Table 12.6d

Immunosuppression Use: Antirejection Treatment from Transplant

to One Year Posttransplant, 1993 to 2002

Recipients with Lung Transplants

  Year of Transplant
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002
Transplants 674 738 893 836 946 893 920 977 1,083 1,054
Tx with Antirejection Treatments 379 388 475 381 419 402 394 432 500 427
Antibodies Category Usage 14.2% 17.8% 9.5% 10.8% 11.7% 15.9% 16.2% 18.8% 11.4% 13.6%
ALG 0.3% 1.3% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
ATG/NRATG/NRATS 5.3% 10.6% 5.7% 7.3% 7.9% 10.9% 8.1% 7.4% 4.2% 3.3%
OKT3 9.5% 7.7% 4.2% 3.7% 4.3% 3.2% 3.0% 2.5% 1.4% 2.1%
Thymoglobulin 0.0% 0.0% 0.2% 0.0% 0.0% 0.7% 5.1% 5.8% 6.0% 4.9%
Zenapax 0.0% 0.0% 0.0% 0.0% 0.2% 2.2% 1.0% 3.0% 0.8% 5.2%
Simulect 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.8% 2.8% 0.6% 0.2%
Campath 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.5%
Corticosteroids Category Usage 91.0% 92.5% 93.7% 90.0% 94.0% 91.5% 92.9% 88.2% 92.4% 94.8%
Steroids 91.0% 92.5% 93.7% 90.0% 94.0% 91.5% 92.9% 88.2% 92.4% 94.8%
Antimetabolites Category Usage 4.5% 3.1% 1.1% 5.0% 1.9% 0.7% 1.5% 1.2% 1.2% 0.2%
Cytoxan 0.0% 0.8% 0.0% 0.8% 0.5% 0.2% 0.8% 0.5% 0.2% 0.2%
Methotrexate 4.5% 2.3% 1.1% 4.2% 1.4% 0.5% 1.5% 0.7% 1.0% 0.0%

Source: OPTN/SRTR Data as of May 3, 2004.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may

be prescribed more than one drug within the same category.