Table 7.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1996 to 2005

Recipients with Pancreas After Kidney (PAK) Transplants

  Transplant Year
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Transplants 113 130 156 220 304 305 375 344 420 343
Functioning Graft at 1 Year PostTx 71 89 110 168 219 245 271 259 320 258
With Maintenance Use Recorded at 1 Year PostTx 3 19 70 164 211 242 266 251 317 256
--- + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 1.6% 3.2% 0.0%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 0.3% 1.6%
--- + MMF/MPA + Steroids 0.0% 0.0% 0.0% 0.6% 0.5% 0.4% 0.4% 0.0% 0.3% 0.4%
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.3% 0.0%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.6% 0.5% 0.8% 0.4% 0.4% 0.0% 0.0%
--- + Steroids 0.0% 0.0% 0.0% 0.0% 0.5% 0.0% 0.0% 0.4% 0.0% 0.0%
CyA + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.8% 0.8% 0.9% 1.2%
CyA + MMF/MPA + Steroids 33.3% 10.5% 22.9% 9.1% 8.1% 8.3% 9.8% 5.2% 4.1% 2.0%
CyA + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Steroids 0.0% 0.0% 1.4% 0.6% 0.5% 0.0% 0.4% 0.0% 0.0% 0.4%
CyA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 0.4%
CyA + Siro/Evero + Steroids 0.0% 0.0% 1.4% 1.8% 2.8% 1.2% 1.9% 0.8% 0.6% 0.8%
CyA + Steroids 0.0% 0.0% 1.4% 0.0% 0.9% 0.4% 0.4% 1.2% 0.0% 0.4%
Tac 0.0% 0.0% 0.0% 0.0% 0.9% 0.0% 0.8% 1.6% 5.4% 3.1%
Tac + MMF/MPA 0.0% 0.0% 0.0% 1.2% 2.8% 4.1% 3.4% 7.6% 8.5% 18.8%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 1.2% 1.3% 2.3%
Tac + MMF/MPA + Steroids 66.7% 73.7% 62.9% 73.2% 54.5% 55.4% 53.0% 45.8% 50.5% 53.9%
Tac + OtherAntimet 0.0% 0.0% 1.4% 0.0% 0.9% 0.0% 0.0% 0.8% 0.0% 0.4%
Tac + OtherAntimet + Steroids 0.0% 10.5% 4.3% 4.3% 2.4% 0.8% 0.4% 1.6% 0.9% 0.8%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.9% 4.1% 7.5% 4.4% 7.3% 4.7%
Tac + Siro/Evero + Steroids 0.0% 0.0% 0.0% 3.7% 14.7% 15.3% 10.9% 10.0% 7.3% 4.3%
Tac + Steroids 0.0% 5.3% 1.4% 3.7% 4.7% 4.1% 4.1% 3.2% 2.2% 0.8%
Other Regimen 0.0% 0.0% 2.9% 1.2% 4.3% 4.1% 5.3% 12.7% 6.3% 3.9%


Source: OPTN/SRTR Data as of May 1, 2007.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.