Table 15.4a

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2004

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002 2003 2004
Total Patients 4,958 4,904 5,000 5,191 5,301 5,036 4,950
Steroids Withdrawn 278 287 283 427 511 540 634
Rate 5.6% 5.9% 5.7% 8.2% 9.6% 10.7% 12.8%
CyA Patients 294 269 170 77 71 77 80
Steroids Withdrawn 13 11 4 8 12 9 3
Rate 4.4% 4.1% 2.4% 10.4% 16.9% 11.7% 3.8%
Tac Patients 135 137 157 207 196 117 157
Steroids Withdrawn 20 14 20 34 33 24 49
Rate 14.8% 10.2% 12.7% 16.4% 16.8% 20.5% 31.2%
CyA+MMF Patients 2,576 2,431 2,033 1,573 1,387 1,096 927
Steroids Withdrawn 92 88 59 55 61 90 78
Rate 3.6% 3.6% 2.9% 3.5% 4.4% 8.2% 8.4%
Tac+MMF Patients 899 1,266 1,566 2,127 2,686 2,834 3,061
Steroids Withdrawn 71 103 125 207 262 283 402
Rate 7.9% 8.1% 8.0% 9.7% 9.8% 10.0% 13.1%
CyA+Aza Patients 457 285 199 100 44 23 13
Steroids Withdrawn 26 18 6 4 1 1 0
Rate 5.7% 6.3% 3.0% 4.0% 2.3% 4.3% 0.0%
Tac+Aza Patients 96 59 46 73 51 39 23
Steroids Withdrawn 7 12 14 9 14 7 1
Rate 7.3% 20.3% 30.4% 12.3% 27.5% 17.9% 4.3%
Siro+MMF Patients 0 8 63 173 192 148 116
Steroids Withdrawn - 0 3 10 18 24 21
Rate - 0.0% 4.8% 5.8% 9.4% 16.2% 18.1%
CyA+Siro Patients 168 73 248 234 147 139 87
Steroids Withdrawn 25 3 9 16 15 11 8
Rate 14.9% 4.1% 3.6% 6.8% 10.2% 7.9% 9.2%
Tac+Siro Patients - 8 214 310 209 263 173
Steroids Withdrawn - 0 15 46 37 38 11
Rate - 0.0% 7.0% 14.8% 17.7% 14.4% 6.4%
Other Regimen Patients 333 368 304 317 318 300 313
Steroids Withdrawn 24 38 28 38 58 53 61
Rate 7.2% 10.3% 9.2% 12.0% 18.2% 17.7% 19.5%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.