Table 7.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1996 to 2005

Recipients with Pancreas After Kidney (PAK) Transplants

  Year of Transplant
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Transplants 113 130 156 220 304 305 375 344 420 343
Tx with Follow-up Immunosuppression Info 71 89 110 168 219 245 271 258 318 257
Corticosteroids Any in Category 100.0% 100.0% 100.0% 100.0% 99.1% 98.8% 94.5% 78.7% 73.6% 73.2%
Steroids 100.0% 100.0% 100.0% 100.0% 99.1% 98.8% 94.5% 78.7% 73.6% 73.2%
Cyclosporine Any in Category 45.1% 21.3% 32.7% 14.3% 16.0% 15.1% 15.5% 11.2% 8.2% 6.6%
Sandimmmune 7.0% 4.5% 5.5% 2.4% 3.2% 0.8% 1.1% 0.0% 0.3% 0.0%
Neoral 38.0% 16.9% 27.3% 11.9% 11.9% 12.7% 12.2% 9.3% 5.0% 6.2%
Gengraf 0.0% 0.0% 0.0% 0.0% 0.9% 0.8% 2.2% 1.6% 2.8% 0.4%
Eon 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 0.0% 0.4% 0.0% 0.0%
Tacrolimus Any in Category 67.6% 88.8% 76.4% 91.1% 91.8% 91.8% 87.1% 82.9% 87.4% 92.6%
Tacrolimus 67.6% 88.8% 76.4% 91.1% 91.8% 91.8% 87.1% 82.9% 87.4% 92.6%
Antimetabolites Any in Category 100.0% 100.0% 99.1% 95.2% 84.5% 80.4% 80.4% 84.9% 82.1% 89.1%
Mycophenolate Mofetil 83.1% 89.9% 89.1% 86.3% 78.5% 78.0% 78.2% 81.0% 78.9% 82.9%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.2% 4.3%
Azathioprine 16.9% 10.1% 10.0% 8.9% 5.9% 2.4% 2.2% 3.5% 0.3% 1.9%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.6% 0.0%
Cytoxan 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.0% 0.9% 7.1% 24.7% 30.6% 31.7% 27.5% 25.8% 19.5%
Sirolimus 0.0% 0.0% 0.9% 7.1% 24.7% 30.6% 31.7% 27.5% 25.8% 19.5%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.