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Table 9.6d

Immunosuppression Use for Maintenance by Regimen

Prior to Discharge, 1998 to 2007

Recipients with Liver Transplants

  Transplant Year
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Functioning Graft at Discharge 3,928 4,093 4,322 4,571 4,778 5,120 5,622 5,863 6,128 6,005
With Immunosuppression Info 3,742 3,943 4,304 4,564 4,774 5,114 5,594 5,792 6,062 5,902
CyA 1.7% 1.2% 0.2% 0.7% 0.2% 0.4% 0.2% 0.2% 0.1% 0.1%
Tac 2.1% 2.2% 1.4% 3.4% 4.8% 7.6% 9.8% 10.0% 5.5% 4.7%
--- + MMF/MPA 0.1% 0.1% 0.0% 0.1% 0.1% 0.3% 0.3% 0.2% 0.4% 0.3%
CyA + MMF/MPA 0.1% 0.3% 0.3% 0.2% 0.2% 0.4% 0.8% 0.6% 0.9% 1.2%
Tac + MMF/MPA 0.7% 1.6% 2.5% 2.6% 2.8% 6.5% 6.3% 8.4% 12.8% 15.7%
--- + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet 0.1% 0.3% 0.0% 0.0% 0.1% 0.5% 0.5% 0.0% 0.0% 0.0%
Tac + OtherAntimet 0.1% 0.2% 0.1% 0.1% 0.0% 0.3% 0.3% 0.3% 0.1% 0.2%
CyA + MMF/MPA + OtherAntimet 0.0% 0.2% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.1% 0.2% 0.1% 0.1%
CyA + Siro/Evero 0.1% 0.0% 0.7% 0.4% 0.0% 0.0% 0.0% 0.3% 0.6% 0.5%
Tac + Siro/Evero 0.0% 0.0% 1.0% 1.1% 0.4% 0.2% 0.4% 0.1% 0.2% 0.1%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.1% 0.2% 0.1% 0.1% 0.2% 0.2%
CyA + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.1%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.2% 0.1% 0.2% 0.1% 0.1% 0.1% 0.1%
--- + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Steroids 1.8% 1.7% 2.8% 2.2% 0.8% 0.8% 1.4% 0.8% 0.7% 0.8%
CyA + Steroids 13.5% 9.7% 6.1% 2.6% 2.1% 1.4% 1.0% 1.1% 0.5% 0.7%
Tac + Steroids 36.8% 38.9% 32.1% 32.3% 35.4% 29.4% 26.2% 24.1% 21.5% 19.2%
--- + MMF/MPA + Steroids 1.1% 1.1% 0.6% 0.9% 0.9% 0.9% 1.2% 0.9% 1.0% 1.1%
CyA + MMF/MPA + Steroids 6.9% 8.5% 6.6% 5.5% 4.6% 3.8% 3.3% 3.1% 3.0% 3.0%
Tac + MMF/MPA + Steroids 20.6% 24.1% 30.5% 35.1% 36.6% 39.5% 41.4% 44.8% 48.1% 48.6%
--- + OtherAntimet + Steroids 0.3% 0.3% 0.0% 0.0% 0.0% 0.3% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Steroids 5.9% 3.7% 2.6% 1.2% 1.2% 0.1% 0.5% 0.2% 0.1% 0.1%
Tac + OtherAntimet + Steroids 4.8% 2.7% 1.9% 1.4% 2.0% 1.8% 0.6% 0.1% 0.1% 0.2%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.4% 0.4% 0.4% 0.2% 0.3% 0.2% 0.2% 0.2%
CyA + Siro/Evero + Steroids 0.6% 0.3% 0.4% 0.3% 0.6% 0.5% 0.4% 0.3% 0.1% 0.1%
Tac + Siro/Evero + Steroids 0.0% 0.1% 4.6% 4.6% 2.6% 1.0% 1.4% 0.9% 1.0% 0.4%
Other Regimen 2.8% 3.0% 5.0% 4.7% 3.9% 3.4% 3.1% 2.8% 2.4% 2.3%


Source: OPTN/SRTR Data as of May 1, 2008.

Percentages in each column sum to 100 percent.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.



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