Table 15.5a

Steroid Avoidance Rate at Discharge, 1997 to 2006

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Total Patients 3,029 3,357 3,422 3,621 3,748 4,059 4,435 4,889 5,028 5,311
Steroids Avoided 153 179 242 296 370 405 771 955 1,063 1,144
Rate 5.1% 5.3% 7.1% 8.2% 9.9% 10.0% 17.4% 19.5% 21.1% 21.5%
CyA Patients 514 525 372 226 117 97 76 59 64 36
Steroids Avoided 27 59 36 6 18 11 20 10 12 7
Rate 5.3% 11.2% 9.7% 2.7% 15.4% 11.3% 26.3% 16.9% 18.8% 19.4%
Tac Patients 1,048 1,298 1,380 1,194 1,338 1,646 1,639 1,761 1,693 1,370
Steroids Avoided 49 67 79 52 129 195 331 485 505 278
Rate 4.7% 5.2% 5.7% 4.4% 9.6% 11.8% 20.2% 27.5% 29.8% 20.3%
CyA+MMF Patients 197 237 315 258 211 186 179 194 188 217
Steroids Avoided 13 4 9 11 7 8 19 40 28 52
Rate 6.6% 1.7% 2.9% 4.3% 3.3% 4.3% 10.6% 20.6% 14.9% 24.0%
Tac+MMF Patients 501 711 882 1,204 1,433 1,594 2,050 2,336 2,707 3,284
Steroids Avoided 24 21 56 95 107 124 284 302 433 685
Rate 4.8% 3.0% 6.3% 7.9% 7.5% 7.8% 13.9% 12.9% 16.0% 20.9%
CyA+Aza Patients 324 210 147 109 51 56 24 51 12 5
Steroids Avoided 4 5 12 1 0 6 22 26 0 0
Rate 1.2% 2.4% 8.2% 0.9% 0.0% 10.7% 91.7% 51.0% 0.0% 0.0%
Tac+Aza Patients 154 163 100 76 65 88 100 47 21 11
Steroids Avoided 1 2 5 3 4 2 13 19 17 5
Rate 0.6% 1.2% 5.0% 3.9% 6.2% 2.3% 13.0% 40.4% 81.0% 45.5%
Siro+MMF Patients - - 2 28 48 46 43 42 45 43
Steroids Avoided - - 0 1 0 3 8 5 6 12
Rate - - 0.0% 3.6% 0.0% 6.5% 18.6% 11.9% 13.3% 27.9%
CyA+Siro Patients - 26 3 37 25 25 23 23 31 42
Steroids Avoided - 5 0 24 16 1 0 2 13 39
Rate - 19.2% 0.0% 64.9% 64.0% 4.0% 0.0% 8.7% 41.9% 92.9%
Tac+Siro Patients - - 4 194 198 107 54 85 51 65
Steroids Avoided - - 0 34 34 15 8 22 5 10
Rate - - 0.0% 17.5% 17.2% 14.0% 14.8% 25.9% 9.8% 15.4%
Other Regimen Patients 291 187 217 295 262 214 247 291 216 238
Steroids Avoided 35 16 45 69 55 40 66 44 44 56
Rate 12.0% 8.6% 20.7% 23.4% 21.0% 18.7% 26.7% 15.1% 20.4% 23.5%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.