Table 10.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1996 to 2005

Recipients with Intestine Transplants

  Year of Transplant
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Transplants 45 68 70 73 82 112 107 116 152 176
Tx with Follow-up Immunosuppression Info 27 31 34 37 55 69 73 88 113 129
Corticosteroids Any in Category 100.0% 93.5% 97.1% 100.0% 100.0% 85.5% 90.4% 83.0% 78.8% 79.1%
Steroids 100.0% 93.5% 97.1% 100.0% 100.0% 85.5% 90.4% 83.0% 78.8% 79.1%
Cyclosporine Any in Category 11.1% 6.5% 2.9% 2.7% 0.0% 0.0% 1.4% 0.0% 0.9% 1.6%
Sandimmmune 0.0% 0.0% 0.0% 2.7% 0.0% 0.0% 1.4% 0.0% 0.0% 0.0%
Neoral 11.1% 6.5% 2.9% 0.0% 0.0% 0.0% 0.0% 0.0% 0.9% 0.8%
Gengraf 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8%
Tacrolimus Any in Category 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 98.9% 97.3% 98.4%
Tacrolimus 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 98.9% 97.3% 98.4%
Antimetabolites Any in Category 66.7% 29.0% 41.2% 37.8% 14.5% 15.9% 11.0% 10.2% 12.4% 19.4%
Mycophenolate Mofetil 44.4% 12.9% 35.3% 21.6% 14.5% 2.9% 9.6% 10.2% 8.0% 13.2%
Azathioprine 22.2% 16.1% 5.9% 16.2% 0.0% 13.0% 1.4% 0.0% 4.4% 6.2%
mTOR Inhibitors Any in Category 0.0% 0.0% 0.0% 21.6% 69.1% 24.6% 28.8% 15.9% 22.1% 24.0%
Sirolimus 0.0% 0.0% 0.0% 21.6% 69.1% 24.6% 28.8% 15.9% 22.1% 24.0%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.