Table 10.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1996 to 2005

Recipients with Intestine Transplants

  Transplant Year
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Transplants 45 68 70 73 82 112 107 116 152 176
Functioning Graft at 1 Year PostTx 27 31 34 37 55 69 73 88 113 129
With Maintenance Use Recorded at 1 Year PostTx 2 7 21 36 55 69 70 87 112 129
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8%
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 1.4% 1.4% 1.1% 0.9% 0.8%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 1.8% 0.0% 0.0% 1.1% 3.6% 0.0%
--- + Steroids 0.0% 0.0% 0.0% 0.0% 1.8% 0.0% 1.4% 3.4% 1.8% 0.8%
CyA + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.9% 1.6%
Tac 0.0% 57.1% 14.3% 2.8% 3.6% 26.1% 21.4% 39.1% 29.5% 37.2%
Tac + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 1.1% 0.0% 1.6%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8%
Tac + MMF/MPA + Steroids 0.0% 14.3% 23.8% 11.1% 9.1% 2.9% 4.3% 6.9% 6.3% 3.9%
Tac + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.7% 1.6%
Tac + OtherAntimet + Steroids 50.0% 0.0% 4.8% 11.1% 0.0% 2.9% 0.0% 0.0% 1.8% 1.6%
Tac + Siro/Evero 0.0% 0.0% 0.0% 2.8% 0.0% 1.4% 1.4% 1.1% 4.5% 2.3%
Tac + Siro/Evero + Steroids 0.0% 0.0% 0.0% 8.3% 21.8% 7.2% 21.4% 4.6% 8.0% 11.6%
Tac + Steroids 50.0% 28.6% 57.1% 61.1% 61.8% 58.0% 47.1% 41.4% 40.2% 35.7%
Other Regimen 0.0% 0.0% 0.0% 2.8% 0.0% 0.0% 1.4% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.