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Table 9.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1998 to 2007

Recipients with Liver Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Functioning Graft at Discharge 3,928 4,093 4,322 4,571 4,778 5,120 5,622 5,863 6,128 6,005
With Immunosuppression Info 3,742 3,943 4,304 4,564 4,774 5,114 5,594 5,792 6,062 5,902
Corticosteroids Any in Category 94.5% 93.0% 91.9% 90.2% 90.4% 82.4% 80.6% 78.9% 78.4% 75.9%
Steroids 94.5% 93.0% 91.9% 90.2% 90.4% 82.4% 80.6% 78.9% 78.4% 75.9%
Cyclosporine Any in Category 31.1% 25.9% 18.5% 11.9% 10.2% 8.7% 8.1% 7.0% 6.7% 7.2%
Cyclosporin 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.1%
Sandimmmune 4.0% 3.8% 3.1% 1.3% 1.1% 0.4% 0.5% 0.6% 0.8% 0.9%
Neoral 27.0% 22.1% 15.3% 9.7% 7.4% 7.4% 6.6% 5.6% 4.3% 5.1%
Gengraf 0.0% 0.0% 0.1% 0.6% 1.5% 0.8% 0.8% 0.6% 1.0% 0.8%
Eon 0.0% 0.0% 0.0% 0.4% 0.2% 0.1% 0.2% 0.1% 0.5% 0.3%
Tacrolimus Any in Category 67.1% 71.6% 76.6% 83.1% 86.8% 88.8% 88.7% 90.8% 91.3% 90.7%
Tacrolimus 67.1% 71.6% 76.6% 83.1% 86.8% 88.8% 88.7% 90.8% 91.3% 90.7%
Antimetabolites Any in Category 42.1% 44.5% 48.3% 50.8% 51.6% 57.3% 58.3% 61.4% 69.1% 72.8%
Mycophenolate Mofetil 30.3% 36.7% 43.3% 47.7% 48.1% 54.1% 55.8% 58.5% 65.0% 67.2%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 2.1% 3.7% 4.9%
Azathioprine 11.6% 7.7% 5.0% 3.0% 3.5% 3.2% 2.1% 0.7% 0.4% 0.6%
Leflunomide 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.2% 0.1% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.8% 0.6% 9.4% 9.9% 6.6% 4.4% 4.9% 4.0% 3.7% 2.5%
Sirolimus 0.8% 0.5% 9.4% 9.9% 6.6% 4.4% 4.9% 4.0% 3.7% 2.5%
Everolimus 0.0% 0.2% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2008.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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