Table 15.6

Steroid Avoidance Rate at Discharge, 1997 to 2006

Recipients of Heart Transplants

Discharge Regimen Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Total Patients 1,990 2,040 1,849 1,909 1,914 1,905 1,817 1,772 1,850 1,905
Steroids Avoided 87 79 80 102 54 56 134 140 120 150
Rate 4.4% 3.9% 4.3% 5.3% 2.8% 2.9% 7.4% 7.9% 6.5% 7.9%
CyA Patients 98 86 216 89 37 47 34 13 14 26
Steroids Avoided 7 6 10 13 6 1 2 2 2 3
Rate 7.1% 7.0% 4.6% 14.6% 16.2% 2.1% 5.9% 15.4% 14.3% 11.5%
Tac Patients 50 38 43 41 68 75 60 38 44 46
Steroids Avoided 1 2 2 2 5 2 7 3 7 11
Rate 2.0% 5.3% 4.7% 4.9% 7.4% 2.7% 11.7% 7.9% 15.9% 23.9%
CyA+MMF Patients 461 693 748 1,078 1,011 825 805 735 615 590
Steroids Avoided 13 21 18 37 18 15 37 34 30 36
Rate 2.8% 3.0% 2.4% 3.4% 1.8% 1.8% 4.6% 4.6% 4.9% 6.1%
Tac+MMF Patients 49 120 151 161 371 460 540 685 894 994
Steroids Avoided 1 6 1 5 7 16 48 47 48 71
Rate 2.0% 5.0% 0.7% 3.1% 1.9% 3.5% 8.9% 6.9% 5.4% 7.1%
CyA+Aza Patients 1,097 821 478 301 204 136 92 83 49 42
Steroids Avoided 47 29 14 21 9 11 10 14 7 3
Rate 4.3% 3.5% 2.9% 7.0% 4.4% 8.1% 10.9% 16.9% 14.3% 7.1%
Tac+Aza Patients 61 49 36 39 25 25 24 22 19 26
Steroids Avoided 0 1 3 1 1 2 2 4 4 1
Rate 0.0% 2.0% 8.3% 2.6% 4.0% 8.0% 8.3% 18.2% 21.1% 3.8%
Siro+MMF Patients - - - - 4 7 18 19 15 22
Steroids Avoided - - - - 0 0 1 2 1 1
Rate - - - - 0.0% 0.0% 5.6% 10.5% 6.7% 4.5%
CyA+Siro Patients - 1 11 12 3 18 38 2 1 1
Steroids Avoided - 0 0 1 0 1 1 0 0 0
Rate - 0.0% 0.0% 8.3% 0.0% 5.6% 2.6% 0.0% 0.0% 0.0%
Tac+Siro Patients - - 2 17 39 108 32 15 21 19
Steroids Avoided - - 0 0 0 3 1 2 6 8
Rate - - 0.0% 0.0% 0.0% 2.8% 3.1% 13.3% 28.6% 42.1%
Other Regimen Patients 174 232 164 171 152 204 174 160 178 139
Steroids Avoided 18 14 32 22 8 5 25 32 15 16
Rate 10.3% 6.0% 19.5% 12.9% 5.3% 2.5% 14.4% 20.0% 8.4% 11.5%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.