Table 15.5a

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2004

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002 2003 2004
Total Patients 2,478 2,487 2,815 2,772 2,973 2,955 3,162
Steroids Withdrawn 1,164 1,343 1,726 1,804 1,980 2,001 2,132
Rate 47.0% 54.0% 61.3% 65.1% 66.6% 67.7% 67.4%
CyA Patients 373 268 181 88 69 47 37
Steroids Withdrawn 121 125 101 57 53 28 27
Rate 32.4% 46.6% 55.8% 64.8% 76.8% 59.6% 73.0%
Tac Patients 923 1,008 966 988 1,184 1,065 1,069
Steroids Withdrawn 511 590 654 677 802 750 688
Rate 55.4% 58.5% 67.7% 68.5% 67.7% 70.4% 64.4%
CyA+MMF Patients 189 241 209 169 130 120 127
Steroids Withdrawn 71 108 88 88 72 70 84
Rate 37.6% 44.8% 42.1% 52.1% 55.4% 58.3% 66.1%
Tac+MMF Patients 535 641 945 1,091 1,209 1,419 1,603
Steroids Withdrawn 306 389 588 706 815 969 1,112
Rate 57.2% 60.7% 62.2% 64.7% 67.4% 68.3% 69.4%
CyA+Aza Patients 170 119 95 46 37 1 22
Steroids Withdrawn 40 38 47 30 19 0 14
Rate 23.5% 31.9% 49.5% 65.2% 51.4% 0.0% 63.6%
Tac+Aza Patients 143 82 60 58 72 75 24
Steroids Withdrawn 48 29 25 32 46 45 17
Rate 33.6% 35.4% 41.7% 55.2% 63.9% 60.0% 70.8%
Siro+MMF Patients - 2 23 38 32 29 28
Steroids Withdrawn - 0 17 28 22 22 22
Rate - 0.0% 73.9% 73.7% 68.8% 75.9% 78.6%
CyA+Siro Patients 18 2 10 7 20 16 18
Steroids Withdrawn 15 2 7 3 13 9 15
Rate 83.3% 100.0% 70.0% 42.9% 65.0% 56.3% 83.3%
Tac+Siro Patients - 4 129 118 85 40 49
Steroids Withdrawn - 1 84 84 66 27 30
Rate - 25.0% 65.1% 71.2% 77.6% 67.5% 61.2%
Other Regimen Patients 127 120 197 169 135 143 185
Steroids Withdrawn 52 61 115 99 72 81 123
Rate 40.9% 50.8% 58.4% 58.6% 53.3% 56.6% 66.5%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.