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Table 9.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1997 to 2006

Recipients with Liver Transplants

  Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Transplants 4,188 4,516 4,751 4,997 5,195 5,332 5,673 6,170 6,443 6,650
Tx with Follow-up Immunosuppression Info 3,182 3,479 3,641 3,890 4,091 4,305 4,569 4,940 5,058 5,297
Corticosteroids Any in Category 95.0% 93.0% 89.3% 90.5% 89.4% 87.2% 78.5% 75.4% 75.4% 71.8%
Steroids 95.0% 93.0% 89.3% 90.5% 89.4% 87.2% 78.5% 75.4% 75.4% 71.8%
Cyclosporine Any in Category 39.8% 33.4% 30.4% 23.4% 18.4% 14.0% 11.8% 11.6% 10.4% 9.9%
Cyclosporin 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1%
Sandimmmune 5.7% 7.0% 7.0% 5.4% 3.7% 2.0% 0.7% 0.9% 1.1% 1.2%
Neoral 34.1% 26.3% 23.3% 17.2% 13.3% 9.8% 8.9% 9.2% 7.8% 6.7%
Gengraf 0.0% 0.0% 0.1% 0.5% 1.3% 2.0% 1.8% 1.3% 1.3% 1.7%
Eon 0.0% 0.0% 0.0% 0.1% 0.2% 0.2% 0.3% 0.2% 0.1% 0.2%
Tacrolimus Any in Category 66.3% 73.4% 76.7% 84.1% 89.0% 90.5% 90.5% 89.7% 91.6% 90.8%
Tacrolimus 66.3% 73.4% 76.7% 84.1% 89.0% 90.5% 90.5% 89.7% 91.6% 90.8%
Antimetabolites Any in Category 44.4% 40.3% 49.3% 52.2% 53.5% 53.7% 55.1% 59.0% 66.3% 69.7%
Mycophenolate Mofetil 25.9% 29.7% 40.8% 46.2% 48.8% 49.3% 52.4% 55.5% 62.2% 64.3%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 2.9% 4.4%
Azathioprine 18.2% 10.5% 8.3% 5.9% 4.6% 4.3% 2.7% 3.0% 1.2% 1.0%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.3% 0.0% 0.1% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 1.2% 3.2% 15.1% 16.6% 13.8% 12.2% 14.1% 13.8% 11.9%
Sirolimus 0.0% 1.2% 3.1% 15.1% 16.6% 13.8% 12.2% 14.1% 13.8% 11.9%
Everolimus 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2008.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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