Table 12.6h

Persistency of Discharge Regimen by Follow-up Period, 2001 to 2005

Recipients with Lung Transplants

  Year of Transplant
2001 2002 2003 2004 2005
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) 256 198 167 179 154
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
1 Year PostTx (%) 50.2% 39.4% 45.2% 57.0% 74.4%
2 Years PostTx (%) 20.6% 22.5% 26.1% 28.4% 74.4%
3 Years PostTx (%) 12.3% 15.2% 20.5% - -
CyA+MMF At Discharge (N) 162 163 137 111 103
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
1 Year PostTx (%) 51.9% 46.6% 53.0% 57.7% 70.1%
2 Years PostTx (%) 30.0% 31.1% 36.2% 31.6% 70.1%
3 Years PostTx (%) 19.7% 22.1% 27.1% - -
CyA+Siro At Discharge (N) 1 3 1 - -
At Discharge (%) 100.0% 100.0% 100.0% - -
1 Year PostTx (%) 0.0% 66.7% 100.0% - -
2 Years PostTx (%) 0.0% 66.7% 100.0% - -
3 Years PostTx (%) 0.0% 66.7% - - -
Siro+MMF At Discharge (N) 2 1 1 4 2
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
1 Year PostTx (%) 0.0% 0.0% 0.0% 25.0% 50.0%
2 Years PostTx (%) 0.0% 0.0% 0.0% 25.0% -
3 Years PostTx (%) 0.0% 0.0% 0.0% - -
Tac+Aza At Discharge (N) 200 218 275 275 316
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
1 Year PostTx (%) 64.8% 55.6% 55.0% 67.2% 63.1%
2 Years PostTx (%) 47.1% 40.3% 36.7% 42.5% 57.8%
3 Years PostTx (%) 31.8% 31.2% 29.7% 42.5% -
Tac+MMF At Discharge (N) 177 240 283 393 568
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
1 Year PostTx (%) 68.4% 74.8% 76.8% 84.3% 77.0%
2 Years PostTx (%) 46.0% 57.4% 62.6% 70.4% 55.4%
3 Years PostTx (%) 38.5% 49.0% 53.5% 66.7% -
Tac+Siro At Discharge (N) 24 1 - 4 3
At Discharge (%) 100.0% 100.0% - 100.0% 100.0%
1 Year PostTx (%) 29.2% 100.0% - 75.0% -
2 Years PostTx (%) 20.0% 100.0% - 75.0% -
3 Years PostTx (%) 10.0% 100.0% - - -


Source: OPTN/SRTR Data as of May 1, 2007.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen (CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.