival are not well known.