Table 11.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1996 to 2005

Recipients with Heart Transplants

  Year of Transplant
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Transplants 2,343 2,293 2,348 2,188 2,199 2,202 2,155 2,057 2,015 2,125
Tx with Follow-up Immunosuppression Info 1,931 1,874 1,932 1,768 1,811 1,849 1,813 1,730 1,742 1,789
Corticosteroids Any in Category 88.7% 87.6% 89.9% 92.5% 92.2% 90.8% 88.4% 85.4% 89.8% 90.0%
Steroids 88.7% 87.6% 89.9% 92.5% 92.2% 90.8% 88.4% 85.4% 89.8% 90.0%
Cyclosporine Any in Category 84.7% 82.7% 78.5% 81.0% 76.8% 63.8% 56.8% 53.5% 49.1% 41.1%
Cyclosporin 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.1% 0.6%
Sandimmmune 19.4% 12.2% 10.4% 7.9% 5.5% 3.4% 2.0% 1.2% 1.3% 1.6%
Neoral 65.3% 70.5% 68.1% 73.0% 67.1% 50.2% 41.9% 38.3% 32.7% 27.4%
Gengraf 0.0% 0.0% 0.0% 0.0% 4.1% 9.7% 12.4% 13.5% 14.7% 11.2%
Eon 0.0% 0.0% 0.0% 0.1% 0.1% 0.3% 0.3% 0.6% 0.3% 0.4%
Tacrolimus Any in Category 15.1% 17.7% 24.4% 27.1% 30.6% 43.4% 50.1% 53.1% 57.0% 64.4%
Tacrolimus 15.1% 17.7% 24.4% 27.1% 30.6% 43.4% 50.1% 53.1% 57.0% 64.4%
Antimetabolites Any in Category 90.8% 90.4% 90.9% 86.4% 90.9% 89.1% 87.3% 88.0% 94.4% 94.7%
Mycophenolate Mofetil 28.2% 47.2% 56.2% 57.5% 72.0% 74.8% 74.1% 78.1% 84.0% 82.4%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 0.3% 0.2% 2.7%
Azathioprine 61.8% 42.7% 34.2% 28.6% 18.7% 14.3% 12.3% 9.5% 10.2% 9.5%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.1%
Cytoxan 0.8% 0.5% 0.6% 0.3% 0.2% 0.0% 0.1% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.2% 0.4% 3.2% 5.0% 7.5% 14.3% 16.4% 12.7% 11.0%
Sirolimus 0.0% 0.2% 0.4% 2.1% 4.7% 7.5% 14.3% 16.4% 12.6% 10.6%
Everolimus 0.0% 0.0% 0.1% 1.0% 0.3% 0.0% 0.0% 0.0% 0.1% 0.4%


Source: OPTN/SRTR Data as of May 1, 2007.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.