Table 12.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1997 to 2006

Recipients with Lung Transplants

  Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Functioning Graft at Discharge 797 753 799 859 951 945 1,010 1,107 1,287 1,307
With Immunosuppression Info 791 751 787 854 948 940 1,006 1,097 1,269 1,294
Corticosteroids Any in Category 98.7% 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.2% 98.0% 97.4%
Steroids 98.7% 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.2% 98.0% 97.4%
Cyclosporine Any in Category 74.5% 73.4% 66.6% 61.9% 52.1% 42.6% 34.7% 29.7% 22.2% 16.1%
Cyclosporin 0.0% 0.0% 0.0% 0.0% 0.4% 0.2% 0.2% 0.2% 0.5% 1.1%
Sandimmmune 16.4% 11.9% 10.8% 6.9% 5.7% 4.5% 4.8% 2.1% 1.7% 1.6%
Neoral 58.0% 61.5% 55.7% 54.0% 39.3% 31.1% 23.1% 20.4% 15.1% 9.2%
Gengraf 0.0% 0.0% 0.0% 1.1% 6.2% 6.7% 6.6% 6.7% 4.8% 4.2%
Eon 0.0% 0.0% 0.1% 0.0% 0.4% 0.1% 0.1% 0.3% 0.2% 0.0%
Tacrolimus Any in Category 24.9% 26.6% 30.0% 38.3% 49.4% 57.1% 65.3% 69.9% 76.2% 82.8%
Tacrolimus 24.9% 26.6% 30.0% 38.3% 49.4% 57.1% 65.3% 69.9% 76.2% 82.8%
Antimetabolites Any in Category 91.0% 92.1% 91.7% 93.7% 91.8% 91.1% 90.0% 90.6% 92.0% 92.8%
Mycophenolate Mofetil 19.0% 22.1% 27.6% 35.6% 41.2% 45.2% 43.7% 46.7% 51.6% 51.9%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.1% 2.5%
Azathioprine 71.9% 69.9% 63.9% 57.8% 50.3% 45.6% 46.2% 43.9% 38.2% 38.5%
Leflunomide 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.1% 0.0%
Cytoxan 0.1% 0.1% 0.3% 0.1% 0.1% 0.2% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.1% 0.1% 0.6% 2.6% 4.1% 1.9% 1.1% 1.3% 0.6% 1.7%
Sirolimus 0.1% 0.1% 0.6% 2.6% 4.1% 1.9% 1.1% 1.3% 0.6% 1.7%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.