Table 15.4b

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2004

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002 2003 2004
Total Patients 2,993 3,258 3,859 4,090 4,104 3,896 3,536
Steroids Withdrawn 200 184 270 382 528 567 567
Rate 6.7% 5.6% 7.0% 9.3% 12.9% 14.6% 16.0%
CyA Patients 190 197 141 93 63 75 77
Steroids Withdrawn 13 11 10 12 3 4 6
Rate 6.8% 5.6% 7.1% 12.9% 4.8% 5.3% 7.8%
Tac Patients 74 92 143 150 124 116 116
Steroids Withdrawn 11 13 21 23 16 18 24
Rate 14.9% 14.1% 14.7% 15.3% 12.9% 15.5% 20.7%
CyA+MMF Patients 1,540 1,663 1,639 1,356 1,078 824 710
Steroids Withdrawn 76 74 57 73 74 54 64
Rate 4.9% 4.4% 3.5% 5.4% 6.9% 6.6% 9.0%
Tac+MMF Patients 557 793 1,125 1,613 2,046 2,125 2,045
Steroids Withdrawn 39 50 96 167 266 325 340
Rate 7.0% 6.3% 8.5% 10.4% 13.0% 15.3% 16.6%
CyA+Aza Patients 318 219 163 126 44 19 10
Steroids Withdrawn 27 8 7 4 2 0 0
Rate 8.5% 3.7% 4.3% 3.2% 4.5% 0.0% 0.0%
Tac+Aza Patients 54 51 50 65 72 62 34
Steroids Withdrawn 15 10 13 17 17 4 5
Rate 27.8% 19.6% 26.0% 26.2% 23.6% 6.5% 14.7%
Siro+MMF Patients 2 1 29 89 115 106 71
Steroids Withdrawn 0 0 1 2 23 20 12
Rate 0.0% 0.0% 3.4% 2.2% 20.0% 18.9% 16.9%
CyA+Siro Patients 71 47 227 149 101 99 40
Steroids Withdrawn 6 3 26 13 34 32 3
Rate 8.5% 6.4% 11.5% 8.7% 33.7% 32.3% 7.5%
Tac+Siro Patients - 4 159 278 258 223 153
Steroids Withdrawn - 1 14 47 58 53 29
Rate - 25.0% 8.8% 16.9% 22.5% 23.8% 19.0%
Other Regimen Patients 187 191 183 171 203 247 280
Steroids Withdrawn 13 14 25 24 35 57 84
Rate 7.0% 7.3% 13.7% 14.0% 17.2% 23.1% 30.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.