Table 7.6h

Persistency of Discharge Regimen by Follow-up Period, 2001 to 2005

Recipients with Pancreas After Kidney (PAK) Transplants

  Year of Transplant
2001 2002 2003 2004 2005
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) - - 1 - -
At Discharge (%) - - 100.0% - -
6 Months PostTx (%) - - 0.0% - -
1 Year PostTx (%) - - 0.0% - -
2 Years PostTx (%) - - 0.0% - -
3 Years PostTx (%) - - 0.0% - -
CyA+MMF At Discharge (N) 18 25 19 18 13
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 70.8% 62.5% 68.4% 94.1% 69.2%
1 Year PostTx (%) 51.5% 62.5% 57.9% 75.6% 53.8%
2 Years PostTx (%) 25.8% 62.5% 46.8% 69.3% -
3 Years PostTx (%) 25.8% 62.5% 46.8% - -
CyA+Siro At Discharge (N) 4 7 4 7 5
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 75.0% 100.0% 75.0% 71.4% 60.0%
1 Year PostTx (%) 50.0% 100.0% 50.0% 42.9% 20.0%
2 Years PostTx (%) 50.0% 55.6% 50.0% 14.3% -
3 Years PostTx (%) 50.0% 27.8% 0.0% - -
Siro+MMF At Discharge (N) 1 1 6 9 5
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 0.0% 0.0% 83.3% 75.0% 80.0%
1 Year PostTx (%) 0.0% 0.0% 83.3% 62.5% 53.3%
2 Years PostTx (%) 0.0% 0.0% 83.3% 62.5% -
3 Years PostTx (%) 0.0% 0.0% 41.7% 62.5% -
Tac+Aza At Discharge (N) 2 1 1 1 3
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 50.0% 0.0% 100.0% 100.0% 33.3%
1 Year PostTx (%) 0.0% 0.0% 0.0% 100.0% 33.3%
2 Years PostTx (%) 0.0% 0.0% 0.0% 0.0% -
3 Years PostTx (%) 0.0% 0.0% 0.0% 0.0% -
Tac+MMF At Discharge (N) 180 207 207 236 215
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 80.9% 79.4% 74.2% 79.6% 87.9%
1 Year PostTx (%) 74.1% 63.6% 63.1% 71.3% 80.4%
2 Years PostTx (%) 60.5% 55.9% 54.8% 60.5% 71.5%
3 Years PostTx (%) 54.4% 51.6% 50.9% 60.5% -
Tac+Siro At Discharge (N) 47 46 26 33 21
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 83.0% 71.2% 65.4% 75.2% 65.2%
1 Year PostTx (%) 70.2% 53.4% 49.5% 59.5% 65.2%
2 Years PostTx (%) 63.4% 42.3% 31.7% 59.5% -
3 Years PostTx (%) 58.9% 37.3% 27.2% - -


Source: OPTN/SRTR Data as of May 1, 2007.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen (CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.