Table 14.6

De Novo Post Transplant Solid Malignancy, 1997 to 2006

Kidney Recipients

Malignancies by Type Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Total # of Post-Tx Malignancies 824 871 783 828 711 526 454 338 175 76
Squamous/Basal Cell Carcinoma 466 472 420 430 357 276 208 173 77 27
Melanoma 20 18 22 29 19 15 21 6 8 4
Kaposi Sarcoma 5 12 7 10 6 2 3 4 - 2
Central Nervous System 4 7 7 8 8 6 2 2 2 -
Genito-Urinary (1) 117 128 113 119 93 76 76 49 36 14
Gastro-Intestinal (2) 49 49 67 53 52 36 36 25 16 8
Primary Hepatic Tumor 8 9 4 9 8 6 2 3 1 5
Metastatic Hepatic Tumor 10 15 9 11 16 8 5 5 2 3
Larynx/Bronchi/Lung 50 63 61 57 65 33 39 27 15 4
Breast/Thyroid 44 47 34 44 43 29 29 17 6 4
Leukemia 4 3 3 5 7 6 2 4 3 1
Sarcoma (3) 1 3 2 2 4 - 3 2 - -
Other 37 42 26 40 26 25 13 19 6 2
Unknown 9 3 8 11 7 8 15 2 3 2
Squamous/Basal Cell Carcinoma 56.6% 54.2% 53.6% 51.9% 50.2% 52.5% 45.8% 51.2% 44.0% 35.5%
Melanoma 2.4% 2.1% 2.8% 3.5% 2.7% 2.9% 4.6% 1.8% 4.6% 5.3%
Kaposi Sarcoma 0.6% 1.4% 0.9% 1.2% 0.8% 0.4% 0.7% 1.2% - 2.6%
Central Nervous System 0.5% 0.8% 0.9% 1.0% 1.1% 1.1% 0.4% 0.6% 1.1% -
Genito-Urinary (1) 14.2% 14.7% 14.4% 14.4% 13.1% 14.4% 16.7% 14.5% 20.6% 18.4%
Gastro-Intestinal (2) 5.9% 5.6% 8.6% 6.4% 7.3% 6.8% 7.9% 7.4% 9.1% 10.5%
Primary Hepatic Tumor 1.0% 1.0% 0.5% 1.1% 1.1% 1.1% 0.4% 0.9% 0.6% 6.6%
Metastatic Hepatic Tumor 1.2% 1.7% 1.1% 1.3% 2.3% 1.5% 1.1% 1.5% 1.1% 3.9%
Larynx/Bronchi/Lung 6.1% 7.2% 7.8% 6.9% 9.1% 6.3% 8.6% 8.0% 8.6% 5.3%
Breast/Thyroid 5.3% 5.4% 4.3% 5.3% 6.0% 5.5% 6.4% 5.0% 3.4% 5.3%
Leukemia 0.5% 0.3% 0.4% 0.6% 1.0% 1.1% 0.4% 1.2% 1.7% 1.3%
Sarcoma (3) 0.1% 0.3% 0.3% 0.2% 0.6% - 0.7% 0.6% - -
Other 4.5% 4.8% 3.3% 4.8% 3.7% 4.8% 2.9% 5.6% 3.4% 2.6%
Unknown 1.1% 0.3% 1.0% 1.3% 1.0% 1.5% 3.3% 0.6% 1.7% 2.6%
Total # of Patients 567 619 563 582 526 408 353 269 153 69


Source: OPTN/SRTR Data as of May 1, 2007.

(-) = None in category.

(1) Genito-Urinary: kidney, bladder, uterine cervix, uterine body, ovarian, vulva, testicular, prostate.

(2) Gastro-Intestinal: tongue, throat, esophagus, stomach, small intestine, colo-rectal, liver and biliary tract, pancreas.

(3) Sarcoma: fibrosarcoma, osteosarcoma, etc.

Recipient malignancy statistics are based on voluntary reporting to the OPTN.