Table 15.5b

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2004

Recipients of Living Donor Livers

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002 2003 2004
Total Patients 48 132 246 341 235 191 181
Steroids Withdrawn 17 59 132 222 147 121 119
Rate 35.4% 44.7% 53.7% 65.1% 62.6% 63.4% 65.7%
CyA Patients 5 10 13 5 5 6 -
Steroids Withdrawn 1 6 9 3 5 4 -
Rate 20.0% 60.0% 69.2% 60.0% 100.0% 66.7% -
Tac Patients 17 63 93 121 89 64 60
Steroids Withdrawn 10 29 49 76 59 33 41
Rate 58.8% 46.0% 52.7% 62.8% 66.3% 51.6% 68.3%
CyA+MMF Patients 5 6 14 20 13 13 9
Steroids Withdrawn 1 3 4 16 10 12 8
Rate 20.0% 50.0% 28.6% 80.0% 76.9% 92.3% 88.9%
Tac+MMF Patients 17 37 92 142 98 99 94
Steroids Withdrawn 3 17 53 98 57 67 59
Rate 17.6% 45.9% 57.6% 69.0% 58.2% 67.7% 62.8%
CyA+Aza Patients 1 3 3 1 4 2 2
Steroids Withdrawn 0 0 1 0 2 1 2
Rate 0.0% 0.0% 33.3% 0.0% 50.0% 50.0% 100.0%
Tac+Aza Patients - 4 2 - 2 - -
Steroids Withdrawn - 1 1 - 2 - -
Rate - 25.0% 50.0% - 100.0% - -
Siro+MMF Patients - - 1 3 2 - 1
Steroids Withdrawn - - 0 0 2 - 1
Rate - - 0.0% 0.0% 100.0% - 100.0%
CyA+Siro Patients - - 2 3 1 - 1
Steroids Withdrawn - - 1 3 1 - 1
Rate - - 50.0% 100.0% 100.0% - 100.0%
Tac+Siro Patients - - 10 22 9 1 2
Steroids Withdrawn - - 7 13 5 1 2
Rate - - 70.0% 59.1% 55.6% 100.0% 100.0%
Other Regimen Patients 3 9 16 24 12 6 12
Steroids Withdrawn 2 3 7 13 4 3 5
Rate 66.7% 33.3% 43.8% 54.2% 33.3% 50.0% 41.7%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.