Table 15.4a

Steroid Withdrawal Rate at One Year Following Transplantation, 1999 to 2005

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005
Total Patients 5,370 5,204 5,684 5,745 5,468 5,422 5,344
Steroids Withdrawn 209 245 265 440 433 499 691
Rate 3.9% 4.7% 4.7% 7.7% 7.9% 9.2% 12.9%
CyA Patients 283 180 83 82 87 91 32
Steroids Withdrawn 14 20 2 9 6 2 1
Rate 4.9% 11.1% 2.4% 11.0% 6.9% 2.2% 3.1%
Tac Patients 150 159 231 213 129 169 196
Steroids Withdrawn 11 14 30 31 21 44 43
Rate 7.3% 8.8% 13.0% 14.6% 16.3% 26.0% 21.9%
CyA+MMF Patients 2,675 2,055 1,714 1,535 1,238 1,007 728
Steroids Withdrawn 68 51 36 54 72 65 44
Rate 2.5% 2.5% 2.1% 3.5% 5.8% 6.5% 6.0%
Tac+MMF Patients 1,376 1,671 2,334 2,864 3,028 3,370 3,725
Steroids Withdrawn 74 93 113 226 224 311 477
Rate 5.4% 5.6% 4.8% 7.9% 7.4% 9.2% 12.8%
CyA+Aza Patients 311 205 106 51 27 14 7
Steroids Withdrawn 9 3 2 2 1 0 0
Rate 2.9% 1.5% 1.9% 3.9% 3.7% 0.0% 0.0%
Tac+Aza Patients 67 49 78 56 42 23 12
Steroids Withdrawn 5 11 7 11 3 1 1
Rate 7.5% 22.4% 9.0% 19.6% 7.1% 4.3% 8.3%
Siro+MMF Patients 8 68 189 213 155 133 112
Steroids Withdrawn 0 2 8 9 19 14 8
Rate 0.0% 2.9% 4.2% 4.2% 12.3% 10.5% 7.1%
CyA+Siro Patients 92 270 251 158 150 94 81
Steroids Withdrawn 6 7 5 11 8 4 11
Rate 6.5% 2.6% 2.0% 7.0% 5.3% 4.3% 13.6%
Tac+Siro Patients 9 236 350 233 286 186 116
Steroids Withdrawn 0 15 32 32 23 5 15
Rate 0.0% 6.4% 9.1% 13.7% 8.0% 2.7% 12.9%
Other Regimen Patients 399 311 348 340 326 335 335
Steroids Withdrawn 22 29 30 55 56 53 91
Rate 5.5% 9.3% 8.6% 16.2% 17.2% 15.8% 27.2%


Source: OPTN/SRTR Data as of May 1, 2007.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use one year after transplantation.

Transplants prior to year 1999 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.