Table 12.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1994 to 2003

Recipients with Lung Transplants

  Year of Transplant
1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Transplants 740 893 836 948 893 922 977 1,083 1,054 1,099
Tx with Follow-up Immunosuppression Info 526 634 564 673 626 664 735 802 827 859
Corticosteroids Any in Category 98.1% 99.1% 99.3% 98.2% 99.5% 99.1% 98.6% 99.5% 97.0% 97.9%
Steroids 98.1% 99.1% 99.3% 98.2% 99.5% 99.1% 98.6% 99.5% 97.0% 97.9%
Cyclosporine Any in Category 81.2% 70.7% 69.9% 62.0% 63.9% 63.7% 54.6% 46.0% 35.3% 30.7%
Cyclosporin 71.5% 1.1% 0.0% 0.0% 0.0% 0.0% 0.3% 0.5% 0.1% 0.0%
Sandimmmune 7.8% 35.5% 14.0% 8.0% 6.5% 4.7% 4.2% 5.0% 2.5% 2.7%
Neoral 1.9% 34.1% 55.7% 53.8% 57.3% 58.6% 48.2% 34.0% 26.0% 21.0%
Gengraf 0.0% 0.0% 0.0% 0.1% 0.0% 0.3% 1.9% 6.4% 6.5% 6.9%
Eon 0.0% 0.0% 0.2% 0.0% 0.0% 0.2% 0.0% 0.1% 0.1% 0.2%
Tacrolimus Any in Category 12.0% 23.2% 33.7% 37.7% 41.9% 46.5% 55.6% 69.2% 75.7% 76.7%
Tacrolimus 12.0% 23.2% 33.7% 37.7% 41.9% 46.5% 55.6% 69.2% 75.7% 76.7%
Antimetabolites Any in Category 96.0% 90.5% 88.7% 88.4% 92.8% 91.4% 94.3% 90.8% 88.8% 87.8%
Mycophenolate Mofetil 1.3% 10.6% 19.9% 30.3% 30.4% 33.9% 40.8% 42.3% 45.1% 46.2%
Azathioprine 94.5% 79.3% 68.4% 57.5% 62.3% 57.5% 53.3% 48.1% 43.7% 41.6%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.0% 0.0%
Cytoxan 0.2% 0.6% 0.4% 0.6% 0.2% 0.0% 0.1% 0.1% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.0% 0.0% 0.0% 0.3% 6.2% 6.3% 11.0% 14.4% 10.2%
Sirolimus 0.0% 0.0% 0.0% 0.0% 0.2% 5.9% 6.3% 11.0% 14.4% 10.2%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.2% 0.3% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 2, 2005.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug withinthe same category.