Table 11.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1997 to 2006

Recipients with Heart Transplants

  Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Functioning Graft at Discharge 2,068 2,119 1,922 1,982 2,008 1,972 1,897 1,867 1,957 2,040
With Immunosuppression Info 2,048 2,109 1,912 1,976 1,983 1,961 1,883 1,846 1,935 1,982
Corticosteroids Any in Category 95.7% 96.1% 95.5% 94.4% 97.2% 96.9% 92.6% 92.0% 93.3% 92.2%
Steroids 95.7% 96.1% 95.5% 94.4% 97.2% 96.9% 92.6% 92.0% 93.3% 92.2%
Cyclosporine Any in Category 87.8% 85.8% 82.7% 80.4% 70.3% 60.1% 58.5% 50.9% 40.2% 37.9%
Cyclosporin 0.0% 0.0% 0.1% 0.1% 0.1% 0.1% 0.1% 0.2% 0.6% 1.4%
Sandimmmune 18.2% 16.6% 11.2% 8.1% 4.3% 2.8% 3.4% 2.9% 2.1% 1.5%
Neoral 69.5% 69.2% 71.4% 70.6% 57.7% 44.4% 40.6% 33.3% 25.6% 26.6%
Gengraf 0.0% 0.0% 0.0% 1.6% 8.1% 12.6% 14.3% 14.2% 11.2% 8.3%
Eon 0.0% 0.0% 0.0% 0.0% 0.2% 0.2% 0.1% 0.4% 0.7% 0.2%
Tacrolimus Any in Category 9.9% 11.7% 14.1% 16.0% 30.2% 39.6% 41.7% 47.0% 57.8% 59.6%
Tacrolimus 9.9% 11.7% 14.1% 16.0% 30.2% 39.6% 41.7% 47.0% 57.8% 59.6%
Antimetabolites Any in Category 91.9% 92.4% 82.6% 88.2% 91.0% 84.4% 89.2% 94.9% 94.3% 91.4%
Mycophenolate Mofetil 27.4% 41.9% 50.8% 68.3% 75.8% 71.6% 79.6% 85.2% 84.7% 83.3%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.2% 0.1% 1.4% 3.4%
Azathioprine 63.7% 50.0% 31.5% 19.5% 14.9% 12.2% 9.3% 9.6% 8.1% 4.7%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.8% 0.4% 0.3% 0.4% 0.3% 0.2% 0.1% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.2% 1.4% 2.9% 4.3% 10.0% 8.4% 5.4% 4.1% 6.2%
Sirolimus 0.0% 0.1% 0.9% 2.6% 4.3% 10.0% 8.4% 5.2% 3.8% 3.6%
Everolimus 0.0% 0.1% 0.5% 0.4% 0.0% 0.1% 0.0% 0.2% 0.4% 2.5%


Source: OPTN/SRTR Data as of May 1, 2007.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.