Table 15.4b

Steroid Withdrawal Rate at One Year Following Transplantation, 1999 to 2005

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005
Total Patients 3,446 3,893 4,392 4,376 4,111 3,738 3,442
Steroids Withdrawn 148 184 242 465 467 454 485
Rate 4.3% 4.7% 5.5% 10.6% 11.4% 12.1% 14.1%
CyA Patients 198 145 104 70 84 87 19
Steroids Withdrawn 5 6 4 3 3 2 1
Rate 2.5% 4.1% 3.8% 4.3% 3.6% 2.3% 5.3%
Tac Patients 97 141 158 134 117 123 78
Steroids Withdrawn 8 14 19 17 17 23 17
Rate 8.2% 9.9% 12.0% 12.7% 14.5% 18.7% 21.8%
CyA+MMF Patients 1,760 1,615 1,460 1,165 902 744 539
Steroids Withdrawn 68 47 38 70 35 43 35
Rate 3.9% 2.9% 2.6% 6.0% 3.9% 5.8% 6.5%
Tac+MMF Patients 849 1,162 1,739 2,161 2,229 2,198 2,330
Steroids Withdrawn 50 59 105 214 272 273 317
Rate 5.9% 5.1% 6.0% 9.9% 12.2% 12.4% 13.6%
CyA+Aza Patients 238 163 132 49 17 11 4
Steroids Withdrawn 6 4 0 3 0 1 0
Rate 2.5% 2.5% 0.0% 6.1% 0.0% 9.1% 0.0%
Tac+Aza Patients 56 49 67 74 62 34 6
Steroids Withdrawn 1 10 10 13 3 3 1
Rate 1.8% 20.4% 14.9% 17.6% 4.8% 8.8% 16.7%
Siro+MMF Patients 1 30 89 124 111 74 100
Steroids Withdrawn 0 1 0 17 10 5 21
Rate 0.0% 3.3% 0.0% 13.7% 9.0% 6.8% 21.0%
CyA+Siro Patients 50 231 156 108 101 42 43
Steroids Withdrawn 3 13 6 37 32 1 5
Rate 6.0% 5.6% 3.8% 34.3% 31.7% 2.4% 11.6%
Tac+Siro Patients 4 172 300 277 237 162 120
Steroids Withdrawn 0 11 40 54 41 28 18
Rate 0.0% 6.4% 13.3% 19.5% 17.3% 17.3% 15.0%
Other Regimen Patients 193 185 187 214 251 263 203
Steroids Withdrawn 7 19 20 37 54 75 70
Rate 3.6% 10.3% 10.7% 17.3% 21.5% 28.5% 34.5%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use one year after transplantation.

Transplants prior to year 1999 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.